Nature + Computing

Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure

Santiago Avila-Rios, Jonathan M. Carlson, Mina John, Simon Mallal, Zabrina L Brumme

Current Opinion in HIV and AIDS | May 2019, Vol 14(3): pp. 194-204

Publication Projet

Genotypic and mechanistic characterization of subtype-specific hiv adaptation to host cellular immunity

Natalie N Kinloch, Guinevere Q Lee, Jonathan M. Carlson, Steven W Jin, Chanson J Brumme, Helen Byakwaga, Conrad Muzoora, Mwebesa B Bwana, Kyle D Cobarrubias, Peter W Hunt, Jeff N Martin, Mary Carrington, David R Bangsberg, P Richard Harrigan, Mark A Brockman, Zabrina L Brumme

Journal of Virology | January 2019, Vol 93(1): pp. e01502-18

Publication Projet

Antisense-derived HIV-1 cryptic epitopes are not major drivers of viral evolution during the acute phase of infection

Binghao J Peng, Jonathan M. Carlson, Michael KP Liu, Feng Gao, Nilu Goonetilleke, Andrew J McMichael, Persephone Borrow, Jill Gilmour, Sonya L Heath, Eric Hunter, Anju Bansal, Paul A Goepfert

Journal of Virology | October 2018, Vol 92(19): pp. e00711-18

Publication Projet

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

Maureen P. Martin, Vivek Naranbhai, Patrick R. Shea, Ying Qi, Veron Ramsuran, Nicolas Vince, Xiaojiang Gao, Rasmi Thomas, Zabrina L. Brumme, Jonathan M. Carlson, Steven M. Wolinsky, James J. Goedert, Bruce D. Walker, Florencia P. Segal, Steven G. Deeks, David W. Haas, Stephen A. Migueles, Mark Connors, Nelson Michael, Jacques Fellay, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Bernard A. Lafont, Phillip Pymm, Philippa M. Saunders, Jacqueline Widjaja, Shu Cheng Wong, Julian P. Vivian, Jamie Rossjohn, Andrew G. Brooks,, Mary Carrington

Journal of Clinical Investigation | May 2018, Vol 128(5): pp. 1903-1912

Publication Publication Projet

HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation

Thushan I. de Silva, Aleksandra Leligdowicz, Jonathan M. Carlson, Miguel Garcia-Knight, Clayton Onyango, Nicholas Miller, Louis-Marie Yindom, Stephane Hué, Assan Jaye, Tao Dong, Matthew Cotten, Sarah L Rowland-Jones

AIDS | March 2018, Vol 32(6): pp. 709-714

Publication Projet

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.

Veron Ramsuran, Vivek Naranbhai, Amir Horowitz, Ying Qi, Maureen P. Martin, Yuko Yuki, Xiaojiang Gao, Victoria Walker-Sperling, Gregory Q. Del Prete, Douglas K. Schneider, Jeffrey D. Lifson, Jacques Fellay, Steven G. Deeks, Jeffrey N. Martin, James J. Goedert, Steven M. Wolinsky, Nelson L. Michael, Gregory D. Kirk, Susan Buchbinder, David Haas, Thumbi Ndung’u, Philip Goulder, Peter Parham, Bruce D. Walker, Jonathan M. Carlson, Mary Carrington

Science | January 2018, Vol 359: pp. 86-90

Publication Publication

Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure

Santiago Avila-Rios, Jonathan M. Carlson, Mina John, Simon Mallal, Zabrina L Brumme

Current Opinion in HIV and AIDS | May 2019, Vol 14(3): pp. 194-204

Publication Projet

Genotypic and mechanistic characterization of subtype-specific hiv adaptation to host cellular immunity

Natalie N Kinloch, Guinevere Q Lee, Jonathan M. Carlson, Steven W Jin, Chanson J Brumme, Helen Byakwaga, Conrad Muzoora, Mwebesa B Bwana, Kyle D Cobarrubias, Peter W Hunt, Jeff N Martin, Mary Carrington, David R Bangsberg, P Richard Harrigan, Mark A Brockman, Zabrina L Brumme

Journal of Virology | January 2019, Vol 93(1): pp. e01502-18

Publication Projet

Antisense-derived HIV-1 cryptic epitopes are not major drivers of viral evolution during the acute phase of infection

Binghao J Peng, Jonathan M. Carlson, Michael KP Liu, Feng Gao, Nilu Goonetilleke, Andrew J McMichael, Persephone Borrow, Jill Gilmour, Sonya L Heath, Eric Hunter, Anju Bansal, Paul A Goepfert

Journal of Virology | October 2018, Vol 92(19): pp. e00711-18

Publication Projet

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

Maureen P. Martin, Vivek Naranbhai, Patrick R. Shea, Ying Qi, Veron Ramsuran, Nicolas Vince, Xiaojiang Gao, Rasmi Thomas, Zabrina L. Brumme, Jonathan M. Carlson, Steven M. Wolinsky, James J. Goedert, Bruce D. Walker, Florencia P. Segal, Steven G. Deeks, David W. Haas, Stephen A. Migueles, Mark Connors, Nelson Michael, Jacques Fellay, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Bernard A. Lafont, Phillip Pymm, Philippa M. Saunders, Jacqueline Widjaja, Shu Cheng Wong, Julian P. Vivian, Jamie Rossjohn, Andrew G. Brooks,, Mary Carrington

Journal of Clinical Investigation | May 2018, Vol 128(5): pp. 1903-1912

Publication Publication Projet

HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation

Thushan I. de Silva, Aleksandra Leligdowicz, Jonathan M. Carlson, Miguel Garcia-Knight, Clayton Onyango, Nicholas Miller, Louis-Marie Yindom, Stephane Hué, Assan Jaye, Tao Dong, Matthew Cotten, Sarah L Rowland-Jones

AIDS | March 2018, Vol 32(6): pp. 709-714

Publication Projet

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.

Veron Ramsuran, Vivek Naranbhai, Amir Horowitz, Ying Qi, Maureen P. Martin, Yuko Yuki, Xiaojiang Gao, Victoria Walker-Sperling, Gregory Q. Del Prete, Douglas K. Schneider, Jeffrey D. Lifson, Jacques Fellay, Steven G. Deeks, Jeffrey N. Martin, James J. Goedert, Steven M. Wolinsky, Nelson L. Michael, Gregory D. Kirk, Susan Buchbinder, David Haas, Thumbi Ndung’u, Philip Goulder, Peter Parham, Bruce D. Walker, Jonathan M. Carlson, Mary Carrington

Science | January 2018, Vol 359: pp. 86-90

Publication Publication

Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure

Santiago Avila-Rios, Jonathan M. Carlson, Mina John, Simon Mallal, Zabrina L Brumme

Current Opinion in HIV and AIDS | May 2019, Vol 14(3): pp. 194-204

Publication Projet

Genotypic and mechanistic characterization of subtype-specific hiv adaptation to host cellular immunity

Natalie N Kinloch, Guinevere Q Lee, Jonathan M. Carlson, Steven W Jin, Chanson J Brumme, Helen Byakwaga, Conrad Muzoora, Mwebesa B Bwana, Kyle D Cobarrubias, Peter W Hunt, Jeff N Martin, Mary Carrington, David R Bangsberg, P Richard Harrigan, Mark A Brockman, Zabrina L Brumme

Journal of Virology | January 2019, Vol 93(1): pp. e01502-18

Publication Projet

Antisense-derived HIV-1 cryptic epitopes are not major drivers of viral evolution during the acute phase of infection

Binghao J Peng, Jonathan M. Carlson, Michael KP Liu, Feng Gao, Nilu Goonetilleke, Andrew J McMichael, Persephone Borrow, Jill Gilmour, Sonya L Heath, Eric Hunter, Anju Bansal, Paul A Goepfert

Journal of Virology | October 2018, Vol 92(19): pp. e00711-18

Publication Projet

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

Maureen P. Martin, Vivek Naranbhai, Patrick R. Shea, Ying Qi, Veron Ramsuran, Nicolas Vince, Xiaojiang Gao, Rasmi Thomas, Zabrina L. Brumme, Jonathan M. Carlson, Steven M. Wolinsky, James J. Goedert, Bruce D. Walker, Florencia P. Segal, Steven G. Deeks, David W. Haas, Stephen A. Migueles, Mark Connors, Nelson Michael, Jacques Fellay, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Bernard A. Lafont, Phillip Pymm, Philippa M. Saunders, Jacqueline Widjaja, Shu Cheng Wong, Julian P. Vivian, Jamie Rossjohn, Andrew G. Brooks,, Mary Carrington

Journal of Clinical Investigation | May 2018, Vol 128(5): pp. 1903-1912

Publication Publication Projet

HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation

Thushan I. de Silva, Aleksandra Leligdowicz, Jonathan M. Carlson, Miguel Garcia-Knight, Clayton Onyango, Nicholas Miller, Louis-Marie Yindom, Stephane Hué, Assan Jaye, Tao Dong, Matthew Cotten, Sarah L Rowland-Jones

AIDS | March 2018, Vol 32(6): pp. 709-714

Publication Projet

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.

Veron Ramsuran, Vivek Naranbhai, Amir Horowitz, Ying Qi, Maureen P. Martin, Yuko Yuki, Xiaojiang Gao, Victoria Walker-Sperling, Gregory Q. Del Prete, Douglas K. Schneider, Jeffrey D. Lifson, Jacques Fellay, Steven G. Deeks, Jeffrey N. Martin, James J. Goedert, Steven M. Wolinsky, Nelson L. Michael, Gregory D. Kirk, Susan Buchbinder, David Haas, Thumbi Ndung’u, Philip Goulder, Peter Parham, Bruce D. Walker, Jonathan M. Carlson, Mary Carrington

Science | January 2018, Vol 359: pp. 86-90

Publication Publication