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)11.2(par)11.9(s)0.9(i)-9.6(n)11.4(g)22.6(.)-15.2( )]TJ 1.2285 -1.1503 TD 0.0025 Tc 0.1607 Tw [(We bel)12.5(i)1.3(ev)11.1(e tha)11(t)12.5( )-11.2(th)11.1(e ide)11(n)-0.1(t)12.5(i)1.3(f)11.6(i)1.3(cat)12.5(i)-9.9(o)11.1(n)11.1( )-11.2(of)11.6( )-11.2(unk)22.3(now)20.9(n )]TJ -1.2285 -1.1503 TD 0.0023 Tc 0.0604 Tw [(w)9.6(o)10.9(r)-10.9(d)10.9(s sh)10.9(ou)10.9(ld)10.9( )11.2(not)12.3( b)10.9(e)10.8( )11.2(def)11.4(i)-10.1(n)22.1(e)10.8(d)10.9( as)11.6( a)10.8( )11.2(sep)10.9(a)10.8(r)-10.9(a)10.8(te)10.8( )11.2(pr)11.4(obl)12.3(em)9.7( )]TJ 0 -1.1391 TD 0.0025 Tc 0.1272 Tw [(fro)11.1(m w)20.9(o)-0.1(rd)11.1( s)11.8(e)-0.2(g)11.1(m)9.9(en)11.1(t)-9.9(a)-0.2(t)12.5(i)1.3(on)11.1(.)6.8( )22.3(T)-11.9(h)11.1(e)11(s)0.6(e)11( )11.2(t)-9.9(w)20.9(o p)11.1(r)0.5(ob)22.3(l)-9.9(e)-0.2(m)9.9(s)11.8( )11.2(are)11( )]TJ 0 -1.1503 TD 0.0022 Tc 0.0382 Tw [(better)11.3( )11.2(solv)10.8(ed)10.8( s)11.5(i)1(m)9.6(u)-0.4(ltane)10.7(o)10.8(u)-0.4(sl)12.2(y)22( )-11.1(in a)10.7( un)10.8(if)11.3(ied)10.8( )11.2(appr)11.3(oach)10.8(.)17.7( )]TJ 0 -1.1391 TD 0.0025 Tc 0.183 Tw [(O)-12.6(n)11.1(e)11( ex)11.1(am)9.9(ple)11( of)11.6( )11.1(such)22.3( a)11(p)-0.1(p)11.1(r)0.5(oach)22.3(es)11.8( is S)22.4(p)-0.1(roa)11(t)12.5( et)12.5( a)11(l)1.3(.)6.8( )]TJ T* 0.002 Tc 0.3064 Tw [(\()-11.2(1)10.6(996)10.6(\))11.1(,)6.3( )-22.3(w)20.4(h)-0.6(ich)10.6( i)-10.4(s)11.3( ba)10.5(sed)10.6( )-11.2(o)21.8(n)10.6( )-22.3(w)20.4(e)-0.7(ig)10.6(hted)10.6( )-11.2(fin)10.6(i)0.8(t)12(e)-0.7(-)11.1(s)-11(ta)10.5(te)10.5( )]TJ 0 -1.1615 TD 0.0026 Tc 0.1159 Tw [(t)-9.8(r)0.6(an)11.2(sd)11.2(uc)11.1(er)11.7(s)11.9( \(FS)11.4(T)10.5(s\).)6.9( )11.1(Ou)11.2(r)11.7( ap)11.2(proac)11.1(h)22.4( )-11.2(i)12.6(s)11.9( m)10(o)0(t)12.6(i)-9.8(v)22.4(a)-0.1(t)-9.8(e)-0.1(d)22.4( by)22.4( )]TJ 0 -1.1391 TD -0.0086 Tc 0.2276 Tw [(t)-21(h)0(e s)-10.5(a)-11.3(me i)-9.8(n)0(s)-10.5(p)-11.2(ir)-10.6(at)-21(i)-9.8(on, )-11.2(b)-11.2(u)11.2(t)-9.8( )11.1(i)-9.8(s)0.7( b)-11.2(a)-11.3(se)-11.3(d)11.2( )-11.2(on )-11.2(a )11.1(di)-9.8(f)-10.6(f)0.5(e)-11.3(r)-10.6(e)-11.3(n)-11.2(t )]TJ T* 0.0023 Tc 0.1274 Tw [(m)9.7(echani)12.3(s)0.4(m)9.7(:)1.1( )-11.2(th)10.9(e im)9.7(prov)10.9(ed)22.1( sourc)10.8(e)-0.4(-)11.4(c)-0.4(hann)22.1(el )-11.2(m)9.7(o)10.9(de)10.8(l)-10.1(s)11.6(.)6.6( )]TJ 0 -1.1503 TD -0.0083 Tc 0.3167 Tw [(A)-23.4(s)1( we)11.3( )-11.2(s)-10.2(h)0.3(a)-11(ll )-11.2(se)-11(e, t)-9.5(h)-10.9(e)-11(s)1(e mo)-10.9(de)-11(l)-20.7(s)1( )11.2(p)-10.9(r)-10.3(o)-10.9(v)0.3(i)-9.5(d)-10.9(e )11.2(a )-11.2(mor)-10.3(e)0.2( )]TJ 0 -1.1391 TD 0.0022 Tc 0.0717 Tw [(flex)10.8(ible)10.7( f)11.3(r)0.2(am)9.6(ew)9.5(o)10.8(r)-11(k)22( )-11.1(to)10.8( )11.2(inco)10.8(rpo)10.8(r)0.2(ate)10.7( v)10.8(a)-0.5(r)11.3(i)1(ous)11.5( k)10.8(i)1(nd)10.8(s)11.5( of)22.5( )]TJ 0 -1.1503 TD 0.1722 Tw [(l)-10.2(e)-0.5(x)22(i)-10.2(ca)10.7(l)12.2( )-11.1(an)10.8(d)10.8( s)11.5(t)-10.2(a)10.7(tis)11.5(t)-10.2(i)12.2(cal)12.2( inf)11.3(o)-0.4(r)11.3(m)9.6(at)-10.2(ion)22(.)-4.7( S)11(o)-0.4(m)9.6(e)10.7( t)-10.2(y)33.2(pes )-11.1(of)22.5( )]TJ T* -0.0087 Tc 0.1272 Tw [(u)-11.3(n)-11.3(kno)-11.3(wn wor)-21.9(d)-0.1(s)-10.6( t)-9.9(h)-11.3(at a)-11.4(r)0.4(e no)-11.3(t d)-11.3(i)1.3(s)-10.6(c)-11.4(us)-10.6(s)-10.6(e)-11.4(d )11.1(i)-9.9(n)-0.1( Sp)-11.3(r)-10.7(o)-0.1(at)-9.9()-10.7(s)0.6( )]TJ 0 -1.1391 TD 0.0018 Tc 0.0051 Tw [(s)-11.2(y)32.8(st)-10.6(e)10.3(m)-1.9( are)10.3( )11.2(dea)10.3(lt w)20.2(i)-10.6(th)10.4( )11.2(in)10.4( )-11.1(o)21.6(u)-0.8(r)10.9( )-11.1(sy)32.8(stem)9.2(.)]TJ 10.2782 0 0 10.2782 224.041 308.0788 Tm 0 Tc 0 Tw ( )Tj /F3 1 Tf 11.6798 0 0 11.6798 70.201 282.9988 Tm (3)Tj /F2 1 Tf 0.5034 0 TD ( )Tj /F3 1 Tf 1.8596 0 TD -0.0008 Tc -0.0026 Tw [(Chinese W)-7.7(o)6(r)-8.9(d)0.4(s )]TJ /F5 1 Tf 10.7452 0 0 10.7452 70.201 264.8788 Tm 0.002 Tc 0.0384 Tw [(T)-12.4(h)-0.6(e)10.5(r)0(e)10.5( is)11.3( )-11.1(n)10.6(o)10.6( )-11.1(s)11.3(t)-10.4(an)10.6(d)10.6(a)-0.7(rd)10.6( def)11.1(i)-10.4(n)21.8(ition)10.6( of)11.1( C)-12.2(h)10.6(ine)10.5(s)0.1(e)10.5( )-11.1(w)20.4(o)-0.6(rds)11.3( )-11.1()10.6( )]TJ 0 -1.1503 TD 0.0029 Tc 0.004 Tw [(l)-9.5(i)1.7(ng)11.5(u)11.5(i)-9.5(s)12.2(t)1.7(s)12.2( m)10.3(a)0.2(y)33.9( )-11.1(d)11.5(e)0.2(fine)11.4( w)21.3(o)0.3(rds)12.2( )11.2(fro)11.5(m m)10.3(a)0.2(n)-10.8(y)33.9( as)12.2(pec)11.4(t)1.7(s)12.2( )11.2(\(e)11.4(.)-15.1(g)11.5(.)18.4( )]TJ 0 -1.1391 TD 0.0023 Tc 0.1274 Tw [(Pack)10.9(ard)22.1(,)-15.7( )11.2(20)10.9(00)10.9(\))11.4(,)-15.7( )11.2(bu)10.9(t n)10.9(o)-0.3(n)10.9(e)-0.4( )11.2(of)11.4( the)10.8(s)0.4(e)10.8( def)11.4(i)1.1(n)10.9(itions)11.6( w)20.7(i)1.1(l)-10.1(l)23.4( )]TJ 0 -1.1503 TD 0.0019 Tc 0.0161 Tw [(com)9.3(p)-0.7(le)10.4(tel)-10.5(y)32.9( line)10.4( )-11.2(u)10.5(p)10.5( w)9.2(ith)10.5( an)10.5(y)21.7( other)11(.)-5( Fo)10.5(rtun)10.5(a)10.4(t)-10.5(e)10.4(l)-10.5(y)32.9(,)-5( this)22.4( )]TJ T* 0.0021 Tc 0.1611 Tw [(m)9.5(a)-11.8(y)33.1( not m)9.5(a)-0.6(tter)11.2( )11.2(in )11.2(pra)10.6(c)-0.6(t)12.1(i)0.9(ce)10.6( be)10.6(cau)10.7(s)11.4(e)-0.6( )11.2(t)-10.3(h)10.7(e)10.6( d)10.7(e)-0.6(f)11.2(i)-10.3(n)10.7(itio)10.7(n)10.7( )]TJ 0 -1.1391 TD 0.0022 Tc 0.1722 Tw [(t)-10.2(h)10.8(at )11.2(is)11.5( m)9.6(o)-0.4(s)11.5(t)12.2( us)11.5(ef)11.3(ul)12.2( w)9.5(ill)12.2( d)10.8(e)10.7(pend)22( t)-10.2(o)22( )11.2(a)10.7( larg)10.8(e)10.7( )11.2(deg)10.8(r)0.2(ee)10.7( )]TJ T* 0.0027 Tc 0.0042 Tw [(upon)22.5( )-11.1(ho)11.3(w)10( on)11.3(e)11.2( use)11.2(s)12( an)11.3(d)11.3( pro)11.3(cess)12(e)0(s)12( )11.2(thes)12(e)11.2( w)10(o)11.3(r)-10.5(d)11.3(s)12(.)-15.3( )]TJ 1.2396 -1.1503 TD 0.0029 Tc 0.004 Tw [(We)11.4( def)12(i)-9.5(n)22.7(e)11.4( )-11.1(C)11(h)0.3(in)11.5(ese)11.4( w)21.3(o)0.3(rds)12.2( in )11.2(thi)12.9(s)12.2( )-11.1(pa)11.4(pe)11.4(r)12( )-11.1(as)12.2( )11.2(one)11.4( of)23.2( )]TJ -1.2396 -1.1503 TD 0.0124 Tc 0.1731 Tw [(th)21(e)20.9( )-11.2(f)21.5(o)21(ll)11.2(o)9.8(w)30.8(i)11.2(n)9.8(g)21( )-11.2(f)21.5(o)9.8(u)32.2(r)10.4( )-11.2(t)11.2(y)43.4(p)9.8(e)20.9(s)10.5(:)0( \()10.4(1)9.8(\))21.5( e)9.7(n)32.2(tr)10.4(i)22.4(e)9.7(s)21.7( in)32.2( a)20.9( l)11.2(e)9.7(x)21(i)11.2(c)9.7(o)9.8(n)32.2( )]TJ 0 -1.1391 TD 0 Tc 0 Tw (\()Tj /F6 1 Tf 0.3462 0 TD 0.0018 Tc -0.0061 Tw [(le)10.3(xic)10.3(o)-0.8(n)21.6( w)9.9(o)-0.8(rds)]TJ /F5 1 Tf 5.5392 0 TD 0.0023 Tc -0.0289 Tw [( bel)12.3(o)-0.3(w)20.7(\))-10.9(,)6.6( )-11.1(\()-10.9(2)22.1(\) m)9.7(o)-0.3(rpho)10.9(l)-10.1(o)10.9(g)10.9(i)-10.1(c)10.8(a)10.8(l)1.1(l)-10.1(y)33.3( )-11.1(deriv)10.9(e)-0.4(d)10.9( )]TJ -5.8854 -1.1391 TD -0.0084 Tc 0.0153 Tw [(wor)-21.6(d)0.2(s)-10.3(,)-15.3( \(3)-11(\) )-11.1(fa)-11.1(ct)-9.6(o)-11(i)-9.6(ds, )-11.1(a)-11.1(nd \()-10.4(4)-11(\) )11.2(n)-11(a)-11.1(me)-11.1(d e)-11.1(n)-11(tit)-20.8(i)-9.6(e)0.1(s, )-11.1(be)-11.1(ca)-11.1(u)-11(s)0.9(e )]TJ 0 -1.1503 TD -0.0089 Tc 0.1274 Tw [(t)-21.3(h)-0.3(e)-11.6(s)0.4(e f)-10.9(o)-0.3(u)-11.5(r)0.2( )11.1(t)-32.4(y)22.1(pe)-11.6(s)-10.8( o)-11.5(f)0.2( )-11.2(w)9.5(o)-11.5(r)-10.9(d)-0.3(s)-10.8( )11.1(ha)-11.6(ve)-11.6( di)-10.1(ff)-10.9(e)-11.6(r)-10.9(e)-11.6(n)-0.3(t)-10.1( fu)-11.5(nc)-11.6(ti)-10.1(o)-11.5(n)-11.5(-)]TJ 0 -1.1391 TD 0.0023 Tc 0.3173 Tw [(al)-10.1(i)12.3(tie)10.8(s in)10.9( Chi)12.3(n)-0.3(es)11.6(e lang)22.1(ua)10.8(g)10.9(e)-0.4( proce)10.8(s)0.4(s)11.6(i)1.1(ng)10.9(,)6.6( )-11.1(and)22.1( )-11.1(a)10.8(r)0.3(e)10.8( )]TJ 21.8554 56.6879 TD 0.0024 Tc 0.306 Tw [(proc)10.9(e)10.9(sse)10.9(d)11( )-11.2(i)12.4(n)11( di)-10(f)11.5(f)11.5(e)-0.3(r)11.5(e)-0.3(nt)12.4( )-11.2(w)20.8(a)10.9(y)22.2(s)0.5( i)-10(n)11( ou)11(r)11.5( )-11.2(s)-10.6(y)44.5(st)-10(em)9.8(.)6.7( F)11.2(o)-0.2(r)11.5( )]TJ 0 -1.1503 TD -0.0087 Tc 0.1607 Tw [(e)-11.4(x)11.1(a)-11.4(m)-12.4(pl)-21.1(e,)-15.6( )11.1(t)-9.9(h)-11.2(e pl)-9.9(a)-11.4(u)-11.3(si)-9.9(bl)-9.9(e w)9.7(o)-11.3(r)-10.7(d)-11.2( )11.1(s)-10.6(e)-11.4(gme)-11.4(n)-11.3(t)-9.9(a)-0.2(t)-9.9(i)-21.1(o)11.1(n)-11.2( fo)-11.3(r )11.1(t)-21.1(h)-0.1(e )]TJ T* 0.0826 Tw [(s)-10.6(e)-11.4(n)-11.3(t)1.3(e)-11.4(n)-11.3(ce i)-9.9(n)-0.1( Fi)-21.1(gur)-21.9(e)10.9( )-11.1(1)11.1(\()-21.9(a)-11.4(\))0.4( )11.2(i)-9.9(s)0.6( )-11.1(as)-10.6( sh)-11.3(own.)-15.6( F)-11.1(i)-9.9(gur)-21.9(e 1\()-10.7(b)-11.3(\))0.4( is )]TJ 0 -1.1391 TD 0.0027 Tc 0.06 Tw [(the)11.2( out)12.7(pu)11.3(t of)23( )-11.2(ou)11.3(r)11.8( s)-10.3(y)33.7(stem)10.1(, w)21.1(h)0.1(ere)11.2( )-11.2(w)10(o)11.3(r)-10.5(d)11.3(s)12( )-22.3(o)11.3(f)11.8( )-11.2(d)11.3(i)1.5(f)11.8(f)11.8(e)0(ren)11.3(t)12.7( )]TJ T* 0.0022 Tc 0.0047 Tw [(t)-10.2(y)33.2(pes ar)11.3(e)10.7( pr)11.3(oces)11.5(sed)10.8( )11.2(in)10.8( )-11.1(d)22(i)-10.2(f)11.3(f)11.3(e)-0.5(rent)12.2( )-11.1(w)20.6(a)-11.7(y)33.1(s)0.3(: )]TJ 8.76 0 0 8.76 310.3209 661.9588 Tm -0.0049 Tc 0 Tw (\(a\))Tj ET q 1 i 319.921 659.799 7.08 9.96 re W n BT 8.76 0 0 8.76 319.9209 661.9588 Tm 0 Tc ( )Tj ET Q BT /TT1 1 Tf 8.76 0 0 8.76 332.2809 661.1188 Tm 0 Tc (!"#)Tj /F5 1 Tf 3 0 TD (/)Tj /TT1 1 Tf 0.274 0 TD ($%&'$\()Tj /F5 1 Tf 6 0 TD (/)Tj /TT1 1 Tf 0.274 0 TD (\)\)**)Tj /F5 1 Tf 4 0 TD (/)Tj /TT1 1 Tf 0.2877 0 TD (+)Tj /F5 1 Tf 1 0 TD (/)Tj /TT1 1 Tf 0.274 0 TD (,-.)Tj /F5 1 Tf 3 0 TD (/)Tj /TT1 1 Tf 0.2877 0 TD (/0)Tj /F5 1 Tf 2 0 TD (/)Tj /TT1 1 Tf 0.274 0 TD (1)Tj /F5 1 Tf 1 0 TD (/)Tj /TT1 1 Tf -21.6712 -1.3014 TD (23)Tj /F5 1 Tf 2 0 TD 0.0074 Tc -0.0108 Tw [( )13.7(\()11.6(F)1.8(rie)26.7(n)0.5(ds)12.8( ha)13(ppi)11.4(l)-2.3(y)14.2( g)27.9(o)0.5( t)11.4(o)0.5( pr)11.6(o)14.2(f)-2.1(es)12.8(s)12.8(o)14.2(r Li)11.4( Juns)12.8(he)26.7(ng)27.9(s )]TJ -2 -1.1918 TD 0.0082 Tc -0.0116 Tw [(ho)15.1(m)19.1(e)13.8( fo)15(r l)12.2(unc)13.8(h a)13.8(t)12.2( t)12.2(w)-9.5(e)27.5(l)-1.5(ve )13.7(t)12.2(h)1.3(ir)12.4(ty)15(.)25.3(\))-15( )]TJ ET 1 i 305.041 674.439 21.6 -1.44 re f 326.641 674.439 1.32 -1.44 re f 327.961 674.439 204.48 -1.44 re f BT 8.76 0 0 8.76 310.3209 626.3188 Tm -0.0042 Tc 0 Tw [(\(b)-11(\))]TJ ET q 320.521 624.159 6.48 9.96 re W n BT 8.76 0 0 8.76 320.5209 626.3188 Tm 0 Tc ( )Tj ET Q BT 8.76 0 0 8.76 332.2809 625.4788 Tm 0 Tc ([)Tj /TT1 1 Tf 0.3425 0 TD (!")Tj /F5 1 Tf 2 0 TD (+)Tj /TT1 1 Tf 0.5616 0 TD (#)Tj /F5 1 Tf 1 0 TD 0.0027 Tc -0.0198 Tw [( MA_)-4.2(S)10.8(])-6.8( [)]TJ /TT1 1 Tf 3.8356 0 TD 0 Tc 0 Tw [($%&'$)13.7(\()]TJ /F5 1 Tf 5.9863 0 TD 0.0076 Tc -0.011 Tw [( 12:)11.6(30 T)15.9(I)11.8(M)6.2(E)2.2(] )27.4([)]TJ /TT1 1 Tf 6.1507 0 TD 0 Tc 0 Tw (\)*)Tj /F5 1 Tf -19.8767 -1.3151 TD 0.0038 Tc -0.0209 Tw [(MR)13.3(_AAB)13.3(B])-5.7( [)]TJ /TT1 1 Tf 5.7534 0 TD 0 Tc 0 Tw (+)Tj /F5 1 Tf 0.9863 0 TD 0.0095 Tc -0.0266 Tw (] [)Tj /TT1 1 Tf 0.9315 0 TD 0 Tc 0 Tw (,-.)Tj /F5 1 Tf 3 0 TD 0.0076 Tc -0.011 Tw [( PN)17.3(] )13.7([)]TJ /TT1 1 Tf 2.4247 0 TD 0 Tc 0 Tw (/0)Tj /F5 1 Tf 2 0 TD 0.0232 Tc -0.054 Tw (] [)Tj /TT1 1 Tf 0.9315 0 TD 0 Tc 0 Tw (1)Tj /F5 1 Tf 0.9863 0 TD 0.0232 Tc -0.054 Tw (] [)Tj /TT1 1 Tf 0.9315 0 TD 0 Tc 0 Tw (23)Tj /F5 1 Tf 1.9863 0 TD 0.0095 Tc (] )Tj /F3 1 Tf -22.4384 -1.6849 TD -0.0056 Tc -0.0115 Tw [(F)16.4(i)-15.3(g)-12.4(u)-11.2(re 1)-12.5(:)]TJ /F5 1 Tf 3.9041 0 TD -0.0059 Tc 0.0025 Tw [( )13.7(\()-29.1(a)-0.3(\) )-13.7(A Ch)-12.8(i)-15.6(n)-26.4(e)13.4(s)-14.2(e s)-14.2(e)13.4(n)-12.7(t)-15.6(enc)-27.7(e)-0.3(. S)-11.5(l)-1.9(ash)-12.8(e)-14(s )13.7(i)-15.6(n)-12.8(d)-12.7(i)-1.9(cat)-29.3(e)13.4( w)-9.9(o)1(rd)-12.8( )]TJ -3.9041 -1.1507 TD -0.005 Tc 0.0016 Tw [(b)-11.9(o)1.8(u)-11.8(n)-11.9(d)-11.8(a)0.6(ries. \(b)-11.9(\) A)-9(n)-11.8( ou)-11.9(tp)-11.9(u)-11.8(t)-14.7( )13.7(of)-14.5( )13.7(ou)-11.9(r)-28.2( w)-9(o)1.9(rd)-11.9( s)-13.3(e)0.6(gm)-7.8(e)14.3(n)-11.9(t)-14.7(a)0.6(ti)-14.7(on)-25.5( )13.7(s)-13.3(y)1.9(st)-14.7(em)-7.8(. )]TJ 0 -1.1644 TD 0.0077 Tc -0.0111 Tw [(S)15.8(quar)11.9(e)27( br)11.9(a)13.3(c)-0.4(ke)27(ts )13.7(indi)11.7(c)13.3(a)13.3(t)-2(e)13.3( wo)14.5(r)11.9(d)0.8( bounda)13.3(r)11.9(ie)27(s)13.1(.)-2.6( )13.7(+ )13.7(indi)11.7(c)13.3(a)-0.4(t)11.7(e)27(s a )]TJ 0 -1.137 TD 0.006 Tc -0.0094 Tw [(m)16.9(o)12.8(r)10.2(phe)11.6(me)11.6( b)-14.5(o)12.8(unda)11.6(r)10.2(y)12.8(.)23.1( )]TJ ET 305.041 608.679 21.6 -1.44 re f 326.641 608.679 1.32 -1.44 re f 327.961 608.679 204.48 -1.44 re f BT /F7 1 Tf 10.7452 0 0 10.7452 318.2409 550.5988 Tm 0 Tc 0 Tw ()Tj /F9 1 Tf 0.4579 0 TD ( )Tj /F5 1 Tf 0.7594 0 TD -0.0087 Tc 0.1384 Tw [(Fo)-11.3(r )11.2(l)-21.1(e)-11.4(xi)-9.9(c)-11.4(on wor)-21.9(d)11.1(s,)-15.6( w)9.7(o)-11.3(r)-10.7(d)-0.1( bo)-11.3(un)-11.3(d)-11.3(a)-11.4(ri)-9.9(es ar)-10.7(e )11.2(d)-11.2(e)-11.4(-)]TJ 0 -1.1503 TD 0.0023 Tc 0 Tw [(tec)10.8(t)1.1(ed)10.9(.)-4.6( )]TJ /F7 1 Tf -1.2173 -1.2061 TD 0 Tc ()Tj /F9 1 Tf 0.4579 0 TD ( )Tj /F5 1 Tf 0.7594 0 TD 0.0022 Tc 0.4179 Tw [(F)11(o)-0.4(r)11.3( )-11.1(m)9.6(o)10.8(rph)10.8(o)10.8(l)1(og)10.8(icall)-10.2(y)33.2( de)10.7(ri)12.2(v)10.8(e)-0.5(d w)20.6(o)-0.4(rds)11.5(,)6.5( th)10.8(ei)12.2(r)11.3( )]TJ 0 -1.2061 TD -0.0084 Tc -0.0182 Tw [(mo)-11(r)-10.4(p)-11(ho)-11(l)-9.6(o)-10.9(gi)-9.6(ca)-11.1(l)-9.6( pa)-11.1(tt)-9.6(e)-11.1(r)0.7(n)-10.9(s)0.9( )-11.1(a)-11.1(r)0.7(e )11.2(d)-11(e)-11.1(t)-9.6(e)0.1(c)-11.1(t)-9.6(ed,)-15.3( e.)-15.3(g. )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 506.4009 512.3188 Tm 0.0027 Tc 0 Tw (!")Tj -18.0603 -1.3245 TD 0 Tc (#)Tj /F5 1 Tf 10.7452 0 0 10.7452 341.0409 499.4788 Tm -0.0088 Tc 0.1385 Tw [( )-10.8(f)0.3(r)-10.8(i)-10(en)-11.4(d)-11.4(+)-14.4(s i)-10(s)0.5( d)-11.4(e)-11.5(ri)-21.2(v)11(e)-11.5(d )-11.2(b)-22.5(y)11( a)-11.5(ffi)-10(xa)-11.5(t)-10(i)-21.2(on o)-11.4(f)11.5( )-11.2(t)-21.2(h)11(e )]TJ -0.9046 -1.195 TD 0.0024 Tc [(plur)11.5(al)12.4( af)11.5(f)11.5(i)-10(x)11( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 384.9609 486.6388 Tm 0 Tc 0 Tw (#)Tj /F5 1 Tf 10.7452 0 0 10.7452 394.4409 486.6388 Tm 0.0023 Tc 0.1386 Tw [( t)-10.1(o)22.1( )-11.1(the)10.8( n)10.9(oun)10.9( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 454.2009 486.6388 Tm 0.0027 Tc 0 Tw (!")Tj /F5 1 Tf 10.7452 0 0 10.7452 473.4009 486.6388 Tm 0.0142 Tc 0.1267 Tw [( \(M)32.1(A_)22.8(S)23( i)13(n)11.6(-)]TJ -13.2227 -1.195 TD -0.0083 Tc 0.1827 Tw [(d)-10.9(i)-9.5(c)-11(a)0.2(t)-9.5(e)-11(s a s)-10.2(u)-10.8(ffi)-9.5(xa)-11(t)-9.5(i)-20.7(on p)-10.9(a)0.2(t)-9.5(t)-20.7(e)11.3(r)-10.3(n\))-10.3(, )-11.1(an)-10.9(d)11.5( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 486.2409 473.7988 Tm 0.0274 Tc 0 Tw (\)\)**)Tj /F5 1 Tf 10.7452 0 0 10.7452 525.7209 473.7988 Tm 0 Tc ( )Tj -18.0919 -1.1838 TD -0.0086 Tc 0.1495 Tw [()-10.6(h)-11.2(a)-11.3(ppi)-21(l)-21(y)22.4()-10.6( i)-9.8(s)0.7( )-11.1(a r)-10.6(e)-11.3(du)-11.1(p)-11.2(l)1.4(i)-9.8(c)-11.3(at)-9.8(i)-9.8(on )-11.1(o)-11.2(f)11.7( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 468.8409 461.0788 Tm 0.0027 Tc 0 Tw (\)*)Tj /F5 1 Tf 10.7452 0 0 10.7452 488.2809 461.0788 Tm 0.0024 Tc 0.1385 Tw [( ha)10.9(p)-0.2(py)33.3()-10.8( )]TJ -14.6075 -1.1503 TD 0.1607 Tw [(\(M)9.2(R_)11.1(A)9.8(A)-1.4(BB)10.6( ind)11.1(i)1.3(ca)11(tes)11.8( )-11.2(a)11(n)0( A)9.8(A)-12.6(B)10.6(B)10.6( redup)11.1(l)1.3(i)12.5(ca-)]TJ 0 -1.1391 TD 0.0022 Tc -0.0065 Tw [(tion)10.8( pat)12.2(t)-10.2(e)10.7(r)0.2(n\))11.3(.)-4.7( )]TJ /F7 1 Tf -1.2173 -1.2173 TD 0 Tc 0 Tw ()Tj /F9 1 Tf 0.4579 0 TD ( )Tj /F5 1 Tf 0.7594 0 TD -0.0084 Tc 0.462 Tw [(Fo)-11(r )-11.1(fa)-11.1(ct)-9.6(o)-11(i)-9.6(ds, t)-9.6(h)-11(ei)-9.6(r )11.2(t)-31.9(y)22.6(pe)-11.1(s)-10.3( a)-11.1(nd no)-11(r)-10.4(m)-1(al)-9.6(i)-20.8(z)0.1(e)-11.1(d)11.4( )]TJ 0 -1.1503 TD -0.0086 Tc 0.0936 Tw [(fo)-11.2(r)-10.6(m)-1.2(s a)-11.3(r)0.5(e de)-11.3(t)-9.8(e)-0.1(c)-11.3(t)-9.8(e)-11.3(d)11.2(,)-15.5( )11.1(e.)-15.5(g. 12)-11.2(:3)-11.2(0 i)-9.8(s)0.7( )11.1(t)-9.8(h)-11.2(e )11.1(n)-11.1(o)0(r)-10.6(m)-1.2(a)-11.3(l)-9.8(-)]TJ 0 -1.1838 TD 0.0023 Tc 0.0716 Tw [(ized)10.9( f)11.4(o)-0.2(rm)20.9( of)22.6( )-11.1(th)10.9(e)10.8( t)12.3(i)1.1(me)21.9( )-11.1(ex)22.1(pr)11.4(essio)10.9(n)10.9( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 477.1209 398.3188 Tm 0.0027 Tc 0 Tw ($%&'$)Tj -15.0399 -1.3369 TD 0 Tc (\()Tj /F5 1 Tf 10.7452 0 0 10.7452 341.0409 385.3588 Tm 0.0022 Tc 0.0047 Tw [( \()11.3(T)-12.2(I)22.5(M)-2.2(E)10.1( ind)22(i)-10.2(ca)10.7(tes)11.5( )11.2(a)10.7( )-11.1(t)12.2(i)1(m)9.6(e)10.7( )-11.1(e)10.7(x)22(pressi)-10.2(o)22(n)-0.3(\))11.3(.)-15.8( )]TJ /F7 1 Tf -2.1219 -1.2173 TD 0 Tc 0 Tw ()Tj /F9 1 Tf 0.4579 0 TD ( )Tj /F5 1 Tf 0.7594 0 TD 0.002 Tc 0.1277 Tw [(F)10.8(o)-0.6(r)11.1( nam)9.4(e)-0.7(d)10.6( )11.2(ent)12(itie)10.5(s)11.3(,)6.3( t)-10.4(h)10.6(e)10.5(i)0.8(r)11.1( t)12(y)21.8(pes are)10.5( d)10.6(e)-0.7(te)10.5(cte)10.5(d)10.6(,)6.3( )]TJ 0 -1.1838 TD 0.0048 Tc 0 Tw [(e.g)24.6(.)-2.1( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 351.1209 359.5588 Tm 0.0027 Tc (,-.)Tj /F5 1 Tf 10.7452 0 0 10.7452 380.2809 359.5588 Tm 0.0021 Tc 0.1499 Tw [( L)21.2(i Ju)10.7(n)10.7(s)0.2(heng)10.7()11.2( )11.1(is)11.4( a)10.6( per)11.2(s)0.2(on)10.7( n)10.7(a)-0.6(m)9.5(e)10.6( )]TJ -4.5565 -1.1503 TD -0.0085 Tc 0.0154 Tw [(\()-10.5(P)-10.9(N )11.2(i)-20.9(ndi)-9.7(c)-11.2(a)0(t)-20.9(e)11.1(s)-10.4( a p)-11(e)-0.1(r)-10.5(s)-10.4(on n)-11.1(a)-11.2(m)10.1(e)-11.2(\).)-15.4( )]TJ -2.4458 -1.4183 TD 0.0024 Tc 0.1943 Tw [(I)22.7(n)-0.2( o)11(u)-0.2(r )11.2(s)-10.6(y)33.3(st)-10(e)10.9(m)-1.3(,)6.7( w)20.8(e)-0.3( us)11.7(e)10.9( a)10.9( )22.3(unified)11( )22.3(appr)11.5(oach)11( )22.3(t)-10(o)11( )11.2(de-)]TJ 0 -1.1503 TD 0.0023 Tc 0.3173 Tw [(tec)10.8(t)1.1(i)-10.1(n)10.9(g)22.1( )-11.1(an)10.9(d)10.9( pro)10.9(c)10.8(es)11.6(si)-10.1(ng)33.3( )-11.1(th)10.9(e ab)10.9(ov)10.9(e)10.8( fo)10.9(ur)11.4( t)-10.1(y)33.2(pes of)22.6( )]TJ 0 -1.1391 TD -0.0085 Tc 0.261 Tw [(w)9.9(o)-11.1(r)-10.5(d)-11.1(s)-10.4(.)-4.2( Th)-11.1(i)-20.9(s)0.8( )11.1(a)-11.2(p)-11.1(pr)-10.5(o)-11.1(a)0(c)-11.2(h)11.3( i)-20.9(s)0.8( )11.1(b)-11.1(a)-11.2(s)-10.4(e)-11.2(d on t)-9.7(h)-11.1(e i)-9.7(m)-1.1(pr)-10.5(o)-11.1(v)0.1(e)-11.2(d)11.3( )]TJ 0 -1.1503 TD -0.0084 Tc 0.0153 Tw [(s)-10.3(o)-11(ur)-21.6(c)11.2(e)-11.1(-)-10.4(c)-11.1(ha)-11.1(n)-10.9(n)0.2(e)-11.1(l)1.6( mo)-11(d)-10.9(e)0.1(l)-9.6(s)0.9( de)-11.1(sc)-11.1(r)-10.4(i)-20.8(be)-11.1(d)11.4( )-11.1(bel)-20.8(o)0.2(w.)-15.3( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 305.0409 269.9188 Tm 0 Tc 0 Tw (4)Tj /F2 1 Tf 0.4932 0 TD ( )Tj /F3 1 Tf 1.8596 0 TD -0.0103 Tc 0.0274 Tw [(I)-22(m)0.8(p)-9.1(r)-8.1(ov)-24(e)-8.1(d)1.2( So)-13.7(u)-9.1(r)-8.1(c)-18.4(e)-8.1(-)-6.1(C)-17.8(ha)-13.7(n)-19.4(n)1.2(e)-8.1(l)-9.7( )10.2(M)-11.5(o)-13.7(de)-8.1(l)-9.7(s)-11.7( )]TJ /F5 1 Tf 10.7452 0 0 10.7452 305.0409 251.7988 Tm -0.0191 Tc 0 Tw [(Le)-21.8(t)-31.5( )]TJ /F6 1 Tf 1.6975 0 TD 0 Tc (S)Tj /F5 1 Tf 0.4914 0 TD 0.0021 Tc 0.1164 Tw [( b)10.7(e)10.6( a)10.6( )11.1(C)-12.1(h)10.7(i)-10.3(n)10.7(ese)21.7( )-11.2(s)11.4(e)-0.6(n)10.7(t)0.9(en)21.9(ce)10.6(,)-15.9( w)20.5(h)-0.5(ich)10.7( )11.1(is)11.4( a)10.6( ch)10.7(ara)10.6(c)-0.6(te)10.5(r)11.2( )]TJ -2.1889 -1.1391 TD -0.0089 Tc 0.1051 Tw [(s)-10.8(t)-10.1(ri)-21.3(ng.)-15.8( For)-10.9( al)-21.3(l p)-11.5(o)-0.3(s)-10.8(s)0.4(i)-10.1(b)-11.5(le)-11.6( wor)-10.9(d)-0.3( s)-21.9(e)-0.4(gme)-11.6(n)-11.5(ta)-11.6(t)-10.1(i)-10.1(o)-11.5(ns)-10.8( )]TJ /F6 1 Tf 17.969 0 TD 0 Tc 0 Tw (W)Tj /F5 1 Tf 0.8153 0 TD 0.0069 Tc 0.0893 Tw [(, w)25.3(e)4.2( )]TJ -18.7843 -1.1391 TD 0.002 Tc 0.0495 Tw [(w)20.4(i)0.8(l)-10.4(l)0.8( )11.1(choo)10.6(se)21.6( )-11.2(th)10.6(e)10.5( m)9.4(o)-0.6(st)12( lik)10.6(ely)21.8( on)10.6(e)10.5( )]TJ /F6 1 Tf 12.9435 0 TD 0 Tc 0 Tw (W)Tj 6.7744 0 0 6.7744 453.0009 232.1188 Tm (*)Tj /F5 1 Tf 10.7452 0 0 10.7452 456.361 227.3188 Tm -0.0083 Tc 0.0598 Tw [( wh)-10.9(i)-9.5(c)-11(h ac)-11(hi)-9.5(e)-11(v)11.5(e)-11(s)-10.2( )]TJ -14.0826 -1.1615 TD 0.002 Tc 0.2506 Tw [(the)10.5( h)10.6(i)-10.4(g)21.8(h)-0.6(es)11.3(t )11.2(cond)10.6(it)12(ion)10.6(a)-0.7(l)12( p)10.6(r)11.1(obab)10.6(ili)12(t)-21.5(y)44.1( )]TJ /F6 1 Tf 14.909 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (W)Tj /F5 1 Tf 0.8264 0 TD (|)Tj /F6 1 Tf 0.1675 0 TD (S)Tj /F5 1 Tf 0.5025 0 TD 0.002 Tc [(\):)-10.4( )]TJ /F6 1 Tf 1.1168 0 TD 0 Tc (W)Tj 6.7744 0 0 6.7744 512.5209 219.7588 Tm 0.0137 Tc (* )Tj /F5 1 Tf 10.7452 0 0 10.7452 519.6009 214.8388 Tm 0.0056 Tc (= )Tj -19.9681 -1.1391 TD 0.0025 Tc [(arg)11.1(m)9.9(ax)]TJ /F6 1 Tf 6.7744 0 0 6.7744 337.2009 201.1588 Tm 0 Tc (w)Tj /F5 1 Tf 10.7452 0 0 10.7452 341.4009 202.5988 Tm ( )Tj /F6 1 Tf 0.268 0 TD (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (W)Tj /F5 1 Tf 0.8376 0 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)11.2(ex)11(pres-)]TJ 0 -1.1391 TD -0.0087 Tc 0.0602 Tw [(s)-10.6(i)-21.1(ons)-10.6( be)-11.4(l)-9.9(o)-0.1(n)-11.3(g)-0.1( t)-21.1(o)11.1( a c)-11.4(l)1.3(a)-11.4(s)-10.6(s )11.1(T)-23.1(I)11.6(M)-13.1(E)-0.8(;)-9.9( a)-11.4(nd \()-10.7(4)-0.1(\))-10.7( )11.1(e)-11.4(a)-11.4(c)-0.2(h)-11.3( )11.1(t)-21.1(y)22.3(p)-11.3(e)-11.4( o)-11.3(f)0.4( )]TJ 0 -1.1503 TD 0.0825 Tw [(n)-11.2(a)-11.3(me)-11.3(d e)-11.3(n)0(t)-9.8(i)1.4(t)-21(i)1.4(e)-11.3(s)0.7( )11.2(i)-21(s)0.7( )11.2(d)-11.2(e)-11.3(fi)-9.8(n)-11.2(e)-0.1(d as a )11.2(c)-11.3(l)-9.8(as)-10.5(s,)-15.5( )11.2(e.)-15.5(g. a)-11.3(ll p)-11.1(e)-0.1(r)-10.6(s)-10.5(on )]TJ T* 0.0026 Tc 0.0824 Tw [(nam)10(e)-0.1(s )11.1(bel)12.6(ong)11.2( to)11.2( a)11.1( cl)12.6(ass)11.9( )-11.2(P)22.5(N)-1.3(.)6.9( We)11.1( t)12.6(h)0(er)11.7(ef)11.7(ore)11.1( conv)11.2(e)11.1(r)0.6(t)12.6( )]TJ 0 -1.1391 TD 0.0124 Tc 0.2513 Tw [(th)21(e)20.9( w)30.8(o)9.8(r)10.4(d)21( s)10.5(e)9.7(g)21(m)19.8(e)9.7(n)21(ta)20.9(t)11.2(i)22.4(o)9.8(n)21( )]TJ /F6 1 Tf 10.0957 0 TD 0 Tc 0 Tw (W)Tj /F5 1 Tf 0.8264 0 TD 0.0124 Tc 0.229 Tw [( in)21(to)21( a)20.9( )-22.3(w)30.8(o)9.8(r)10.4(d)9.8( )-11.2(c)9.7(l)22.4(a)9.7(s)10.5(s)21.7( )-11.2(s)10.5(e)9.7(-)]TJ -10.9221 -1.1391 TD 0.0026 Tc 0 Tw [(quenc)11.1(e)11.1( )]TJ /F6 1 Tf 3.0823 0 TD 0 Tc (C)Tj /F5 1 Tf 0.6589 0 TD 0.0019 Tc 0.005 Tw [(.)-5( )11.2(E)9.8(q)10.5(.)-5( 1)10.5( c)10.4(a)-0.8(n)10.5( t)11.9(h)-0.7(en)10.5( b)10.5(e)10.4( )11.2(r)-11.3(e)-0.8(w)20.3(r)-0.1(itten)10.5( )11.2(as: )]TJ 11.1436 0 0 11.1436 199.4409 455.9188 Tm 0 Tc 0 Tw (\))Tj -1.1092 0 TD (|)Tj -1.1415 0 TD (\()Tj -1.023 0 TD (\))Tj -1.0661 0 TD (\()Tj -2.5629 0 TD -0.0026 Tc (max)Tj -1.4538 0 TD -0.0009 Tc (arg)Tj 7.4287 0 0 7.4287 89.641 460.9588 Tm 0 Tc (*)Tj /F6 1 Tf 11.1436 0 0 11.1436 191.4009 455.9188 Tm (C)Tj -1.1522 0 TD (S)Tj -1.0122 0 TD (P)Tj -1.1199 0 TD (C)Tj -0.9692 0 TD (P)Tj -5.6643 0 TD (C)Tj 7.4287 0 0 7.4287 121.321 446.0788 Tm (C)Tj /F7 1 Tf 11.1436 0 0 11.1436 97.561 455.9188 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 205.5609 453.1588 Tm 0.018 Tc (. )Tj 6.79 0.3685 TD 0.0023 Tc (\(2\))Tj ET q 291.001 454.479 5.28 12.36 re W n BT 10.7452 0 0 10.7452 291.0009 457.1188 Tm 0 Tc ( )Tj ET Q BT 10.7452 0 0 10.7452 70.201 424.1188 Tm 0.0022 Tc -0.04 Tw [(E)-12.2(q)10.8(.)6.5( 2)10.8( is)11.5( the)10.7( ba)10.7(si)12.2(c )-11.2(f)11.3(o)10.8(rm)9.6( of)22.5( )-11.2(th)10.8(e )11.2(sour)11.3(ce-)11.3(chan)22(nel)12.2( )-11.2(m)9.6(o)-0.4(d)10.8(e)-0.5(ls)22.7( )]TJ 0 -1.1503 TD -0.0083 Tc -0.0407 Tw [(f)-10.3(o)0.3(r)-10.3( C)-11.4(h)-10.9(i)-9.5(n)0.3(e)-11(s)-10.2(e )-11.2(w)10.1(o)-10.9(r)-10.3(d)-10.9( se)-11(gme)-11(n)-10.9(t)-9.5(a)-11(ti)-20.7(on. T)-22.7(h)0.3(e )-11.2(mo)-10.9(de)-11(l)-9.5(s)-10.2( )11.1(a)-11(s)-10.2(s)-10.2(u)-10.9(me)11.3( )]TJ T* 0.0022 Tc 0.1052 Tw [(t)-10.2(h)10.8(at a)10.7( C)10.3(h)-0.4(in)10.8(ese)10.7( sen)10.8(t)1(en)10.8(ce)10.7( )]TJ /F6 1 Tf 10.0064 0 TD 0 Tc 0 Tw (S)Tj /F5 1 Tf 0.4914 0 TD -0.0088 Tc 0.1162 Tw [( i)-10(s)0.5( )-11.1(ge)-11.5(n)-11.4(e)-0.3(r)-10.8(a)-11.5(te)-11.5(d a)-11.5(s)0.5( )-11.1(fol)-10(l)-21.2(ows)-10.7(:)1.2( )]TJ -10.4978 -1.1391 TD 0.0031 Tc 0.0149 Tw [(First)13.1(,)7.4( a)11.6( )11.1(p)11.7(e)0.4(rs)12.4(on)22.9( ch)11.7(oo)11.7(ses)12.4( )22.3(a)11.6( se)11.6(q)11.7(u)0.5(ence)11.6( )11.1(of)23.4( )11.1(co)11.7(ncep)11.7(ts)12.4( )22.3(\()-10.1(i)13.1(.e)11.6(.,)18.6( )]TJ T* -0.0086 Tc 0.1606 Tw [(wor)-21.8(d)0( cl)-21(as)-10.5(s)-10.5(e)-0.1(s )]TJ /F6 1 Tf 5.5951 0 TD 0 Tc 0 Tw (C)Tj /F5 1 Tf 0.6701 0 TD 0.0019 Tc 0.139 Tw [(\))11( to)21.7( )-11.1(o)10.5(u)-0.7(tpu)10.5(t)11.9(,)-5( ac)10.4(c)10.4(o)-0.7(rd)10.5(ing)21.7( )-11.1(to)10.5( th)10.5(e)10.4( prob-)]TJ -6.2651 -1.1503 TD 0.002 Tc -0.0286 Tw [(abili)12(t)-10.4(y)33( d)10.6(i)-10.4(st)12(ri)-10.4(b)21.8(u)-0.6(t)12(i)-10.4(on)21.8( )]TJ /F6 1 Tf 7.5606 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (C)Tj /F5 1 Tf 0.6589 0 TD 0.0017 Tc -0.0395 Tw [(\);)11.7( th)10.3(en )11.2(the)10.2( p)10.3(e)-1(rso)10.3(n)10.3( )-11.2(a)10.2(t)0.5(t)11.7(e)-1(m)9.1(p)-0.9(ts)11( to)10.3( )]TJ -9.1688 -1.1503 TD 0.0025 Tc 0.2054 Tw [(ex)11.1(press)11.8( e)11(ach)22.3( )11.2(conc)11(ep)11.1(t b)11.1(y)33.5( choo)11.1(s)11.8(i)-9.9(ng)22.3( a)11( )11.2(sequ)11.1(e)11(n)-0.1(ce)11( )11.2(of)11.6( )]TJ 0 -1.1391 TD 0.0022 Tc 0.0158 Tw [(char)11.3(act)12.2(ers)11.5(,)-4.7( acco)10.8(rd)10.8(ing)10.8( )-11.2(to)10.8( t)-10.2(h)10.8(e)10.7( )-22.4(p)10.8(r)0.2(o)10.8(b)-0.4(ab)10.8(il)12.2(i)-10.2(t)1(y)33.2( )-11.2(dist)-10.2(r)11.3(i)1(bu)10.8(tio)10.8(n)10.8( )]TJ /F6 1 Tf 0 -1.1503 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj /F5 1 Tf 0.5137 0 TD (|)Tj /F6 1 Tf 0.1675 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD -0.0067 Tc 0.0247 Tw [(\). )]TJ -1.0833 -1.1391 TD 0.0023 Tc -0.0066 Tw [(T)-12.1(h)-0.3(e)10.8( )11.2(sour)11.4(ce-)11.4(ch)10.9(an)10.9(nel)12.3( )-11.2(m)9.7(o)10.9(de)10.8(ls)11.6( )-11.2(ca)10.8(n)10.9( be)10.8( in)10.9(te)10.8(r)-10.9(p)10.9(re)10.8(t)-10.1(e)10.8(d)10.9( in)22.1( )]TJ -1.2285 -1.1391 TD 0.0018 Tc 0.0609 Tw [(anoth)10.4(e)-0.9(r)10.9( )11.2(w)9.1(a)-0.9(y)32.8( a)10.3(s)-0.1( f)10.9(o)10.4(llow)20.2(s)-0.1(: )]TJ /F6 1 Tf 9.917 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (C)Tj /F5 1 Tf 0.6701 0 TD -0.009 Tc 0.0605 Tw [(\) i)-10.2(s)0.3( )11.1(a st)-21.4(o)-11.6(c)-0.5(ha)-11.7(st)-21.4(i)-10.2(c)-0.5( mod)-11.6(e)-11.7(l )]TJ -11.5252 -1.1503 TD 0.002 Tc -0.0286 Tw [(estim)9.4(at)12(i)-10.4(n)10.6(g)10.6( th)10.6(e )11.2(p)10.6(r)0(oba)10.5(b)10.6(ili)12(t)-21.5(y)44.1( of)11.1( )11.2(w)9.3(o)10.6(r)-11.2(d)10.6( cla)10.5(s)0.1(s)11.3( se)10.5(q)10.6(u)-0.6(enc)10.5(e)10.5(.)6.3( I)11.1(t)]TJ /F6 1 Tf 20.5488 0 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf -20.5488 -1.1503 TD -0.0083 Tc 0.0822 Tw [(i)-20.7(n)0.3(d)-10.9(i)-9.5(ca)-11(t)-9.5(e)-11(s, gi)-9.5(ve)-11(n a )11.2(c)-11(o)-10.9(nt)-9.5(e)-11(x)0.3(t, ho)-10.9(w)10.1( )-11.1(l)-9.5(i)-9.5(k)0.3(e)-11(l)-9.5(y)22.7( a)-11( wor)-21.5(d)11.5( )-11.1(cl)-9.5(as)-10.2(s )]TJ 0 -1.1391 TD 0.0023 Tc 0.0381 Tw [(occur)11.4(s)11.6(.)6.6( )-11.1(F)11.1(o)10.9(r)11.4( ex)22.1(am)9.7(ple)10.8(,)-4.6( p)10.9(e)-0.4(rs)11.6(o)10.9(n)10.9( nam)9.7(e)-0.4(s)11.6( )11.2(ar)11.4(e)10.8( m)9.7(o)-0.3(r)11.4(e)10.8( lik)10.9(el)-10.1(y)22.1( )]TJ 0 -1.1838 TD 0.0021 Tc 0.0829 Tw [(t)-10.3(o)21.9( )-11.2(o)21.9(ccu)10.7(r)11.2( b)10.7(e)-0.6(f)11.2(o)-0.5(re)10.6( )11.1(a)10.6( t)12.1(itle)10.6( )11.1(such)21.9( as)11.4( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 204.0009 251.4388 Tm 0.0027 Tc 0 Tw (/0)Tj /F5 1 Tf 10.7452 0 0 10.7452 223.2009 251.4388 Tm -0.0081 Tc 0.0931 Tw [( )-10.1(p)0.5(r)-10.1(o)-10.7(fe)-10.8(s)-10(s)1.2(o)-10.7(r. S)-10.5(o)11.7( )]TJ /F6 1 Tf -14.239 -1.1503 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (C)Tj /F5 1 Tf 0.6589 0 TD 0.0021 Tc -0.0287 Tw [(\) )-11.1(i)12.1(s)11.4( )-22.3(a)10.6(l)0.9(so)10.7( r)-11.1(e)10.6(fer)11.2(r)0.1(ed)10.7( to)10.7( )-11.1(as)11.4( )]TJ /F6 1 Tf 8.7332 0 TD 0.0024 Tc -0.029 Tw [(c)10.9(ontex)10.9(t)12.4( m)-12.7(o)11(de)10.9(l)]TJ /F5 1 Tf 5.5281 0 TD -0.0067 Tw [( af)11.5(t)12.4(e)-0.3(rw)9.7(ard)11(s)0.5(.)17.9( )]TJ /F6 1 Tf -15.8695 -1.1503 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj /F5 1 Tf 0.5137 0 TD (|)Tj /F6 1 Tf 0.1675 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD -0.0088 Tc 0.0603 Tw [(\) )11.1(i)-21.2(s)0.5( )11.1(a ge)-11.5(n)-11.4(e)-0.3(r)-10.8(a)-11.5(ti)-10(ve mo)-11.4(de)-11.5(l )11.1(e)-11.5(s)-10.7(t)-10(i)-10(m)-1.4(a)-11.5(t)1.2(i)-21.2(n)-0.2(g)11( h)-11.4(o)-11.4(w)9.6( l)-10(i)-10(k)-0.2(e)-11.5(l)-21.2(y)11( )]TJ -2.3117 -1.1503 TD 0.1162 Tw [(a c)-11.5(h)-11.4(ar)-10.8(a)-11.5(c)-0.3(t)-10(e)-0.3(r )-11.1(st)-10(ri)-10(n)-11.4(g)11( i)-10(s)-10.7( g)11(e)-11.5(ne)-11.5(r)-10.8(a)-0.3(t)-21.2(e)-0.3(d gi)-10(ve)-11.5(n a w)9.6(o)-11.4(r)-10.8(d)-0.2( )11.2(c)-11.5(l)-10(as)-21.8(s.)6.7( )]TJ 0 -1.1838 TD 0.0024 Tc 0.1608 Tw [(For ex)11(am)9.8(p)11(l)-10(e)10.9(,)-4.5( the)10.9( )-11.2(c)10.9(h)-0.2(ar)11.5(act)12.4(e)10.9(r)0.4( )-11.2(s)11.7(t)1.2(ring)22.2( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 223.2009 201.6388 Tm 0.0274 Tc 0 Tw (,-.)Tj /F5 1 Tf 10.7452 0 0 10.7452 252.9609 201.6388 Tm -0.009 Tc 0.1834 Tw [( is)-10.9( mor)-11(e)-0.5( )]TJ -17.0086 -1.195 TD -0.0085 Tc 0.194 Tw [(l)-20.9(i)-9.7(ke)-11.2(l)-20.9(y)22.5( t)-9.7(o)-11.1( be )11.1(a)-11.2( pe)-11.2(r)-10.5(s)0.8(o)-11.1(n)-11.1( )11.1(n)-11.1(a)0(me t)-9.7(h)-11.1(an )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 220.2009 188.7988 Tm 0.0398 Tc 0 Tw (4-.)Tj /F5 1 Tf 10.7452 0 0 10.7452 250.2009 188.7988 Tm 0.002 Tc 0.1835 Tw [( L)9.9(i )11.1(Jun-)]TJ -16.7517 -1.195 TD -0.0086 Tc 0.2276 Tw [(s)-10.5(h)-11.2(e)-11.3(n)-11.2(g be)-11.3(ca)-11.3(u)-11.2(s)0.7(e )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 142.5609 175.9588 Tm 0 Tc 0 Tw (,)Tj /F5 1 Tf 10.7452 0 0 10.7452 152.8809 175.9588 Tm -0.0081 Tc 0.216 Tw [( )11.2(i)-20.5(s)1.2( a c)-10.8(o)0.5(mmo)-10.7(n)-10.7( )-11.1(fa)-10.8(mi)-9.3(l)-31.6(y)34( )-11.1(n)-10.7(a)-10.8(me i)-9.3(n)0.5( )]TJ -7.6946 -1.195 TD 0.0012 Tc 0.0503 Tw [(C)-13(h)21(i)-11.2(n)-1.4(a)9.7( w)19.6(h)-1.4(ile)9.7( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 126.121 163.1188 Tm 0 Tc 0 Tw (4)Tj /F5 1 Tf 10.7452 0 0 10.7452 135.7209 163.1188 Tm 0.0043 Tc 0.0584 Tw [( i)14.3(s)2.4( )22.3(not)14.3(. )11.2(S)13.1(o)12.9( )]TJ /F6 1 Tf 4.4336 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj /F5 1 Tf 0.5137 0 TD (|)Tj /F6 1 Tf 0.1787 0 TD (C)Tj /F5 1 Tf 0.6701 0 TD 0.002 Tc 0.0495 Tw [(\) )11.1(i)-10.4(s)11.3( a)10.5(l)0.8(so)10.6( re)10.5(ferr)11.1(ed )11.1(to)10.6( )]TJ -12.8318 -1.1391 TD 0.0027 Tc 0 Tw [(as)12( )]TJ /F6 1 Tf 1.0609 0 TD 0.0025 Tc -0.0403 Tw [(c)11(l)1.3(ass)11.8( m)-12.6(o)22.3(del)]TJ /F5 1 Tf 4.6346 0 TD -0.0291 Tw [( af)11.6(terw)9.8(ard)22.3(s)0.6(.)6.8( In)11.1( )-11.1(o)11.1(u)11.1(r)0.5( sy)33.5(stem)9.9(, w)20.9(e)-0.2( )-11.1(u)11.1(s)0.6(e)22.1( )-11.1(th)11.1(e)11( )]TJ 16.1598 38.2051 TD 0.2166 Tw [(im)9.9(prov)11.1(ed)22.3( so)11.1(urc)11(e)-0.2(-)11.6(c)-0.2(han)11.1(n)11.1(e)-0.2(l)12.5( )11.2(m)9.9(o)-0.1(dels)11.8(, w)20.9(h)0(ic)11(h)11.1( )11.2(co)11.1(nta)11(i)1.3(ns)23( )]TJ 0 -1.1391 TD 0.0029 Tc -0.0407 Tw [(on)11.5(e)11.4( )-11.2(co)11.5(n)11.5(t)-9.5(e)11.4(x)11.5(t m)10.3(ode)11.4(l)12.9( \(i)12.9(.e)11.4(.,)7.2( )11.2(a)11.3( )-11.2(t)12.9(r)0.9(ig)11.5(ram)10.3( l)12.9(a)0.2(ng)11.5(uag)22.7(e)0.2( )-11.2(m)10.3(o)0.3(d)11.5(e)11.4(l i)-9.5(n)33.8( )]TJ 0 -1.1503 TD -0.0088 Tc -0.0178 Tw [(o)-11.4(u)-0.2(r)-10.8( c)-11.5(a)-0.3(s)-10.7(e)-0.3(\) a)-11.5(n)-11.4(d a s)-10.7(e)-0.3(t o)-11.4(f)0.3( c)-11.5(l)-10(as)-10.7(s mo)-11.4(de)-11.5(l)-10(s)-10.7( o)-11.4(f)11.5( di)-21.2(ffe)-11.5(r)-10.8(e)-11.5(n)-11.3(t)1.2( t)-21.2(y)22.2(pe)-11.5(s)-10.7(,)-15.7( )]TJ 0 -1.1391 TD 0.0023 Tc [(each)22.1( )-11.2(o)10.9(f)0.3( w)20.7(h)-0.3(ich)10.9( is)11.6( fo)10.9(r on)10.9(e)10.8( cla)10.8(s)0.4(s)11.6( )-11.2(o)10.9(f)11.4( )-11.2(w)20.7(o)-0.2(rds)11.6(,)6.6( )-11.2(as)11.6( )11.1(show)20.7(n i)-10.1(n)33.2( )]TJ 0 -1.1503 TD -0.0086 Tc 0.0266 Tw [(Fi)-21(gur)-10.6(e 2.)-15.5( )]TJ 1.2285 -1.1503 TD -0.0083 Tc 0.0933 Tw [(A)-12.2(l)1.7(t)-20.7(h)0.3(o)-10.9(u)-10.9(gh )11.1(E)-11.5(q)0.3(. 2)11.5( s)-10.2(ugge)-11(s)-10.2(t)-9.5(s t)-9.5(h)0.3(a)-11(t)1.7( )11.1(c)-11(l)-9.5(as)-10.2(s )-11.2(mo)11.5(d)-10.9(e)-11(l p)11.5(r)-21.5(ob)-10.9(-)]TJ -1.2285 -1.1391 TD 0.0024 Tc 0.0938 Tw [(ab)11(i)-10(l)12.4(i)12.4(t)-21.1(y)33.4( an)11(d con)11(t)1.2(ex)11(t m)9.8(o)-0.2(d)11(e)-0.3(l)12.4( )11.2(probab)11(il)12.4(i)-10(t)1.2(y)33.4( can)11( )-11.2(b)11(e)10.9( com)9.8(-)]TJ T* 0.002 Tc 0.3176 Tw [(bined)21.8( th)10.6(roug)10.6(h)21.8( )-11.1(s)11.3(i)0.8(m)9.4(p)-0.6(l)-10.4(e)21.6( m)9.4(u)10.6(ltipl)12(i)0.8(ca)10.5(tion)21.8(,)-4.9( )11.2(i)-10.4(n)10.6( p)10.6(r)0(a)10.5(c)-0.7(t)12(i)-10.4(c)10.5(e)10.4( )]TJ 0 -1.1503 TD 0.0022 Tc -0.0065 Tw [(som)9.6(e)-0.5( w)20.6(e)-0.5(ig)10.8(htin)10.8(g)10.8( )-11.2(i)12.2(s)11.5( des)11.5(i)1(rab)10.8(l)1(e)10.7(.)6.5( )11.2(T)-12.2(h)10.8(ere)10.7( )11.2(are)10.7( tw)20.6(o r)11.3(eas)11.5(ons)11.5(.)6.5( )]TJ 0 -1.1391 TD -0.0082 Tc 0.3724 Tw [(Fi)-20.6(r)-10.2(s)1.1(t,)-15.1( s)-10.1(o)-10.8(me )-11.2(c)11.4(l)-20.6(as)-10.1(s mo)-10.8(d)-10.8(e)0.3(l)-9.4(s)1.1( )-11.2(ar)-10.2(e p)-10.8(o)-10.8(o)0.4(r)-10.2(l)-20.6(y)22.7( e)-10.9(s)-10.1(t)-9.4(i)-9.4(m)-0.8(a)-10.9(t)1.8(e)-10.9(d)0.4(, )]TJ 0 -1.1503 TD -0.0087 Tc 0.0379 Tw [(o)-11.3(w)9.7(i)-9.9(n)-11.3(g t)-9.9(o)-0.1( t)-21.1(h)-0.1(e)10.9( )-11.2(s)-10.6(ub-)-10.7(op)-11.3(t)-9.9(i)-21.1(mal as)-10.6(s)-10.6(u)-11.3(mp)-11.3(ti)-21.1(o)-11.3(n)-0.1(s )-11.2(w)9.7(e)-0.2( ma)-11.4(ke)-11.4( fo)-11.3(r)11.6( )]TJ T* -0.0089 Tc 0.3731 Tw [(s)-10.8(i)-10.1(mp)-11.5(li)-21.3(ci)-10.1(t)-21.3(y)22.1( an)-11.5(d )11.1(th)-11.4(e )22.3(i)-10.1(n)-11.5(su)-11.5(ffi)-21.3(c)-11.6(i)-10.1(e)-11.6(n)-0.3(c)-22.8(y)33.2( o)-11.4(f)0.2( )22.3(t)-21.3(h)-11.5(e)10.7( )11.1(tr)-10.9(ai)-21.3(ni)-10.1(n)-11.4(g)10.9( )]TJ 0 -1.1391 TD 0.1944 Tw [(c)-11.6(o)-0.3(r)-22.1(pus.)-26.9( )11.1(C)-12(o)-11.5(mbi)-10.1(n)-11.5(in)-11.5(g t)-10.1(h)-11.5(e )11.1(c)-11.6(o)-0.3(n)-11.5(t)-10.1(e)-11.6(x)-0.3(t)-10.1( mo)-11.5(de)-11.6(l p)-11.4(r)0.2(o)-11.5(b)-11.5(a)-11.6(b)10.9(i)-21.3(li)-10.1(t)-32.4(y)33.2( )]TJ T* 0.002 Tc 0.3399 Tw [(w)20.4(i)0.8(t)-10.4(h)10.6( )-11.2(po)10.6(o)10.6(r)0(l)-10.4(y)33( esti)-10.4(m)9.4(a)10.5(ted)10.6( c)10.5(l)-10.4(a)21.6(s)-11(s)11.3( m)9.4(odel)12( )-11.2(p)21.8(r)-11.2(o)10.6(b)-0.5(a)10.5(b)-0.6(i)12(liti)12(es)11.3( )]TJ 0 -1.1503 TD 0.0029 Tc -0.0407 Tw [(acco)22.7(rdi)-9.5(n)11.5(g)11.5( to)11.5( )11.2(E)-11.5(q)22.7(. 2)11.5( )-11.2(w)21.3(o)0.3(u)11.5(l)-9.5(d)11.5( g)11.5(i)12.9(v)11.5(e)0.2( t)-9.5(h)11.5(e)11.4( con)11.5(t)1.7(ex)22.7(t)-9.5( m)10.3(o)0.3(d)11.5(e)0.2(l)12.9( too)22.7( )]TJ T* 0.0025 Tc 0.0602 Tw [(li)12.5(t)-9.9(t)12.5(le)11( )-11.2(w)20.9(e)-0.2(ig)11.1(ht)12.5(.)6.8( )-11.2(S)22.4(econd)22.3(, )11.2(a)11(s)11.8( s)11.8(e)11(en)11.1( i)12.5(n)11.1( F)11.3(i)1.3(g)11.1(u)-0.1(re)11( 2)11.1(,)-4.4( )11.2(t)12.5(h)-0.1(e)11( )11.2(cla)11(s)0.6(s)11.8( )]TJ 0 -1.1391 TD 0.0023 Tc 0.0381 Tw [(m)9.7(o)-0.3(d)10.9(e)-0.4(l)-10.1(s)11.6( of)11.4( d)10.9(i)1.1(ff)11.4(erent)12.3( w)20.7(o)-0.3(rd )11.2(classe)10.8(s )11.2(are)10.8( co)10.9(nst)12.3(r)0.3(uc)10.8(ted)10.9( )11.2(i)-10.1(n)22.1( )]TJ T* 0.0032 Tc 0.026 Tw [(dif)12.3(f)12.3(e)0.5(rent)13.2( )-11.2(w)21.6(a)-10.7(y)34.1(s)1.3( \(e)11.7(.g)11.8(. )11.2(nam)10.6(e)11.7( e)11.7(n)0.6(ti)13.2(t)-20.3(y)45.3( )-11.2(m)10.6(o)0.7(d)11.8(e)0.5(l)-9.2(s)12.5( )11.2(are)11.7( )]TJ /F6 1 Tf 17.6675 0 TD 0 Tc 0 Tw (n)Tj /F5 1 Tf 0.5026 0 TD -0.0081 Tc [(-gr)-10.1(a)-10.8(m )]TJ -18.17 -1.1503 TD -0.0084 Tc 0.0934 Tw [(mo)-11(de)-11.1(l)-20.8(s)0.9( tr)-10.4(ai)-20.8(ne)-11.1(d o)-11(n)0.2( c)-11.1(o)0.2(r)-10.4(p)-11(o)11.4(r)-21.6(a, a)-11.1(n)-10.9(d fa)-11.1(ct)-9.6(o)-10.9(i)-9.6(d mo)-10.9(d)-11(e)0.1(l)-9.6(s)0.9( ar)-10.4(e )]TJ 0 -1.1391 TD -0.0086 Tc 0.2165 Tw [(c)-11.3(o)0(m)-12.3(p)0(i)-21(l)1.4(e)-11.3(d)0( )-11.1(usi)-21(ng )-11.2(li)-21(n)-11.1(g)11.2(u)-11.2(i)-9.8(st)-21(i)-9.8(c)-0.1( kno)-22.3(w)9.8(l)-21(e)-11.3(dge)-11.3(\))-10.6(.)-15.5( T)-11.8(h)-11.2(er)-10.6(e)-11.3(f)0.5(o)-11.2(r)0.5(e, )]TJ 0 -1.1503 TD 0.0021 Tc 0.0048 Tw [(the)10.6( q)10.7(u)-0.5(an)21.9(t)-10.3(i)12.1(ti)-10.3(e)10.6(s)11.4( of)22.4( c)10.6(l)-10.3(a)10.5(s)0.2(s)11.4( m)9.5(o)-0.4(de)10.6(l)12.1( pr)11.2(obab)10.7(il)12.1(i)-10.3(t)12.1(ies)11.4( a)21.7(r)-11.1(e)10.6( )11.2(li)-10.3(k)21.9(e)-0.6(l)-21.4(y)44.2( )]TJ T* 0.0024 Tc 0.306 Tw [(to)11( )-11.2(h)11(a)-0.3(v)11(e)-0.3( )-11.2(v)22.2(a)-0.3(s)11.7(t)-10(l)-10(y)33.4( diff)11.5(eren)11(t)12.4( dy)22.2(nam)9.8(i)1.2(c rang)22.2(es)11.7( )-11.2(am)9.8(ong)22.2( )]TJ 0 -1.1391 TD -0.0086 Tc 0.183 Tw [(d)-11.2(i)-9.8(ffe)-11.3(r)-10.6(e)-11.3(n)-11.2(t)1.4( wor)-21.8(d)11.2( )11.2(cl)-21(as)-21.6(ses)-10.5(.)-4.3( )11.2(One w)9.8(a)-22.5(y)22.3( t)-9.8(o)-11.2( ba)-11.3(la)-11.3(n)-11.1(ce )11.2(t)-21(h)0(es)-10.5(e )]TJ T* 0.0018 Tc 0.0721 Tw [(prob)10.4(ab)10.4(ility)32.7( quan)10.4(ti)11.8(ti)-10.6(e)10.3(s)11.1( )11.2(is)11.1( to)10.4( )22.4(add)21.6( )-11.1(s)11.1(e)-0.9(v)21.6(e)-0.9(ra)10.2(l )]TJ /F6 1 Tf 15.8136 0 TD -0.0091 Tc 0.0718 Tw [(cl)-10.3(a)-11.7(ss m)-24.2(ode)-11.8(l )]TJ -15.8136 -1.1503 TD 0.0025 Tc 0 Tw [(we)11(igh)11.1(t)]TJ /F5 1 Tf 2.6468 0 TD 0 Tc ( )Tj /F6 1 Tf 0.3462 0 TD 0.0142 Tc (CW)Tj /F5 1 Tf 1.5077 0 TD 0.0023 Tc 0.1051 Tw [(,)6.6( )11.2(eac)10.8(h)10.9( f)11.4(o)-0.3(r)11.4( on)10.9(e)10.8( )11.2(w)20.7(o)-0.3(rd c)10.8(l)1.1(as)11.6(s)11.6(,)-4.6( t)12.3(o)10.9( ad)10.9(jus)11.6(t)12.3( th)10.9(e)10.8( )]TJ -4.5006 -1.1503 TD 0.0022 Tc 0.094 Tw [(clas)11.5(s)11.5( m)9.6(ode)10.7(l)12.2( p)10.8(r)0.2(oba)10.7(b)10.8(ili)12.2(t)-21.3(y)33.1( )]TJ /F6 1 Tf 9.8054 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj /F5 1 Tf 0.5137 0 TD (|)Tj /F6 1 Tf 0.1787 0 TD (C)Tj /F5 1 Tf 0.6701 0 TD 0.002 Tc 0.083 Tw [(\) t)-10.4(o)21.8( )]TJ /F6 1 Tf 1.7868 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj /F5 1 Tf 0.5026 0 TD (|)Tj /F6 1 Tf 0.1787 0 TD (C)Tj /F5 1 Tf 0.6701 0 TD (\))Tj /F6 1 Tf 6.7744 0 0 6.7744 482.5209 258.7589 Tm 0.0061 Tc (CW)Tj /F5 1 Tf 10.7452 0 0 10.7452 492.601 253.8388 Tm 0.0069 Tc 0.0893 Tw [(. 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1)10.8( )]TJ 0 -1.1838 TD 0.0023 Tc 0 Tw [(sh)10.9(ow)20.7(s)-10.7(,)6.6( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 124.921 443.4388 Tm 0.0027 Tc [($%)12.4(&'$)-12.3(\()]TJ /F5 1 Tf 10.7452 0 0 10.7452 183.2409 443.4388 Tm 0.002 Tc 0.1612 Tw [( is)11.3( a)10.5( )22.3(f)11.1(actoid)10.6( )11.2(\()11.1(t)-10.4(im)9.4(e\))11.1( )11.2(can-)]TJ -8.5769 -1.195 TD -0.0086 Tc 0.0378 Tw [(di)-21(dat)-21(e)-0.1( w)9.8(i)-21(t)-9.8(h)0( t)-9.8(h)0(e c)-11.3(l)-9.8(as)-10.5(s)-10.5( mo)-11.2(del)-9.8( pr)-10.6(o)-11.2(b)-11.2(a)-11.3(b)11.2(i)-21(li)-9.8(t)-21(y)33.5( )]TJ /F6 1 Tf 15.8583 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 271.6809 430.5988 Tm 0.0027 Tc ($%)Tj -18.6297 -1.3245 TD 0.0522 Tc [(&)12.4('$\()]TJ /F5 1 Tf 10.7452 0 0 10.7452 131.7609 417.7588 Tm -0.0088 Tc 0.2055 Tw [(|T)-23.2(IME)-23.2(\))0.3( =)-14.4(1)11(,)-15.7( )-11.2(and )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 207.4809 417.7588 Tm 0.0522 Tc 0 Tw ($%)Tj /F5 1 Tf 10.7452 0 0 10.7452 227.761 417.7588 Tm 0.0027 Tc 0.2052 Tw [( and)11.3( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 253.0809 417.7588 Tm 0.0398 Tc 0 Tw ('$)Tj /F5 1 Tf 10.7452 0 0 10.7452 273.2409 417.7588 Tm 0.0024 Tc 0.1943 Tw [( are)22( )]TJ -16.9528 -1.195 TD -0.009 Tc 0.0717 Tw [(a)-11.7(l)-10.2(s)-10.9(o)-0.4( )-11.2(fac)-11.7(t)-10.2(oi)-10.2(d \()-22.2(n)-0.4(u)-11.6(m)-1.6(b)-11.6(e)-0.5(r)-11(\))0.1( c)-11.7(a)-11.7(ndi)-10.2(d)-11.6(a)-11.7(te)-11.7(s,)-15.9( )-11.2(w)9.4(i)-10.2(t)-10.2(h)10.8( )]TJ /F6 1 Tf 15.8583 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 271.6809 404.9188 Tm 0.0027 Tc ($%)Tj /F5 1 Tf 10.7452 0 0 10.7452 91.0809 392.1988 Tm -0.0213 Tc 0.017 Tw [(|N)-25.2(U)-36.4(M)-14.6(\))-23.3( =)]TJ /F6 1 Tf 3.663 0 TD -0.0043 Tc 0 Tw ( P)Tj /F5 1 Tf 0.8599 0 TD 0 Tc (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 143.4009 392.1988 Tm -0.0097 Tc ('$)Tj /F5 1 Tf 10.7452 0 0 10.7452 162.8409 392.1988 Tm 0.0039 Tc 0.0141 Tw [(|)25.2(NUM)10.6(\))13( =)9.5(1)12.5( )]TJ /F7 1 Tf -7.9738 -1.2173 TD 0 Tc 0 Tw ()Tj /F9 1 Tf 0.4579 0 TD ( )Tj /F5 1 Tf 0.8376 0 TD 0.0025 Tc 0.0937 Tw [(Nam)9.9(e)-0.2(d)11.1( )11.2(en)11.1(tit)12.5(i)-9.9(e)11(s:)12.5( F)11.3(o)-0.1(r)11.6( e)11(ach)22.3( t)12.5(y)22.3(pe)11( )-11.2(o)11.1(f)0.5( na)11(me)11(d)11.1( )11.2(ent)12.5(i)-9.9(-)]TJ 0 -1.1503 TD -0.0091 Tc 0.1388 Tw [(t)-10.3(i)-10.3(e)-0.6(s,)-16( w)9.3(e)-0.6( u)-11.7(s)-11(e )11.2(a )11.2(s)-11(e)-0.6(t o)-11.7(f)11.2( gr)-11.1(a)-11.8(m)9.5(ma)-11.8(r)-11.1(s)-11( and st)-21.5(a)10.5(t)-21.5(is)-11(ti)-21.5(c)-11.8(a)-0.6(l )]TJ 0 -1.1391 TD -0.0087 Tc 0.0937 Tw [(mod)-11.3(e)-11.4(l)-9.9(s)-10.6( )11.1(t)-9.9(o)-0.1( ge)-11.4(ne)-11.4(r)-10.7(a)-11.4(t)-9.9(e)-0.2( )11.1(c)-11.4(a)-11.4(n)-11.3(d)11.1(i)-21.1(dat)-21.1(e)-11.4(s as d)-11.3(e)-0.2(s)-10.6(c)-11.4(ri)-9.9(b)-11.3(e)-11.4(d )11.1(i)-9.9(n)11.1( )]TJ 0 -1.1615 TD -0.0079 Tc 0.0259 Tw [(Se)-10.6(c)-10.6(t)2.1(i)-20.3(on 5)11.9(.)-25.9(2. )]TJ /F3 1 Tf 11.6798 0 0 11.6798 70.201 316.9588 Tm 0.0034 Tc 0 Tw [(5.)6.8(1)]TJ /F2 1 Tf 1.2534 0 TD 0 Tc ( )Tj /F3 1 Tf 1.1096 0 TD -0.0022 Tc 0.0091 Tw [(M)-13.7(o)4.6(rph)9.3(o)-5.6(lo)-5.6(gi)-11.9(c)10.3(a)-5.6(ll)-11.9(y deriv)-5.6(e)0(d )10.3(w)-9.7(o)-5.6(rd)9.3(s )]TJ /F5 1 Tf 10.7452 0 0 10.7452 70.201 293.0788 Tm 0.0024 Tc 0.1161 Tw [(I)11.5(n)11( our)11.5( s)-10.6(y)33.4(stem,)6.7( )11.1(the)10.9( m)9.8(o)11(rpho)11(log)22.2(i)-10(cal)12.4(l)-10(y)33.4( der)11.5(i)1.2(v)11(e)-0.3(d)11( w)20.8(o)-0.2(rds)11.7( )]TJ 0 -1.1503 TD -0.0067 Tw [(are)10.9( g)11(e)10.9(ne)10.9(ra)10.9(t)-10(e)-0.3(d)22.2( )11.2(us)11.7(ing)22.2( f)11.5(i)1.2(v)11(e)10.9( m)9.8(o)22.2(r)-10.8(p)11(hol)12.4(og)11(ical)12.4( )11.2(pa)22(t)-10(t)12.4(ern)11(s)0.5(:)12.4( )11.2(\(1)11(\))11.5( )]TJ /F3 1 Tf 0 -1.195 TD 0.0019 Tc 0 Tw [(affix)10.5(a)10.5(t)-11.3(ion)]TJ /F5 1 Tf 4.0986 0 TD 0.0012 Tc (: )Tj /TT1 1 Tf 9.6942 0 0 9.6942 122.1609 267.8788 Tm 0.0646 Tc (!"#)Tj ET 1 i 142.801 266.559 10.2 -0.48 re f BT /F5 1 Tf 10.7452 0 0 10.7452 153.0009 267.8788 Tm 0.0132 Tc 0.2058 Tw [( )11.1(\(f)22.3(r)11.2(i)12(e)21.7(n)10.6(d)21.8( -)33.5( p)33(l)0.8(u)10.6(r)22.3(a)10.5(l)]TJ ET 200.521 266.799 24.84 -0.6 re f BT 10.7452 0 0 10.7452 225.3609 267.8788 Tm 0.0021 Tc 0.2169 Tw [(\))11.2( f)11.2(riend)21.9(s)0.2(;)12.1( \()11.2(2)-0.5(\))11.2( )]TJ /F3 1 Tf -14.44 -1.1838 TD 0.0026 Tc 0 Tw [(redu)11.4(p)0.2(l)12.6(i)-9.8(ca)22.4(t)-10.6(i)1.4(on)]TJ /F5 1 Tf 5.7068 0 TD 0.0012 Tc (: )Tj /TT1 1 Tf 9.6942 0 0 9.6942 137.0409 255.1588 Tm 0.0027 Tc (\)*)Tj /F5 1 Tf 10.7452 0 0 10.7452 156.3609 255.1588 Tm 0.0023 Tc -0.0178 Tw [( h)10.9(appy)22.1( )]TJ /TT2 1 Tf 3.5625 0 TD 0 Tc 0 Tw (!)Tj /F5 1 Tf 0.9716 0 TD ( )Tj /TT1 1 Tf 9.6942 0 0 9.6942 207.601 255.1588 Tm 0.0027 Tc [(\)\)*)12.4(*)]TJ /F5 1 Tf 10.7452 0 0 10.7452 246.3609 255.1588 Tm 0.0023 Tc -0.0178 Tw [( ha)10.8(p)-0.3(p)10.9(i)12.3(l)-21.2(y)44.4()-10.9(;)1.1( )]TJ -16.3944 -1.195 TD 0.0132 Tc 0 Tw [(\(3)21.8(\))22.3( )]TJ /F3 1 Tf 1.4518 0 TD 0.0027 Tc [(m)9.3(erg)22.5(i)-9.7(n)11.5(g)]TJ /F5 1 Tf 3.529 0 TD 0.0012 Tc (: )Tj /TT1 1 Tf 9.6942 0 0 9.6942 129.8409 242.3188 Tm 0.0027 Tc (56)Tj /F5 1 Tf 10.7452 0 0 10.7452 149.1609 242.3188 Tm 0.0035 Tc 0.0257 Tw [( on)23.3( )-11.2(du)23.3(t)-20(y)34.5()-9.7( )11.2(+ )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 204.0009 242.3188 Tm 0.0027 Tc 0 Tw (76)Tj /F5 1 Tf 10.7452 0 0 10.7452 223.321 242.3188 Tm 0.0023 Tc 0.0269 Tw [( of)11.4(f)11.4( du)10.9(t)-10.1(y)33.3( )]TJ /TT2 1 Tf 4.4224 0 TD 0 Tc 0 Tw (!)Tj /TT1 1 Tf 9.6942 0 0 9.6942 281.2809 242.3188 Tm (5)Tj -21.7738 -1.3245 TD 0.0027 Tc (76)Tj /F5 1 Tf 10.7452 0 0 10.7452 89.641 229.4788 Tm 0.0022 Tc 0.1275 Tw [( o)10.8(n-)11.3(of)11.3(f)11.3( du)10.8(t)-10.2(y)33.2(; )11.2(\()-11(4)10.8(\) )]TJ /F3 1 Tf 7.8398 0 TD 0.0124 Tc 0.1396 Tw [(h)21.2(e)20.9(a)9.8(d)10( p)32.3(a)9.8(r)9.7(t)21.5(ic)32(le)]TJ /F5 1 Tf 5.6956 0 TD 0.0032 Tc 0.1153 Tw [( \(i)13.2(.e)11.7(.)7.5( ex)11.8(pres-)]TJ -15.3446 -1.195 TD 0.002 Tc 0.0495 Tw [(si)-10.4(o)10.6(n)10.6(s)11.3( th)10.6(at)12( )22.3(are)10.5( v)21.8(e)-0.7(r)11.1(b)10.6( +)18.8( )11.1(c)10.5(o)-0.6(m)9.4(p)-0.6(\))11.1(:)0.8( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 195.0009 216.6388 Tm 0 Tc 0 Tw (8)Tj /F5 1 Tf 10.7452 0 0 10.7452 204.7209 216.6388 Tm 0.0024 Tc 0.0268 Tw [( w)20.8(al)-10(k)22.2()-10.8( +)8( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 247.8009 216.6388 Tm 0.0027 Tc 0 Tw (9:)Tj /F5 1 Tf 10.7452 0 0 10.7452 267.1209 216.6388 Tm 0.0023 Tc 0.0381 Tw [( ou)10.9(t)1.1()11.4( )]TJ /TT2 1 Tf -18.3264 -1.1838 TD 0 Tc 0 Tw (!)Tj /F5 1 Tf 0.9828 0 TD ( )Tj /TT1 1 Tf 9.6942 0 0 9.6942 85.4409 203.9188 Tm 0.0274 Tc [(89)12.4(:)]TJ /F5 1 Tf 10.7452 0 0 10.7452 115.201 203.9188 Tm 0.0021 Tc 0.1834 Tw [( w)20.5(al)-10.3(k)21.9( out; a)10.6(n)10.7(d)10.7( \(5)10.7(\))11.2( )]TJ /F3 1 Tf 8.9008 0 TD 0.0015 Tc 0 Tw [(sp)10.3(lit)]TJ /F5 1 Tf 1.8315 0 TD 0.0034 Tc 0.1821 Tw [( )11.1(\(i)13.4(.e)11.9(.)7.7( a)11.9( se)11.9(t)13.4( of)12.5( )]TJ -14.9202 -1.1503 TD -0.0087 Tc 0.0491 Tw [(e)-11.4(x)-0.1(p)-11.3(r)-10.7(e)-11.4(s)-10.6(si)-9.9(o)-11.3(n)-11.3(s)0.6( t)-9.9(h)-0.1(a)-11.4(t)-9.9( ar)-10.7(e s)-10.6(e)-0.2(p)-11.3(a)-11.4(ra)-11.4(te)-11.4( wo)-11.3(r)-10.7(d)-0.1(s)-10.6( a)-11.4(t)1.3( )11.2(t)-21.1(h)-0.1(e )-11.1(s)-21.7(y)33.4(n)-11.3(t)-21.1(ac)-11.4(t)-21.1(i)1.3(c )]TJ 0 -1.195 TD 0.0124 Tc -0.039 Tw [(le)9.7(v)32.2(e)9.7(l)11.2( b)9.8(u)9.8(t)22.4( s)21.7(i)0(n)9.8(g)32.2(le)20.9( )-11.1(w)30.8(o)9.8(r)10.4(d)9.8(s)21.7( a)20.9(t)11.2( t)11.2(h)9.8(e)20.9( )-11.1(s)10.5(e)9.7(m)19.8(a)9.7(n)32.2(t)0(i)22.4(c)20.9( le)9.7(v)32.2(e)9.7(l)11.2(\))10.4(:)22.4( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 262.0809 178.7188 Tm -0.0097 Tc 0 Tw [(2;)-12.4(3)]TJ /F5 1 Tf 10.7452 0 0 10.7452 291.0009 178.7188 Tm 0 Tc ( )Tj -20.5488 -1.1838 TD 0.0026 Tc -0.0404 Tw [()-10.6(a)11.1(lrea)11.1(d)-11.1(y)44.7( )-11.2(ate)11.7(, w)21(h)0(ere)11.1( the)11.1( )11.2(bi-)11.7(c)11.1(hara)11.1(cte)11.1(r)11.7( )-11.2(w)21(o)0(rd )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 249.8409 165.9988 Tm 0.0027 Tc 0 Tw (23)Tj /F5 1 Tf 10.7452 0 0 10.7452 269.1609 165.9988 Tm 0.0024 Tc -0.0402 Tw [( ea)10.9(t)1.2()11.5( )]TJ -18.5162 -1.262 TD 0.0017 Tc 0.0052 Tw [(i)-10.7(s)11( sp)10.3(lit)11.7( b)-12(y)32.7( t)-10.7(h)10.3(e)10.2( p)10.3(a)-1(rt)11.7(icl)11.7(e)10.2( )]TJ /TT3 1 Tf 8.8449 0 TD 0 Tc 0 Tw (!)Tj /F5 1 Tf 0.9828 0 TD 0.0033 Tc 0.0036 Tw [( a)11.8(lre)11.8(a)0.6(d)-10.4(y)34.3(. )]TJ -8.5434 -1.1838 TD 0.0019 Tc 0.139 Tw [(I)22.2(t)-10.5( is)11.2( d)10.5(i)0.7(ff)11(icul)11.9(t)11.9( to)10.5( s)11.2(i)0.7(m)9.3(p)-0.7(l)-10.5(y)32.9( ex)10.5(tend)21.7( )-11.1(th)10.5(e)10.4( w)20.3(e)-0.8(ll-k)21.7(now)20.3(n)-11.8( )]TJ -1.2843 -1.1615 TD -0.0079 Tc 0.0036 Tw [(t)-20.3(e)-10.6(ch)-10.5(ni)-9.1(q)-10.5(u)0.7(e)-10.6(s)1.4( )11.2(f)-9.9(o)0.7(r)-9.9( )22.3(E)-11.1(n)-10.5(gl)-9.1(i)-9.1(s)-9.8(h)11.9( \(i.)-25.9(e)0.6(., fi)-9.1(ni)-20.3(t)-9.1(e)-10.6(-st)-9.1(a)0.6(t)-20.3(e)11.7( mo)-10.5(r)-9.9(p)-10.5(hol)-20.3(og)-10.5(y)23.1(\))-21.1( )]TJ 0 -1.1391 TD 0.0023 Tc 0.0492 Tw [(t)-10.1(o)22.1( )-11.2(Ch)10.9(ine)10.8(s)0.4(e)10.8( due)10.8( to)10.9( t)-10.1(w)20.7(o)10.9( )-11.2(r)11.4(eas)11.6(on)10.9(s.)6.6( )-11.2(F)11.1(i)1.1(r)11.4(s)0.4(t,)6.6( Ch)10.9(i)-10.1(n)10.9(e)10.8(s)-10.7(e)21.9( )-11.2(m)9.7(o)-0.2(r-)]TJ 21.8554 56.9001 TD 0.0021 Tc 0.2058 Tw [(m)9.5(o)-0.5(rph)10.7(o)-0.5(log)10.7(i)0.9(c)10.6(a)-0.6(l ru)10.7(l)-10.3(e)10.5(s a)10.6(r)-11.1(e)10.6( n)10.7(o)-0.5(t as)11.4( )-11.1(g)10.7(ene)10.6(r)0.1(al)12.1( as)11.4( )-11.1(th)10.7(ei)12.1(r)11.2( )]TJ 0 -1.1503 TD 0.0026 Tc 0.1494 Tw [(Eng)11.2(l)1.4(i)12.6(s)-10.4(h)22.4( co)11.2(unt)12.6(e)-0.1(rp)11.2(ar)11.7(ts)11.9(. F)11.4(o)11.2(r)11.7( )11.1(ex)11.2(am)10(ple,)6.9( )11.1(Eng)11.2(lis)11.9(h)11.2( pl)12.6(ura)11.1(l)12.6( )]TJ T* -0.0086 Tc 0.1718 Tw [(n)-11.2(o)0(u)-11.2(n)-11.2(s)0.7( )-11.2(c)-11.3(a)-11.3(n)0( be)-11.3( i)-9.8(n)0( )-11.2(ge)-11.3(n)-11.2(e)-11.3(r)-10.6(a)-0.1(l)-9.8( )-11.2(g)11.2(e)-11.3(ne)-11.3(r)-10.6(a)-0.1(t)-21(e)-0.1(d)-11.2( us)-10.5(i)-21(ng t)-9.8(h)-11.2(e )-11.2(r)-10.6(u)0(l)-9.8(e)-0.1( )]TJ 0 -1.1391 TD -0.0089 Tc -0.0289 Tw [()-10.9(n)-11.5(o)-11.5(un +)7.9( )-11.2(s )]TJ /TT2 1 Tf 3.8976 0 TD 0 Tc 0 Tw (!)Tj /F5 1 Tf 0.9716 0 TD -0.0087 Tc -0.0291 Tw [( pl)-9.9(ur)-10.7(a)-11.4(l)-9.9( )11.2(n)-11.3(o)-11.3(un.)-15.6( )11.2(B)-11.8(u)-0.1(t)-9.9( o)-11.2(n)-0.1(l)-21.1(y)22.3( a)-11.4( s)-10.6(m)-1.3(a)-11.4(l)1.3(l)-9.9( s)-10.6(u)-11.3(bs)-10.6(e)-11.4(t)1.3( )11.2(o)-11.2(f)0.4( )]TJ -4.8692 -1.1838 TD -0.0078 Tc 0.0147 Tw [(C)-10.9(h)0.8(i)-9(n)-10.4(e)-10.5(s)1.5(e )11.2(n)-10.4(o)-10.4(u)-10.3(n)12(s)1.5( c)-10.5(a)0.7(n)12( b)-10.3(e)0.7( )11.2(pl)-9(ur)-9.8(al)-9(i)-20.2(zed \(e.)-14.7(g)0.8(. )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 467.4009 676.7188 Tm 0.0027 Tc 0 Tw [(!")12.4(#)]TJ ET 486.721 675.279 9.72 -0.48 re f BT /F5 1 Tf 10.7452 0 0 10.7452 496.4409 676.7188 Tm -0.0089 Tc 0.0158 Tw [(\) us)-10.8(i)-10.1(n)-11.5(g)10.9( )]TJ -17.8127 -1.195 TD 0.0022 Tc 0.0605 Tw [(its)11.5( Ch)10.8(ine)10.7(s)0.3(e)10.7( co)10.8(un)10.8(terpa)21.8(r)-11(t)12.2( )11.2(no)10.8(u)-0.4(n)10.8( +)19( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 445.921 663.8788 Tm 0 Tc 0 Tw (#)Tj /F5 1 Tf 10.7452 0 0 10.7452 455.5209 663.8788 Tm ( )Tj /TT2 1 Tf 0.3239 0 TD (!)Tj /F5 1 Tf 0.9604 0 TD 0.0026 Tc 0.0489 Tw [( pl)-9.8(u)22.4(r)-10.6(a)22.2(l)-9.8( nou)11.2(n)11.2()11.7( )]TJ -15.2887 -1.195 TD 0.003 Tc 0.3612 Tw [(w)21.4(h)0.4(ereas)12.3( o)11.6(t)1.8(he)11.4(rs)12.3( \(e)11.5(.g)22.8(.)7.3( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 404.8809 651.0388 Tm 0.2131 Tc 0 Tw (<=)Tj /F5 1 Tf 10.7452 0 0 10.7452 428.6409 651.0388 Tm 0.0025 Tc 0.3506 Tw [( pum)9.9(pk)22.3(i)-9.9(n)0(s)]TJ ET 476.881 649.839 4.08 -0.6 re f BT 10.7452 0 0 10.7452 480.9609 651.0388 Tm [(\))11.5( canno)11(t)12.4(.)6.7( )]TJ -16.372 -1.1503 TD -0.0082 Tc 0.1937 Tw [(Se)-10.9(c)-10.9(o)-10.8(n)-10.8(d)0.4(, )11.1(t)-9.4(h)-10.8(e )11.1(o)-10.8(p)0.4(er)-21.4(a)11.4(t)-20.6(i)-9.4(o)-10.8(ns re)-10.9(qui)-20.6(r)-10.2(e)0.3(d b)-10.8(y)22.7( C)-11.3(h)0.4(i)-9.4(n)-10.8(es)-10.1(e mor)-10.2(-)]TJ T* 0.0022 Tc -0.0288 Tw [(ph)10.8(olog)10.8(ica)10.7(l)12.2( a)10.7(n)-0.3(aly)33.2(s)0.3(is su)22(ch)10.8( a)21.8(s)0.3( )22.4(copy)33.1(i)-10.2(n)10.8(g)10.8( in)10.8( )11.2(re)10.7(dupl)12.2(ic)10.7(at)12.2(i)-10.2(o)-0.3(n)22(,)-4.7( )]TJ 0 -1.1391 TD 0.002 Tc -0.0286 Tw [(m)9.4(e)-0.7(rg)10.6(ing)10.6( and)10.6( sp)10.6(li)12(tting)10.6(,)6.3( can)10.6(n)10.6(o)-0.6(t)12( )-11.1(be)10.5( )11.2(im)9.4(plem)9.4(en)10.6(ted)10.6( )-11.1(u)21.8(s)0.1(i)-10.4(n)-0.5(g)32.9( )]TJ 0 -1.1503 TD -0.009 Tc 0.0159 Tw [(t)-10.2(h)-11.6(e cu)-11.6(r)-11(r)0.1(e)-11.7(n)-11.6(t )-11.1(f)11.3(i)-10.2(n)-11.6(i)1(t)-21.4(e)-0.5(-)-11(s)-10.9(ta)-11.7(t)-10.2(e)-0.5( net)-21.4(w)-1.7(o)-11.6(r)-11(ks)]TJ 7.4287 0 0 7.4287 441.601 604.5988 Tm 0 Tc 0 Tw (3)Tj 10.7452 0 0 10.7452 445.3209 601.7188 Tm -0.0043 Tc 0.0112 Tw (. )Tj -11.7709 -1.1391 TD 0.0022 Tc 0.0828 Tw [(Our)11.3( so)10.8(lut)12.2(i)-10.2(o)10.8(n)10.8( i)-10.2(s)11.5( the)10.7( )-11.2(ex)10.8(te)10.7(nd)10.8(e)10.7(d)-0.4( l)-10.2(e)-0.5(x)22(i)-10.2(ca)10.7(li)12.2(zat)12.2(i)-10.2(o)10.8(n)10.8(.)-4.7( W)8.1(e)10.6( )]TJ -1.2843 -1.1391 TD 0.0023 Tc 0.2726 Tw [(sim)9.7(p)-0.3(l)-10.1(y)33.3( col)12.3(l)1.1(ec)10.8(t)12.3( a)10.8(ll )11.2(m)9.7(o)10.9(rpho)10.9(log)10.9(i)1.1(cal)12.3(l)-10.1(y)33.3( der)11.4(i)1.1(v)10.9(e)-0.4(d )11.2(w)9.6(o)10.9(r)-10.9(d)22.1( )]TJ 0 -1.1615 TD -0.0088 Tc 0.038 Tw [(fo)-11.4(r)-10.8(m)-1.4(s)-10.7( o)-11.4(f)11.5( )-11.2(th)-11.4(e a)-11.5(b)-11.4(ove )-11.2(fi)-10(ve)-11.5( )11.2(t)-21.2(y)22.2(p)-22.5(e)-11.5(s a)-11.5(n)-11.4(d )11.2(i)-10(n)-11.4(c)-11.5(o)-0.2(r)-10.8(p)-11.4(or)-10.8(at)-10(e t)-10(h)-0.2(e)-11.5(m)9.8( )]TJ 0 -1.1391 TD 0.002 Tc 0.0942 Tw [(into)10.6( t)12(h)-0.6(e)10.5( l)-10.4(e)10.5(x)10.6(i)-10.4(co)21.8(n)10.6(,)6.3( )-11.2(ca)10.5(lled)10.6( )]TJ /F6 1 Tf 9.7048 0 TD -0.0084 Tc 0.1046 Tw [(mor)-10.3(p)-10.9(h l)-9.6(e)-11.1(xi)-9.6(c)-11.1(o)-11(n)]TJ /F5 1 Tf 5.8184 0 TD 0.0029 Tc 0.0933 Tw [(.)7.2( Th)22.7(e)11.4( )-22.3(p)22.7(r)-10.3(o)11.5(ce-)]TJ -15.5233 -1.1391 TD 0.002 Tc 0.1389 Tw [(du)10.6(r)-11.2(e)21.6( inv)21.8(o)-0.6(lv)10.6(es )11.2(t)-10.4(h)21.8(r)-11.2(e)10.5(e)10.5( step)21.8(s)-11(:)12( )]TJ /F3 1 Tf 10.9333 0 TD 0.0027 Tc 0.1493 Tw [(\(1\))11.8( Cand)11.5(i)-9.7(d)11.5(a)11.3(t)0.7(e)11.2( )-11.2(gen)11.5(e)11.2(ra)11.3(-)]TJ -10.9333 -1.1503 TD 0.0021 Tc 0 Tw (tion)Tj /F5 1 Tf 1.664 0 TD 0.0023 Tc 0.0604 Tw [(.)6.6( I)11.4(t)1.1( )11.2(is)11.6( )-11.2(d)10.9(o)-0.3(n)10.9(e)10.8( b)-11.4(y)33.3( app)10.9(l)-21.2(y)33.3(i)1.1(ng)22.1( )-11.2(a )11.2(set)12.3( of)22.6( )-11.2(m)9.7(o)10.9(r)-10.9(p)22.1(holog)10.9(ic)10.8(al)12.3( )]TJ -1.664 -1.1391 TD 0.002 Tc 0.0942 Tw [(rule)10.5(s)11.3( to)10.6( both)10.6( th)10.6(e)10.5( )-11.2(w)9.3(o)10.6(r)-11.2(d)21.8( )-11.2(lex)10.6(i)12(con)21.8( )-11.2(a)10.5(n)-0.6(d)10.6( a)10.5( l)-10.4(a)10.5(r)-11.2(g)21.8(e)10.5( corpu)10.6(s)11.3(.)6.3( )]TJ 0 -1.1838 TD -0.008 Tc 0.1377 Tw [(Fo)-10.6(r)-10( )11.2(e)-10.7(x)0.6(a)-10.7(m)-0.6(p)-10.6(l)-9.2(e,)-14.9( t)-9.2(h)0.6(e)-10.7( )11.2(r)-10(u)0.6(l)-9.2(e)0.5( )-10(n)-10.6(oun + )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 443.6409 502.9588 Tm 0 Tc 0 Tw (#)Tj /F5 1 Tf 10.7452 0 0 10.7452 453.361 502.9588 Tm ( )Tj /TT2 1 Tf 0.3685 0 TD (!)Tj /F5 1 Tf 0.9828 0 TD -0.0087 Tc 0.1384 Tw [( p)11.1(l)-21.1(ur)-10.7(a)-11.4(l)1.3( no)-11.3(un)-11.2( )]TJ -15.1547 -1.195 TD 0.0022 Tc 0.1052 Tw [(w)20.6(ould g)10.8(e)10.7(nera)10.7(t)-10.2(e)10.7( ca)10.7(nd)10.8(ida)10.7(t)1(e)10.7(s)11.5( lik)10.8(e )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 444.481 490.1188 Tm 0.0027 Tc 0 Tw [(!")12.4(#)]TJ ET 463.801 488.679 9.72 -0.48 re f BT /F5 1 Tf 10.7452 0 0 10.7452 473.5209 490.1188 Tm 0.018 Tc (. )Tj /F3 1 Tf 0.6142 0 TD 0.0021 Tc 0.1388 Tw [(\(2)10.7(\))11.2( Sta)10.7(t)0.1(i)12.1(s)0.2(-)]TJ -16.2939 -1.1615 TD 0.0941 Tw [(tica)10.7(l)12.1( f)-11.1(i)12.1(lt)11.2(er)10.6(i)-10.3(n)10.9(g)]TJ /F5 1 Tf 5.5951 0 TD 0.0718 Tw [(.)6.4( )-11.1(F)10.9(o)-0.5(r)11.2( )11.2(each)10.7( c)10.6(a)10.6(n)-0.4(dida)10.6(te)10.6(,)6.4( w)9.4(e)-0.6( ob)21.9(t)-10.3(a)10.6(in)10.7( a)10.6( s)11.4(e)-0.6(t)12.1( )]TJ -5.5951 -1.1391 TD 0.0022 Tc 0.2839 Tw [(of)11.3( )11.2(stat)12.2(is)11.5(t)-10.2(i)1(c)10.7(a)-0.5(l)12.2( f)11.3(e)-0.5(a)10.7(t)1(ur)11.3(es)11.5( su)10.8(c)10.7(h)10.8( a)10.6(s)11.5( f)11.3(r)0.2(eque)10.7(n)10.8(c)-11.7(y)33.2(,)-4.7( m)9.6(u)-0.4(tu)10.8(al)12.2( )]TJ T* 0.161 Tw [(inf)11.3(o)-0.4(rm)9.6(at)12.2(i)-10.2(o)10.8(n)10.8(,)-4.7( l)12.2(e)-0.5(f)11.3(t/rig)10.8(ht)12.2( con)10.8(t)12.2(ex)10.8(t dep)22(e)-0.5(nden)22(c)-11.7(y)33.2( f)11.3(r)-11(o)10.8(m)9.6( a )]TJ 0 -1.1503 TD 0.0023 Tc 0.0492 Tw [(larg)10.9(e)10.8( c)10.8(o)-0.3(rpu)10.9(s)11.6(.)6.6( W)8.2(e)10.8( )11.1(t)-10.1(h)10.9(en)10.9( )11.1(use)10.8( )22.3(an)10.9( i)-10.1(n)10.9(fo)22.1(r)-10.9(m)9.7(at)12.3(ion)10.9( g)10.9(a)-0.4(in-)11.4(l)12.3(i)-10.1(k)22.1(e )]TJ 0 -1.1391 TD 0.0022 Tc 0.0382 Tw [(m)9.6(e)-0.5(tric)10.7( de)10.7(sc)10.7(ribe)10.7(d)22( )-11.1(in)10.8( )11.2(\()11.3(C)-12(h)10.8(i)1(en)10.8(,)6.5( 19)10.8(97)10.8(; )11.2(Ga)10.7(o)10.8( e)10.7(t)12.2( )-11.1(al)12.2(.)6.5(,)-4.7( )11.2(200)10.8(2)10.8(\))11.3( )]TJ 0 -1.1503 TD 0.0019 Tc 0.2395 Tw [(to)10.5( )-11.2(e)10.4(s)0(t)11.9(i)0.7(m)9.3(a)-0.8(t)-10.5(e)10.4( )11.2(how)20.3( )-11.2(l)11.9(i)-10.5(k)21.7(e)-0.8(l)-21.6(y)44( )-11.2(a)10.4( can)10.5(did)10.5(a)-0.8(te)10.4( is)11.2( to)10.5( fo)10.5(r)-11.3(m)20.5( a)10.4( )]TJ T* -0.0085 Tc 0.194 Tw [(mo)-11.1(r)-10.5(p)-11.1(ho)-11.1(l)-9.7(o)-11(gi)-9.7(ca)-11.2(l)-9.7(l)-20.9(y)22.4( )-11.2(de)-11.2(ri)-20.9(ved w)9.9(o)-11.1(r)-10.5(d)-11(,)-15.4( )11.1(a)-11.2(n)-11.1(d r)-10.5(e)-11.2(mo)-11.1(ve )-10.5(b)0.1(a)-11.2(d)0.1( )]TJ 0 -1.1391 TD 0.0023 Tc 0.0157 Tw [(can)10.9(di)12.3(dat)12.3(e)-0.4(s)11.6(.)-4.6( T)-12.1(h)10.9(e)10.8( )-22.4(b)10.9(a)10.8(sic ide)10.8(a)-0.4( behind)10.9( the)10.8( )-11.2(m)9.7(e)-0.4(tri)12.3(c)-0.4( i)-10.1(s)11.6( )-11.2(t)12.3(h)-0.3(at)23.4( )]TJ T* 0.0381 Tw [(a )11.2(Ch)10.9(ines)11.6(e w)9.6(o)10.9(r)-10.9(d)22.1( )-11.1(sh)10.9(o)10.9(u)-0.3(ld)10.9( a)10.8(p)-0.2(p)10.9(ear)11.4( as)11.6( a)10.8( sta)10.8(b)-0.3(le)10.8( s)11.6(e)-0.4(que)10.8(n)-0.3(c)10.8(e)10.7( )]TJ 0 -1.1503 TD 0.0021 Tc 0.1388 Tw [(in)10.7( )-11.1(t)12.1(h)-0.5(e)10.6( )-11.1(c)10.6(o)-0.5(rpu)21.9(s)11.4(.)-4.8( Th)10.7(at)12.1( i)-10.3(s)11.4(,)6.4( t)-10.3(h)10.7(e)10.6( com)9.5(pon)10.7(en)10.7(ts)11.4( )-11.1(w)9.4(ith)10.7(in)10.7( t)-10.3(h)10.7(e)21.7( )]TJ T* 0.0159 Tw [(w)20.5(o)-0.5(rd a)10.6(r)0.1(e)10.6( st)12.1(rong)21.9(l)-21.4(y)33.1( 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a )-11.1(gi)-9.7(ve)-11.2(n)11.3( )-22.3(na)-11.2(me )]TJ /F3 1 Tf 7.8733 0 TD 0 Tc 0 Tw (G)Tj /F5 1 Tf 0.7706 0 TD -0.0084 Tc 0.0823 Tw [(, a)-11.1(nd )-11.1(i)-9.6(s)0.9( o)-11(f)11.9( )-22.3(th)-11(e )-11.1(pa)-11.1(tt)-9.6(er)-10.4(n )]TJ /F3 1 Tf 9.0906 0 TD 0.0144 Tc 0 Tw [(F+)26(G)]TJ /F5 1 Tf 1.9655 0 TD -0.0155 Tc (. )Tj -20.3143 -1.1503 TD 0.0133 Tc [(Bo)33.1(th)21.9( )]TJ /F3 1 Tf 2.1889 0 TD 0 Tc (F)Tj /F5 1 Tf 0.6142 0 TD 0.0041 Tc 0.0028 Tw [( and)23.9( )]TJ /F3 1 Tf 1.9432 0 TD 0 Tc 0 Tw (G)Tj /F5 1 Tf 0.7706 0 TD 0.0028 Tc 0.0041 Tw [( a)11.3(r)0.8(e)11.3( )-11.1(o)11.4(f)11.9( one)22.4( )-11.1(o)11.4(r)11.9( )11.2(tw)10.1(o cha)11.3(r)0.8(ac)11.3(te)11.3(rs)12.1( lo)11.4(ng)11.4(.)7.1( )-11.1(\()11.9(2)0.2(\))11.9( )]TJ -5.5169 -1.1391 TD 0.0023 Tc 0.0492 Tw [(Fam)9.7(i)1.1(l)-21.2(y)44.4( )-11.2(n)10.9(a)-0.4(m)9.7(e)10.8( )-11.2(l)12.3(i)1.1(st:)12.3( W)8.2(e)10.8( only)33.3( consi)12.3(d)-0.3(er)11.4( P)11.1(N)9.6( c)10.8(a)-0.4(nd)10.9(ida)10.8(t)1.1(es)11.6( )]TJ 0 -1.1503 TD 0.002 Tc 0.0607 Tw [(t)-10.4(h)10.6(at beg)21.8(i)-10.4(n)10.6( )-11.2(w)20.4(ith)21.8( )-22.3(an)21.8( )]TJ /F3 1 Tf 7.6835 0 TD 0 Tc 0 Tw (F)Tj /F5 1 Tf 0.6031 0 TD 0.0019 Tc 0.072 Tw [( )11.2(s)11.2(t)-10.5(o)21.7(r)-11.3(ed)21.7( in)10.5( )11.2(the)10.4( f)22.2(a)-0.8(m)9.3(i)-10.5(ly)32.9( nam)9.3(e)10.4( l)11.9(i)-10.5(s)11.2(t)11.9( )]TJ -8.2865 -1.1391 TD 0.0027 Tc 0.0042 Tw [(\()-10.5(w)21.1(hich)11.3( con)22.5(t)-9.7(ai)12.7(ns)12( 37)11.3(3)11.3( en)11.3(tr)11.8(ies)12( in)11.3( ou)11.3(r)11.8( s)-10.3(y)33.7(st)-9.7(em)10.1(\))11.8(.)-4.2( )]TJ 1.2843 -1.1391 TD 0.0025 Tc 0.3059 Tw [(Gi)-9.9(v)11.1(e)11(n)11.1( a)11( P)11.3(N)9.8( cand)22.3(i)-9.9(d)11.1(a)11(t)-9.9(e)11(,)6.8( )11.2(w)20.9(h)-0.1(ich )11.2(i)-9.9(s)11.8( )11.2(a)11( cha)11(r)0.5(ac)11(te)11(r )]TJ -1.2843 -1.1615 TD 0.0023 Tc 0 Tw [(st)-10.1(r)11.4(i)1.1(ng)22.1( )]TJ /F6 1 Tf 2.7026 0 TD 0.0026 Tc (S)Tj /F5 1 Tf 0.8264 0 TD -0.0083 Tc 0.1938 Tw [(, )11.1(t)-9.5(h)0.3(e cl)-9.5(as)-10.2(s mo)-10.9(de)-11(l )11.1(p)-10.9(r)-10.3(o)-10.9(b)-10.9(a)-11(b)11.5(i)-20.7(li)-9.5(t)-20.7(y)33.8( )]TJ /F6 1 Tf 12.3628 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD 0.0026 Tc (S)Tj /F5 1 Tf 0.8376 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1787 0 TD 0.0032 Tc (PN)Tj /F5 1 Tf 1.2843 0 TD 0.0016 Tc 0.1728 Tw [(\) is)22.1( )]TJ -19.1416 -1.1391 TD 0.0021 Tc 0.0606 Tw [(com)9.5(puted)10.7( )11.2(b)-11.6(y)33.1( a)10.6( cha)10.6(r)0.1(a)10.6(c)-0.6(te)10.6(r)11.2( b)10.7(i)12.1(g)10.7(r)0.1(am)9.5( )-11.2(m)9.5(o)10.7(de)10.6(l)12.1( )-11.2(as)11.4( f)11.2(o)10.7(llo)10.7(w)9.4(s)0.2(: )]TJ T* 0.0023 Tc -0.0289 Tw [(\()-10.9(1)10.9(\))11.4( G)9.6(e)-0.4(ne)10.8(rat)12.3(e)10.8( the)10.8( f)11.4(a)-0.4(m)20.9(i)-10.1(l)-10.1(y)33.3( na)10.8(m)9.7(e)-0.4( )11.2(sub-)11.4(stri)12.3(ng)10.9( )]TJ /F6 1 Tf 16.0147 0 TD 0 Tc 0 Tw (S)Tj 6.7744 0 0 6.7744 247.6809 460.3588 Tm (F)Tj /F5 1 Tf 10.7452 0 0 10.7452 251.6409 461.9188 Tm -0.0064 Tc -0.0091 Tw [(, w)12(i)-7.6(t)-18.8(h)13.4( )11.1(t)-7.6(h)2.2(e )]TJ -16.8857 -1.1503 TD 0.0025 Tc 0 Tw [(probab)11.1(i)1.3(l)12.5(i)1.3(t)-9.9(y)33.5( )]TJ /F6 1 Tf 4.8133 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 137.4009 447.9988 Tm (F)Tj /F5 1 Tf 10.7452 0 0 10.7452 141.4809 449.5588 Tm (|)Tj /F6 1 Tf 0.1787 0 TD (F)Tj /F5 1 Tf 0.6142 0 TD 0.002 Tc 0.1835 Tw [(\);)-10.4( \(2\))11.1( G)9.3(e)-0.7(ne)10.5(rate)10.5( th)10.6(e)10.5( )-11.2(g)10.6(i)0.8(v)10.6(e)-0.7(n)21.8( )-11.2(nam)9.4(e)21.6( )]TJ -7.4266 -1.1391 TD 0.0023 Tc 0 Tw [(sub-)11.4(st)-10.1(r)11.4(i)1.1(ng)22.1( )]TJ /F6 1 Tf 4.6123 0 TD 0 Tc (S)Tj 6.7744 0 0 6.7744 125.1609 435.7588 Tm (G)Tj /F5 1 Tf 10.7452 0 0 10.7452 129.9609 437.3188 Tm 0.0023 Tc 0.3843 Tw [(,)6.6( w)20.7(i)1.1(t)12.3(h)10.9( )11.2(the)10.8( )33.5(probab)22.1(i)-10.1(l)12.3(i)1.1(t)-10.1(y)33.3( )]TJ /F6 1 Tf 10.0622 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 253.5609 435.7588 Tm (G)Tj /F5 1 Tf 10.7452 0 0 10.7452 258.4809 437.3188 Tm (|)Tj /F6 1 Tf 0.1787 0 TD (G)Tj /F5 1 Tf 0.7259 0 TD 0.0022 Tc 0.3732 Tw [(\) \(or)11.3( )]TJ /F6 1 Tf -18.4269 -1.1503 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj 6.7744 0 0 6.7744 85.8009 423.5188 Tm -0.0134 Tc (G1)Tj /F5 1 Tf 10.7452 0 0 10.7452 94.0809 424.9588 Tm 0 Tc (|)Tj /F6 1 Tf 0.1675 0 TD (G)Tj 6.7744 0 0 6.7744 103.8009 423.5188 Tm (1)Tj /F5 1 Tf 10.7452 0 0 10.7452 107.1609 424.9588 Tm -0.0083 Tc -0.0072 Tw [(\))-10.3(\))-10.3(;)-20.7( an)-10.9(d \()-10.3(3)0.3(\) G)-12.2(e)-11(ner)-21.5(a)0.2(te)-11( )11.1(t)-9.5(h)-10.9(e s)-10.2(e)-11(co)-10.9(nd gi)-9.5(ve)-11(n)-10.9( n)-10.9(a)-11(me, )]TJ -3.4397 -1.1503 TD 0.0018 Tc -0.0173 Tw [(w)9.1(ith t)-10.6(h)10.4(e)10.3( )-11.2(p)10.4(r)-0.2(ob)10.4(ab)10.4(ility)32.8( )]TJ /F6 1 Tf 8.0743 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 172.4409 411.1588 Tm -0.0134 Tc (G2)Tj /F5 1 Tf 10.7452 0 0 10.7452 180.7209 412.5988 Tm 0 Tc (|)Tj /F6 1 Tf 0.1899 0 TD (S)Tj 6.7744 0 0 6.7744 188.1609 411.1588 Tm -0.0134 Tc (G1)Tj 10.7452 0 0 10.7452 196.4409 412.5988 Tm 0.0069 Tc (,G)Tj 6.7744 0 0 6.7744 207.0009 411.1588 Tm 0 Tc (2)Tj /F5 1 Tf 10.7452 0 0 10.7452 210.3609 412.5988 Tm 0.0022 Tc -0.0177 Tw [(\).)6.5( For)11.3( ex)10.8(am)9.6(ple)10.7(,)-4.7( th)10.8(e)10.7( )]TJ -13.044 -1.1838 TD 0.2057 Tw [(g)10.8(e)-0.5(nerat)12.2(i)1(v)10.8(e)10.7( pro)10.8(b)-0.4(a)10.7(b)10.8(i)-10.2(l)12.2(it)-21.3(y)44.3( of)22.5( t)12.2(h)-0.4(e)10.7( s)11.5(t)1(ring)10.8( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 232.0809 399.8788 Tm 0.0522 Tc 0 Tw (,-.)Tj /F5 1 Tf 10.7452 0 0 10.7452 262.4409 399.8788 Tm -0.0086 Tc 0.2165 Tw [( gi)-9.8(ve)-11.3(n )]TJ -17.8908 -1.195 TD 0.002 Tc 0.0384 Tw [(t)-10.4(h)10.6(at )11.2(it i)12(s)11.3( )-11.1(a)10.5( P)10.8(N)-1.9( w)20.4(ould)10.6( be)10.5( es)11.3(t)12(i)-10.4(m)9.4(a)-0.7(ted)10.6( a)10.5(s)11.3( )]TJ /F6 1 Tf 15.0766 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 242.521 387.0388 Tm 0.0027 Tc (,-.)Tj /F5 1 Tf 10.7452 0 0 10.7452 271.6809 387.0388 Tm -0.0213 Tc [(|P)-23.7(N)-25.2(\))]TJ /F6 1 Tf 1.798 0 TD 0 Tc ( )Tj -20.5488 -1.1838 TD 0.0062 Tc -0.0105 Tw (= P)Tj /F5 1 Tf 1.5412 0 TD 0 Tc 0 Tw (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 90.361 374.3188 Tm (,)Tj /F5 1 Tf 10.7452 0 0 10.7452 100.201 374.3188 Tm (|)Tj /F6 1 Tf 0.1675 0 TD (F)Tj /F5 1 Tf 0.6254 0 TD (\))Tj /F6 1 Tf 0.335 0 TD (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 122.401 374.3188 Tm (-)Tj /F5 1 Tf 10.7452 0 0 10.7452 132.2409 374.3188 Tm (|)Tj /F6 1 Tf 0.1787 0 TD (G)Tj 6.7744 0 0 6.7744 141.9609 372.7588 Tm (1)Tj /F5 1 Tf 10.7452 0 0 10.7452 145.3209 374.3188 Tm (\))Tj /F6 1 Tf 0.335 0 TD (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 159.1209 374.3188 Tm (.)Tj /F5 1 Tf 10.7452 0 0 10.7452 168.9609 374.3188 Tm (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 170.7609 374.3188 Tm (-)Tj /F5 1 Tf 10.7452 0 0 10.7452 180.4809 374.3188 Tm (,)Tj /F6 1 Tf 0.268 0 TD (G)Tj 6.7744 0 0 6.7744 191.1609 372.7588 Tm (2)Tj 10.7452 0 0 10.7452 194.5209 374.3188 Tm (\))Tj /F5 1 Tf 0.3239 0 TD 0.018 Tc (. )Tj /F3 1 Tf 11.6798 0 0 11.6798 70.201 348.9988 Tm 0.0034 Tc [(5.)6.8(2.)6.8(2)]TJ /F2 1 Tf 2.0035 0 TD 0 Tc ( )Tj /F3 1 Tf 10.7452 0 0 10.7452 97.8009 348.9988 Tm 0.0028 Tc 0.0041 Tw [(Loca)11.4(ti)12.8(on)11.6( nam)9.4(e)0.1(s )]TJ /F5 1 Tf -2.5686 -1.6528 TD -0.0088 Tc 0.2725 Tw [(U)-23.9(n)-0.2(l)-10(i)-10(k)-0.2(e PN)-12.7(s,)-15.7( t)-10(h)-11.4(er)-10.8(e )11.1(a)-11.5(r)0.3(e )-11.2(n)-11.4(o)-0.2( )11.1(p)-11.4(a)-11.5(tt)-21.2(er)-10.8(n)-11.4(s)0.5( f)-10.8(o)11(r)-10.8( LN)-12.7(s.)-15.7( )11.1(W)-14.1(e)10.8( )]TJ 0 -1.1503 TD -0.0086 Tc 0.1383 Tw [(a)-11.3(s)-10.5(s)-10.5(u)-11.2(me )11.2(t)-21(h)0(at)-9.8( a L)10.5(N)-1.3( )-11.2(c)11(a)-11.3(n)-11.2(d)0(i)-9.8(d)-11.2(ate)-11.3( )11.2(i)-21(s)0.7( gen)-11.2(e)-0.1(r)-10.6(a)-0.1(t)-21(e)-0.1(d gi)-9.8(ve)-11.3(n )]TJ /F6 1 Tf 19.7224 0 TD 0.0026 Tc 0 Tw [(S)11.7( )]TJ /F5 1 Tf -19.7224 -1.1503 TD 0.002 Tc 0.0049 Tw [(\()-11.2(w)20.4(hich )22.4(is)11.3( l)12(e)-0.7(ss)11.3( )22.4(t)-10.4(h)-0.6(a)10.5(n)10.6( 1)10.6(0)10.6( ch)21.8(ara)10.5(c)-0.7(t)-10.4(e)21.6(r)-11.2(s)11.3( )11.2(lo)10.6(ng)10.6(\),)6.3( if)22.3( o)10.6(n)-0.6(e)10.5( o)10.6(f)0( )22.4(the)21.6( )]TJ 0 -1.1391 TD -0.0091 Tc -0.0175 Tw [(f)-11.1(o)-0.5(l)-21.5(l)-10.3(o)-11.7(w)9.3(i)-10.3(n)-11.7(g )11.2(c)-11.8(o)-11.7(nd)-11.7(it)-10.3(i)-21.5(ons is sat)-10.3(i)-10.3(s)0.2(fi)-21.5(e)-11.8(d)-0.5(:)-10.3( )22.4(\()-11.1(1)-11.7(\) )]TJ /F6 1 Tf 14.4847 0 TD 0.0026 Tc 0 Tw (S)Tj /F5 1 Tf 0.8264 0 TD 0.0022 Tc -0.0512 Tw [( i)-10.2(s)11.5( an)10.8( ent)12.2(r)-22.2(y)44.3( )-22.4(in)10.8( )]TJ -15.3111 -1.1503 TD 0.0026 Tc -0.0404 Tw [(t)-9.8(h)11.2(e)11.1( )-11.2(L)21.7(N)-1.3( )11.2(l)12.6(i)-9.8(s)11.9(t)12.6( \(w)21(hich)11.2( c)11.1(ont)12.6(ain)11.2(s)11.9( 3)11.2(0)0(,0)11.2(00)11.2( L)10.5(N)9.9(s\))11.7(; )11.2(\(2\))11.7( )]TJ /F6 1 Tf 17.701 0 TD 0 Tw (S)Tj /F5 1 Tf 0.8264 0 TD 0.0027 Tc -0.0517 Tw [( end)11.3(s)12( )]TJ -18.5274 -1.1391 TD 0.0025 Tc -0.0291 Tw [(i)-9.9(n)22.3( a)11( )11.2(k)11.1(e)-11.4(y)22.3(w)20.9(ord )11.2(i)-9.9(n)22.3( a)11( )22.4(120-)11.6(ent)12.5(r)-10.7(y)33.5( )11.2(L)10.4(N)-1.4( k)22.3(e)-11.4(y)22.3(w)9.8(ord )22.4(l)-9.9(i)12.5(st)12.5( s)11.8(u)-0.1(ch)11.1( )11.2(a)11(s)11.8( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 70.201 256.9588 Tm 0 Tc 0 Tw (>)Tj /F5 1 Tf 10.7452 0 0 10.7452 79.921 256.9588 Tm 0.0148 Tc 0.0032 Tw [( c)23.3(i)13.6(t)2.4(y)45.8()]TJ 7.4287 0 0 7.4287 105.961 259.8388 Tm 0 Tc 0 Tw (5)Tj 10.7452 0 0 10.7452 109.681 256.9588 Tm -0.0086 Tc 0.0155 Tw [(.)-26.6( T)-23(h)11.2(e)-11.3( )-11.1(pr)-21.8(oba)-11.3(b)-11.2(i)1.4(l)-9.8(i)-9.8(t)-21(y)22.4( )]TJ /F6 1 Tf 6.9687 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD 0.0026 Tc (S)Tj /F5 1 Tf 0.8376 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1675 0 TD 0.0024 Tc (LN)Tj /F5 1 Tf 1.2285 0 TD 0.0023 Tc 0.0269 Tw [(\))-10.9( )11.2(i)12.3(s)0.4( c)10.8(o)10.9(m)9.7(pute)10.8(d)10.9( by)22.1( )]TJ -13.8258 -1.1503 TD 0.0025 Tc -0.0068 Tw [(a )-11.2(ch)11.1(a)11(r)0.5(ac)11(t)-9.9(e)11(r big)11.1(r)0.5(am)21.1( )-22.3(m)9.9(o)11.1(de)11(l)12.5(.)-4.4( )]TJ 1.2285 -1.1838 TD -0.0086 Tc 0.0155 Tw [(C)-22.8(ons)-10.5(i)-21(d)0(er)-10.6( a)-11.3( )11.2(s)-10.5(t)-9.8(r)-10.6(i)-9.8(n)-11.2(g)0( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 159.6009 231.8788 Tm 0.0027 Tc 0 Tw [(?@4)12.4(A)]TJ /F5 1 Tf 3.9983 0 TD 0 Tc ( )Tj 10.7452 0 0 10.7452 200.881 231.8788 Tm 0.0032 Tc 0.0037 Tw [(W)9.1(us)12.5(ul)13.2(i)-9.2( )11.2(ri)-9.2(v)23(e)0.5(r)12.3()1.2(. I)12.3(t)2( is )11.2(a)22.8( )]TJ -12.1618 -1.2061 TD 0.0023 Tc 0.0827 Tw [(L)10.2(N)-1.6( ca)10.8(ndid)10.9(a)-0.4(t)12.3(e)10.8( bec)10.8(a)-0.4(u)10.9(s)11.6(e)10.8( )-11.2(i)12.3(t)12.3( en)10.9(ds)11.6( in)10.9( )11.1(a)10.8( )-11.2(L)21.4(N)9.6( )-11.2(k)22.1(e)-11.6(y)22.1(w)9.6(ord )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 281.4009 218.9188 Tm 0 Tc 0 Tw (A)Tj /F5 1 Tf 10.7452 0 0 10.7452 291.0009 218.9188 Tm ( )Tj -20.5488 -1.1503 TD 0.0022 Tc 0.3285 Tw [()-11(r)0.2(iv)10.8(er)11.3()11.3(.)-4.7( )22.3(Th)10.8(e)10.7( g)10.8(e)-0.5(n)10.8(e)10.7(r)-11(a)21.8(t)-10.2(i)1(v)10.8(e)10.7( )11.1(p)10.8(r)11.3(obabi)12.2(lit)-10.2(y)33.2( )11.1(of)22.5( th)10.8(e)10.7( s)11.5(t)1(r)11.3(i)1(ng)10.8( )]TJ 0 -1.1838 TD -0.0088 Tc 0.0715 Tw [(gi)-10(ve)-11.5(n)-11.4( it)-10( )11.2(i)-10(s)0.5( a L)10.3(N)-12.7( w)9.6(o)-11.4(u)-11.4(l)-10(d )11.2(b)-11.4(e)-0.3( )22.3(e)-11.5(s)-10.7(ti)-21.2(ma)-11.5(t)-10(e)-0.3(d as )]TJ /F6 1 Tf 15.9812 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 252.1209 193.8388 Tm 0.0027 Tc [(?@)12.4(4A)]TJ /F5 1 Tf 10.7452 0 0 10.7452 70.201 180.9988 Tm -0.009 Tc [(|LN)-24.1(\))-11( )]TJ /F6 1 Tf 2.3341 0 TD -0.0049 Tc 0.2239 Tw (= P)Tj /F5 1 Tf 1.7422 0 TD 0 Tc 0 Tw (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 118.321 180.9988 Tm (?)Tj /F5 1 Tf 10.7452 0 0 10.7452 128.761 180.9988 Tm (|)Tj /F6 1 Tf 0.1787 0 TD 0.0043 Tc [()]TJ /F5 1 Tf 2.5798 0 TD -0.0091 Tc (\) )Tj /F6 1 Tf 0.7929 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 177.8409 180.9988 Tm (@)Tj /F5 1 Tf 10.7452 0 0 10.7452 188.041 180.9988 Tm (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 190.8009 180.9988 Tm (?)Tj /F5 1 Tf 10.7452 0 0 10.7452 201.1209 180.9988 Tm 0.0132 Tc (\) )Tj /F6 1 Tf 0.8153 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 220.8009 180.9988 Tm (4)Tj /F5 1 Tf 10.7452 0 0 10.7452 231.3609 180.9988 Tm (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 233.881 180.9988 Tm (@)Tj /F5 1 Tf 10.7452 0 0 10.7452 244.321 180.9988 Tm 0.002 Tc (\) )Tj /F6 1 Tf 0.8041 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 263.8809 180.9988 Tm (A)Tj /F5 1 Tf 10.7452 0 0 10.7452 274.3209 180.9988 Tm (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 276.8409 180.9988 Tm (4)Tj /F5 1 Tf 10.7452 0 0 10.7452 287.2809 180.9988 Tm 0.0132 Tc (\) )Tj -20.2026 -1.4742 TD 0.0069 Tc [( )-122.8( )]TJ ET 1 i 70.201 167.919 140.16 -0.6 re f BT 10.7452 0 0 10.7452 210.3609 165.1588 Tm 0 Tc ( )Tj 7.4287 0 0 7.4287 70.201 154.9588 Tm (4)Tj 0.5492 -0.3877 TD ( )Tj 8.76 0 0 8.76 76.0809 152.0788 Tm -0.005 Tc 0.1797 Tw [(T)-10.4(h)-11.8(e d)-25.5(e)14.3(t)-14.7(a)0.6(il)-28.4(e)14.3(d)-11.9( d)-25.5(e)14.3(scr)-14.5(i)-1(p)-11.8(t)-14.7(ion)-11.8( of)-14.5( )-13.7(th)-25.5(e)14.3(s)-13.3(e )-27.4(m)5.9(o)1.8(d)-25.5(e)14.3(l)-14.7(s)0.4( )-13.7(ar)-14.5(e)14.3( )-13.7(in)-11.9( S)-10.6(u)-11.8(n)-11.8( )-13.7(e)14.3(t)-28.4( al. )]TJ -0.6712 -1.1644 TD -0.0058 Tc 0.112 Tw [(\()-15.3(2)-12.7(00)-12.6(2)-12.7(\))-1.6(, wh)-12.6(i)-15.5(c)-0.2(h)-12.7( al)-15.5(so)-12.6( d)-12.6(e)-0.2(s)-14.1(c)-0.2(rib)-26.3(e)-0.2(s t)-15.5(h)-12.6(e)-13.9( u)-12.6(s)-14.1(e)13.5( )-13.7(of)-15.3( )-13.7(cach)-26.3(e)-13.9( )-13.7(m)18.8(o)1(d)-26.3(e)13.5(l)-29.2( an)-12.7(d)-12.6( t)-15.5(h)-12.6(e )]TJ 0 -1.1507 TD -0.0113 Tw [(w)-9.8(a)-0.2(y)-12.7( )-13.7(th)-12.6(e )-13.7(ab)-12.7(b)-12.6(r)-15.3(e)13.5(v)1.1(i)-15.5(a)-0.2(ti)-29.2(on)-12.6(s of)-29( L)-11.2(N)-9.8( )-13.7(an)-12.6(d)-12.6( )-27.4(ON)-9.8( ar)-29(e h)-12.6(a)-0.2(n)-12.6(d)-12.7(l)-15.5(e)13.5(d)-26.3(.)11.3( )]TJ 7.4287 0 0 7.4287 70.201 121.3588 Tm 0 Tc 0 Tw (5)Tj 8.76 0 0 8.76 74.041 118.3588 Tm 0.008 Tc -0.0251 Tw [( Fo)14.9(r )-13.7(a b)-12.5(e)27.3(tte)27.3(r unde)27.3(rs)13.4(t)12(a)-0.1(ndi)12(ng)14.8(,)11.4( )-13.7(t)12(h)1.2(e co)14.8(ns)13.4(tr)12.2(a)13.6(i)-1.7(nt)12( )-13.7(i)12(s)13.4( )-13.7(a sim)18.9(p)1.2(l)12(i)12(f)-1.5(ie)27.3(d )]TJ -0.4384 -1.1507 TD -0.0051 Tc 0.0017 Tw [(v)-11.9(e)14.2(r)-14.6(s)0.3(ion)-25.6( of)-14.6( th)-11.9(at)-14.8( )13.7(u)-12(s)-27.1(e)14.2(d)-12( )13.7(i)-14.8(n)-12( ou)-11.9(r s)-13.4(y)1.7(st)-28.5(em)5.8(. )]TJ /F6 1 Tf 10.7452 0 0 10.7452 305.0409 725.9188 Tm 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD 0.0037 Tc [()]TJ /F5 1 Tf 2.8478 0 TD 0 Tc (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 347.7609 725.9188 Tm (A)Tj /F5 1 Tf 10.7452 0 0 10.7452 357.4809 725.9188 Tm 0.0022 Tc 0.0493 Tw [(\),)6.5( w)20.6(h)-0.4(ere)10.7( )11.1(<)]TJ /F6 1 Tf 4.1656 0 TD -0.0199 Tc 0 Tw (LN)Tj /F5 1 Tf 1.2173 0 TD -0.0168 Tc 0.0572 Tw [(> a)-8.3(n)-19.4(d)-8.2( <)]TJ /F6 1 Tf 3.127 0 TD 0.0012 Tc 0 Tw [(/L)10(N)]TJ /F5 1 Tf 1.4965 0 TD -0.0072 Tc 0.0364 Tw [(> a)-9.9(r)-9.2(e s)-20.2(y)23.8(mb)-9.8(o)-9.7(l)-8.4(s)-9.1( )]TJ -14.8867 -1.1503 TD 0.0024 Tc 0.172 Tw [(de)10.9(not)12.4(i)-10(n)11(g)11( the)10.9( beg)11(i)1.2(nn)11(ing)22.2( )-11.1(an)11(d the)10.9( en)11(d)11( )-11.1(of)22.7( )-11.1(a)10.9( )-11.1(L)21.5(N)-1.5(,)6.7( re-)]TJ T* 0.0124 Tc 0 Tw [(s)10.5(p)9.8(e)9.7(c)32(ti)11.2(v)21(e)9.7(ly)43.3(.)5.5( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 305.0409 675.9988 Tm -0.0068 Tc [(5.)-13.7(2.)-13.7(3)]TJ /F2 1 Tf 1.9932 0 TD 0 Tc ( )Tj /F3 1 Tf 10.7452 0 0 10.7452 332.5209 675.9988 Tm 0.0022 Tc -0.0065 Tw [(O)-12.7(r)10.7(gan)11(iza)10.8(t)0.2(ion)11( na)10.8(m)8.8(e)-0.5(s )]TJ /F5 1 Tf -2.5574 -1.664 TD 0.0018 Tc -0.0284 Tw [(O)9.1(N)-2.1(s)11.1( a)10.3(r)-0.2(e)10.3( )11.2(m)9.2(o)10.4(re)10.3( d)10.4(i)0.6(f)10.9(f)10.9(i)-10.6(c)10.3(u)-0.8(lt)11.8( )22.4(t)-10.6(o)10.4( )22.4(id)10.4(entif)-11.4(y)43.9( than)10.4( )22.4(P)10.6(N)-2.1(s)11.1( a)21.4(n)-0.8(d)10.4( L)20.9(N)-2.1(s)11.1( )]TJ 0 -1.1391 TD 0.0025 Tc 0.2724 Tw [(be)11(cau)11.1(se)11( ON)9.8(s)11.8( )-11.2(ar)11.6(e u)11.1(s)-10.5(u)11.1(a)11(l)-9.9(l)1.3(y)22.3( ne)10.9(ste)11(d)11.1( )-11.2(nam)9.9(e)-0.2(d)22.3( )-11.2(en)11.1(ti)12.5(t)-9.9(i)12.5(es)11.8(.)6.8( )]TJ 0 -1.1838 TD -0.0086 Tc [(C)-11.7(o)-11.2(ns)-10.5(i)-9.8(d)-11.2(er an)11.2( )11.1(O)-12.5(N)-12.5( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 385.4409 633.1588 Tm 0.1141 Tc 0 Tw [(BC)12.4(CDE)12.4(F)-12.3(G)12.4(H)]TJ /F5 1 Tf 10.7452 0 0 10.7452 471.601 633.1588 Tm 0.0128 Tc 0.2398 Tw [( A)20.1(i)11.6(r)21.9( C)9.7(h)21.4(in)32.6(a)21.3( )]TJ -15.5009 -1.195 TD 0.0028 Tc 0.0041 Tw [(Cor)11.9(por)11.9(at)12.8(ion)11.9(;)12.8( it)12.8( )-11.1(c)11.3(o)0.2(n)11.4(t)1.6(ain)11.4(s)12.1( an)11.4( L)10.7(N)10.1( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 442.8009 620.3188 Tm 0 Tw (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 462.2409 620.3188 Tm 0.0026 Tc -0.0069 Tw [( )11.7(C)-11.6(hi)12.6(na)11.7(.)-4.3( )]TJ -13.3455 -1.1503 TD -0.0087 Tc 0.0379 Tw [(L)10.4(i)-9.9(ke)-11.4( t)-21.1(h)-11.3(e)10.9( )-11.2(i)-9.9(d)-0.1(e)-11.4(n)-11.3(ti)-9.9(fi)-21.1(ca)-11.4(ti)-9.9(o)-11.2(n)-0.1( o)-11.2(f)0.4( LN)-12.6(s,)-15.6( an ON )-11.2(ca)-11.4(ndi)-9.9(d)-11.3(a)-0.2(t)-9.9(e)-0.2( )]TJ -1.2843 -1.1503 TD 0.0023 Tc 0.1386 Tw [(is)11.6( o)10.9(n)-0.3(l)-10.1(y)33.3( g)10.9(e)-0.4(n)10.9(e)-0.4(ra)10.8(t)-10.1(e)-0.4(d)22.1( g)22.1(i)-10.1(v)22.1(e)-0.4(n)10.9( a)10.8( )22.4(char)11.4(act)12.3(er)11.4( )11.2(stri)12.3(ng)10.9( )]TJ /F6 1 Tf 17.5223 0 TD -0.0086 Tc 0 Tw (S)Tj /F5 1 Tf 0.8153 0 TD 0.0022 Tc 0.1275 Tw [( \(l)12.2(ess)11.5( )]TJ -18.3376 -1.1391 TD 0.0021 Tc -0.0176 Tw [(than)10.7( 15)10.7( c)10.6(h)-0.5(ar)11.2(act)12.1(er)11.2(s lon)10.7(g)10.7(\))11.2(,)-4.8( if)11.2( )11.1(it end)10.7(s)11.4( in)10.7( )-11.2(a)10.6( k)10.7(e)-11.8(y)21.9(w)20.5(ord in)10.7( a)10.5( )]TJ 0 -1.195 TD 0.0027 Tc 0.0935 Tw [(1,3)11.3(5)11.3(5)0.1(-)11.8(e)0(nt)12.7(r)-21.7(y)44.8( )-11.2(ON)10( k)11.3(e)-11.2(y)22.5(w)21.1(ord list)12.7( suc)11.2(h)0.1( )11.2(as)12( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 471.2409 570.5188 Tm 0 Tw (GH)Tj /F5 1 Tf 10.7452 0 0 10.7452 490.5609 570.5188 Tm -0.0086 Tc 0.116 Tw [( )-10.6(c)-0.1(or)-21.8(po)-11.2(-)]TJ -17.2655 -1.1391 TD 0.002 Tc 0.0719 Tw [(rat)12(i)-10.4(o)10.6(n)10.6()11.1(.)-4.9( )11.2(To)10.6( e)10.5(s)0.1(tim)9.4(at)12(e)10.5( t)-10.4(h)10.6(e)21.6( )-11.1(g)21.8(e)-0.7(nera)10.5(ti)-10.4(v)10.6(e)10.5( p)10.6(r)0(o)10.6(b)-0.6(ab)10.6(ilit)-10.4(y)33( of)11.1( )11.2(a)10.4( )]TJ 0 -1.1503 TD -0.0084 Tc 0.0376 Tw [(n)-11(e)0.1(s)-21.4(t)1.6(e)-11.1(d)0.2( O)-12.3(N)-1.1(,)-15.3( )-11.2(w)10(e)-11.1( i)-20.8(n)0.2(t)-9.6(r)-10.4(o)-11(duc)-11.1(e )-11.2(wo)-11(r)-10.4(d)11.4( )-22.3(cl)-9.6(a)-11.1(s)0.9(s)-10.3( s)-10.3(e)-11.1(gme)-11.1(n)-11(t)-9.6(a)0.1(t)-9.6(i)-20.8(ons )]TJ 0 -1.1391 TD 0.0026 Tc 0 Tw [(of)11.7( )]TJ /F6 1 Tf 1.1726 0 TD (S)Tj /F5 1 Tf 0.8264 0 TD -0.0043 Tc (, )Tj /F6 1 Tf 0.5807 0 TD 0 Tc (C)Tj /F5 1 Tf 0.6701 0 TD -0.0084 Tc 0.1046 Tw [(, a)-11.1(s)0.9( hi)-20.8(dd)-11(e)-11.1(n)0.2( va)-11.1(ri)-9.6(a)-11.1(b)0.2(le)-11.1(s.)-26.4( I)11.9(n)-11( pr)-10.4(i)-9.6(n)-11(ci)-9.6(pl)-9.6(e,)-15.3( th)-11(e ON )]TJ -3.2498 -1.1503 TD 0.0022 Tc 0.0493 Tw [(clas)11.5(s m)9.6(o)-0.4(d)10.8(e)-0.5(l)12.2( rec)10.7(o)-0.4(v)10.8(e)-0.5(rs)11.5( )]TJ /F6 1 Tf 8.6886 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD 0.0026 Tc (S)Tj /F5 1 Tf 0.8376 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1899 0 TD -0.0073 Tc (ON)Tj /F5 1 Tf 1.3848 0 TD -0.0091 Tc 0.0718 Tw [(\) ove)-11.8(r al)-10.3(l )11.2(p)-11.6(o)-11.7(ss)-11(i)-10.3(b)-0.5(l)-10.3(e)-0.6( )]TJ /F6 1 Tf 7.5494 0 TD 0 Tc 0 Tw (C)Tj /F5 1 Tf 0.6701 0 TD -0.01 Tc (: )Tj /F6 1 Tf -20.2696 -1.2508 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD 0.0026 Tc (S)Tj /F5 1 Tf 0.8376 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1787 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.4071 0 TD -0.0091 Tc 0.2505 Tw [(\) =)7.7( )]TJ /TT1 1 Tf 1.8538 0 TD 0 Tc 0 Tw (I)Tj /F6 1 Tf 6.7744 0 0 6.7744 371.8809 506.3188 Tm (C)Tj 10.7452 0 0 10.7452 376.2009 507.8788 Tm (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD -0.0089 Tc [(S,)-15.8(C)]TJ /F5 1 Tf 1.7533 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1675 0 TD 0.0151 Tc (ON)Tj /F5 1 Tf 1.396 0 TD 0.002 Tc 0.2282 Tw (\) =)Tj /TT4 1 Tf 1.3848 0 TD 0 Tc 0 Tw ( )Tj /TT1 1 Tf 0.5696 0 TD (I)Tj /F6 1 Tf 6.7744 0 0 6.7744 453.8409 506.3188 Tm (C)Tj 10.7452 0 0 10.7452 458.2809 507.8788 Tm (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD (|)Tj /F6 1 Tf 0.1675 0 TD 0.0151 Tc (ON)Tj /F5 1 Tf 1.4071 0 TD 0 Tc (\))Tj /F6 1 Tf 0.3239 0 TD (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 511.6809 512.6788 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 513.9609 507.8788 Tm (|)Tj /F6 1 Tf 0.1787 0 TD 0.0031 Tc [(C,)7.4( )]TJ -19.6219 -1.195 TD -0.0073 Tc (ON)Tj /F5 1 Tf 1.3848 0 TD 0.0024 Tc -0.0179 Tw [(\).)6.7( Si)12.4(nce)10.9( )]TJ /F6 1 Tf 3.2498 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj 6.7744 0 0 6.7744 370.4409 499.9588 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 372.7209 495.0388 Tm (|)Tj /F6 1 Tf 0.1787 0 TD 0.0045 Tc (C,ON)Tj /F5 1 Tf 2.3117 0 TD -0.0074 Tc 0.0031 Tw (\) = )Tj /F6 1 Tf 1.3625 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 429.481 499.9588 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 432.0009 495.0388 Tm (|)Tj /F6 1 Tf 0.1675 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD -0.0081 Tc 0.0038 Tw [(\),)-15( w)10.3(e)-10.8( )11.2(ha)-10.8(ve)-10.8( )]TJ /F6 1 Tf 4.3108 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj 6.7744 0 0 6.7744 503.0409 499.9588 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 505.3209 495.0388 Tm (|)Tj /F6 1 Tf 0.1787 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.396 0 TD -0.0091 Tc (\) )Tj -20.2138 -1.2508 TD -0.0056 Tc (= )Tj /TT1 1 Tf 1.0163 0 TD 0 Tc (I)Tj /F6 1 Tf 6.7744 0 0 6.7744 326.7609 480.1588 Tm (C)Tj 10.7452 0 0 10.7452 331.2009 481.5988 Tm (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD (|)Tj /F6 1 Tf 0.1675 0 TD 0.0151 Tc (ON)Tj /F5 1 Tf 1.4071 0 TD -0.0091 Tc (\) )Tj /F6 1 Tf 0.7817 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.335 0 TD (S)Tj 6.7744 0 0 6.7744 389.4009 486.5188 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 391.9209 481.5988 Tm (|)Tj /F6 1 Tf 0.1675 0 TD (C)Tj /F5 1 Tf 0.6812 0 TD 0.0022 Tc 0.2057 Tw [(\))11.3(.)6.5( )-11.1(W)8.1(e)-0.5( then)10.8( )11.2(assum)9.6(e)10.7( tha)10.7(t)12.2( )-11.1(t)-10.2(h)22(e)10.7( )]TJ -8.9343 -1.1838 TD 0.0021 Tc 0.2951 Tw [(sum)9.5( )11.1(i)-10.3(s)11.4( )11.1(app)10.7(r)0.1(ox)10.7(im)9.5(ated)10.7( by)33.1( )-11.2(a)10.6( sing)21.9(l)-10.3(e)10.6( pa)10.6(ir)11.2( of)11.2( te)10.6(rm)9.5(s)11.4( )]TJ /F6 1 Tf 0 -1.1503 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (C)Tj 6.7744 0 0 6.7744 322.4409 461.4388 Tm (*)Tj /F5 1 Tf 10.7452 0 0 10.7452 325.8009 456.5188 Tm (|)Tj /F6 1 Tf 0.1787 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.396 0 TD 0 Tc (\))Tj /F6 1 Tf 0.3239 0 TD (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD (S)Tj 6.7744 0 0 6.7744 361.8009 461.4388 Tm ()Tj /F5 1 Tf 10.7452 0 0 10.7452 364.0809 456.5188 Tm (|)Tj /F6 1 Tf 0.1787 0 TD (C)Tj 6.7744 0 0 6.7744 373.2009 461.4388 Tm (*)Tj /F5 1 Tf 10.7452 0 0 10.7452 376.5609 456.5188 Tm 0.0132 Tc 0.1835 Tw [(\),)17.5( w)31.6(h)10.6(e)10.5(r)22.3(e)21.7( )]TJ /F6 1 Tf 3.8864 0 TD 0 Tc 0 Tw (C)Tj 6.7744 0 0 6.7744 425.5209 461.4388 Tm (*)Tj /F5 1 Tf 10.7452 0 0 10.7452 428.7609 456.5188 Tm 0.0022 Tc 0.1833 Tw [( i)-10.2(s)11.5( th)10.8(e)10.7( )-11.2(m)9.6(o)-0.3(s)11.5(t)12.2( prob)22(abl)12.2(e)10.6( )]TJ -11.514 -1.1391 TD 0.0024 Tc 0.038 Tw [(w)20.8(o)-0.2(rd cla)10.9(s)0.5(s)11.7( )-11.1(seg)22.2(m)9.8(ent)12.4(a)-0.3(tion)11( di)12.4(scov)22.2(er)-10.8(e)10.9(d)11( )-11.1(by)33.3( E)-12(q)11(.)6.7( 2)11(.)-4.5( )11.2(Tha)10.9(t)12.4( )]TJ T* -0.0087 Tc -0.0179 Tw [(i)-9.9(s)0.6(,)-15.6( w)9.7(e)-11.4( )-11.1(al)-9.9(s)-10.6(o)-0.1( us)-10.6(e o)-11.3(u)-0.1(r)-10.7( s)-21.7(y)33.4(s)-10.6(t)-21.1(e)-11.4(m)-1.3( t)-9.9(o)-0.1( )-11.1(fi)-9.9(n)-11.2(d)-0.1( )]TJ /F6 1 Tf 13.2339 0 TD 0 Tc 0 Tw (C)Tj /F5 1 Tf 6.7744 0 0 6.7744 454.5609 436.9588 Tm (*)Tj 10.7452 0 0 10.7452 457.8009 432.0388 Tm 0.0021 Tc -0.0287 Tw [(,)6.4( )-11.1(bu)21.9(t th)10.7(e so)10.7(u)10.7(r)0.1(ce-)22.4( )]TJ -14.2166 -1.1503 TD 0.003 Tc 0.0039 Tw [(ch)11.6(anne)11.5(l)13( )-11.1(m)10.4(o)11.6(de)11.5(ls )11.2(are)11.5( )11.2(es)12.3(t)-9.4(i)1.8(m)10.4(a)11.5(t)13(e)0.3(d)11.6( on)11.6( th)11.6(e)11.5( O)10.3(N)10.3( )-11.1(l)13(i)1.8(s)12.3(t)1.8(. )]TJ 1.2843 -1.1503 TD -0.0087 Tc 0.0491 Tw [(C)-11.8(o)-11.3(ns)-10.6(i)-9.9(d)-11.3(er t)-9.9(h)-11.2(e )-11.1(ea)-11.4(rl)-21.1(ie)-11.4(r )-11.1(e)-11.4(x)-0.1(a)-11.4(m)-1.3(pl)-9.9(e.)-15.6( A)-12.6(s)-10.6(su)-11.2(mi)-9.9(n)-11.3(g)-0.1( t)-9.9(h)-11.3(at)-9.9( )]TJ /F6 1 Tf 18.2706 0 TD 0 Tc 0 Tw (C)Tj /F5 1 Tf 6.7744 0 0 6.7744 522.3609 412.2388 Tm (*)Tj 10.7452 0 0 10.7452 525.7209 407.3188 Tm ( )Tj -20.5376 -1.1838 TD -0.0056 Tc -0.0099 Tw [(= L)13.5(N)-9.5(/)]TJ /TT1 1 Tf 9.6942 0 0 9.6942 330.7209 394.5988 Tm 0.0027 Tc 0 Tw (CD)Tj /F5 1 Tf 10.7452 0 0 10.7452 350.0409 394.5988 Tm 0 Tc (/)Tj /TT1 1 Tf 9.6942 0 0 9.6942 353.1609 394.5988 Tm 0.0027 Tc (EF)Tj /F5 1 Tf 10.7452 0 0 10.7452 372.4809 394.5988 Tm 0 Tc (/)Tj /TT1 1 Tf 9.6942 0 0 9.6942 375.601 394.5988 Tm -0.0097 Tc (GH)Tj /F5 1 Tf 10.7452 0 0 10.7452 394.9209 394.5988 Tm 0.0041 Tc -0.0307 Tw [(, w)22.5(h)1.5(er)13.2(e )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 428.6409 394.5988 Tm -0.0097 Tc 0 Tw (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 447.8409 394.5988 Tm 0.0022 Tc -0.0288 Tw [( is)11.5( )11.2(t)-10.2(a)-0.5(g)22(g)10.8(ed as)11.5( a)10.7( L)10.1(N)9.5(,)6.5( )]TJ -13.2897 -1.1503 TD 0.0021 Tc -0.0511 Tw [(the)10.6( prob)10.7(ab)10.7(ili)12.1(t)-21.4(y)33.1( )]TJ /F6 1 Tf 5.9971 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.335 0 TD -0.0086 Tc (S)Tj /F5 1 Tf 0.8376 0 TD 0 Tc (|)Tj /F6 1 Tf 0.1675 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.4072 0 TD -0.0087 Tc -0.0291 Tw [(\) woul)-21.1(d)11.1( )-11.2(be es)-10.6(ti)-21.1(ma)-11.4(te)-11.4(d us)-10.6(i)-9.9(n)-11.3(g)11.1( a )]TJ -9.3586 -1.1838 TD 0.0024 Tc 0.1496 Tw [(w)20.8(o)-0.2(rd c)10.9(l)1.2(ass)11.7( )11.1(big)11(r)0.4(am)21( m)9.8(ode)10.9(l)12.4( )11.1(as:)12.4( )]TJ /F6 1 Tf 12.3516 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 447.9609 369.5188 Tm 0.0027 Tc [(BCC)12.4(DEF)-12.3(GH)]TJ /F5 1 Tf 10.7452 0 0 10.7452 305.0409 355.9588 Tm 0 Tc (|)Tj /F6 1 Tf 0.1787 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.4071 0 TD -0.0091 Tc (\) )Tj /TT1 1 Tf 0.7482 0 TD 0 Tc (J)Tj /TT4 1 Tf 1.0051 0 TD ( )Tj /F6 1 Tf 0.5026 0 TD (P)Tj /F5 1 Tf 0.6254 0 TD 0.002 Tc [(\(L)9.9(N)9.3(/)]TJ /TT1 1 Tf 9.6942 0 0 9.6942 374.041 355.9588 Tm 0.0274 Tc (CD)Tj /F5 1 Tf 10.7452 0 0 10.7452 393.8409 355.9588 Tm 0 Tc (/)Tj /TT1 1 Tf 9.6942 0 0 9.6942 397.2009 355.9588 Tm 0.015 Tc (EF)Tj /F5 1 Tf 10.7452 0 0 10.7452 416.8809 355.9588 Tm 0 Tc (/)Tj /TT1 1 Tf 9.6942 0 0 9.6942 420.0009 355.9588 Tm 0.0274 Tc (GH)Tj /F5 1 Tf 10.7452 0 0 10.7452 440.041 355.9588 Tm 0 Tc (|)Tj /F6 1 Tf 0.1787 0 TD 0.0039 Tc (ON)Tj /F5 1 Tf 1.396 0 TD -0.0091 Tc (\) )Tj /F6 1 Tf 0.7482 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 475.4409 355.9588 Tm 0.0274 Tc (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 495.361 355.9588 Tm -0.0102 Tc 0.1957 Tw [(|L)8.9(N)-25.3(\))-1.1( =)6.6( )178.6( )]TJ /F6 1 Tf -17.7122 -1.2285 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6142 0 TD 0.003 Tc [(\(L)10.9(N|)]TJ /F6 1 Tf 1.8427 0 TD 0.0047 Tc [()]TJ /F5 1 Tf 2.7473 0 TD 0 Tc (\))Tj /F6 1 Tf 0.3239 0 TD (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 374.8809 342.7589 Tm 0.015 Tc (CD)Tj /F5 1 Tf 10.7452 0 0 10.7452 394.5609 342.7589 Tm -0.0101 Tc [(|L)9(N)-25.2(\))]TJ /F6 1 Tf 1.8539 0 TD 0 Tc (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 424.6809 342.7589 Tm 0.015 Tc (EF)Tj /F5 1 Tf 10.7452 0 0 10.7452 444.601 342.7589 Tm 0 Tc (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 446.6409 342.7589 Tm 0.0274 Tc (CD)Tj /F5 1 Tf 10.7452 0 0 10.7452 466.4409 342.7589 Tm 0 Tc (\))Tj /F6 1 Tf 0.335 0 TD (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 480.481 342.7589 Tm 0.0027 Tc (GH)Tj /F5 1 Tf 10.7452 0 0 10.7452 500.1609 342.7589 Tm 0 Tc (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 502.3209 342.7589 Tm 0.015 Tc (EF)Tj /F5 1 Tf 10.7452 0 0 10.7452 522.0009 342.7589 Tm 0.0132 Tc (\) )Tj /F6 1 Tf -20.1914 -1.195 TD 0 Tc (P)Tj /F5 1 Tf 0.6142 0 TD (\()Tj /F6 1 Tf 0.3239 0 TD 0.0062 Tc [()]TJ /F5 1 Tf 3.0153 0 TD 0 Tc (|)Tj /TT1 1 Tf 9.6942 0 0 9.6942 349.9209 329.9188 Tm 0.0398 Tc (GH)Tj /F5 1 Tf 10.7452 0 0 10.7452 370.2009 329.9188 Tm 0 Tc (\))Tj /F6 1 Tf 0.335 0 TD (P)Tj /F5 1 Tf 0.6254 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 384.601 329.9188 Tm 0.0398 Tc (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 405.0009 329.9188 Tm -0.0199 Tc 0.2278 Tw [(|L)-12(N)-23.8(\))-10.8(,)-26.8( wh)-22.4(e)-22.6(r)-21.9(e)-11.4( )]TJ /F6 1 Tf 5.4164 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6031 0 TD (\()Tj /TT1 1 Tf 9.6942 0 0 9.6942 473.7609 329.9188 Tm 0.0522 Tc (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 494.1609 329.9188 Tm -0.0213 Tc 0.2292 Tw [(|L)-13.4(N)-25.2(\))-12.2( i)-11.3(s)-12( )]TJ -17.6005 -1.195 TD 0.0019 Tc 0.005 Tw [(the)10.4( c)10.4(l)0.7(as)11.2(s)11.2( )-11.1(m)9.3(o)-0.6(d)10.5(e)-0.8(l p)10.5(r)-0.1(oba)21.5(b)-0.7(ili)11.9(t)-21.6(y)44( )-11.1(of)11( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 435.1209 317.0788 Tm 0.0027 Tc 0 Tw (BC)Tj /F5 1 Tf 10.7452 0 0 10.7452 454.5609 317.0788 Tm -0.0089 Tc 0.0158 Tw [( gi)-10.1(ve)-11.6(n)-11.5( th)-11.5(a)-11.6(t)1.1( i)-10.1(t)1.1( i)-10.1(s)0.4( a )]TJ -13.9151 -1.1503 TD -0.0191 Tc 0.2046 Tw [(LN)-34.2(,)-14.8( <)]TJ /F6 1 Tf 2.5574 0 TD 0.0039 Tc 0 Tw (ON)Tj /F5 1 Tf 1.396 0 TD -0.0086 Tc 0.183 Tw [(>)-14.2( a)-11.3(nd )-11.1(<)]TJ /F6 1 Tf 3.4174 0 TD 0.0012 Tc 0 Tw [(/O)8.5(N)]TJ /F5 1 Tf 1.664 0 TD 0.0021 Tc 0.1834 Tw [(>)7.7( )11.1(ar)11.2(e s)-10.9(y)33(m)9.5(b)-0.5(ols de)10.6(n)10.7(o)-0.5(ting)21.9( th)10.7(e)10.6( )]TJ -9.0348 -1.1391 TD -0.0083 Tc 0.004 Tw [(b)-10.9(e)0.2(gi)-20.7(nn)-10.9(i)-9.5(n)-10.9(g a)-11(n)-10.9(d t)-20.7(h)0.3(e )-22.3(end )-11.2(o)-10.9(f)12( )-22.3(a ON)-12.2(, )-11.2(r)-10.3(e)-11(s)-10.2(p)0.3(ec)-11(ti)-20.7(ve)-11(l)-20.7(y)22.7(.)-15.2( )-11.2( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 305.0409 267.1588 Tm -0.0068 Tc 0 Tw [(5.)-13.7(2.)-13.7(4)]TJ /F2 1 Tf 1.9932 0 TD 0 Tc ( )Tj /F3 1 Tf 10.7452 0 0 10.7452 332.5209 267.1588 Tm 0.0021 Tc -0.0064 Tw [(T)-12.1(r)-0.6(a)10.7(n)10.9(slite)10.6(r)-0.6(at)11.2(ions)11.4( of)11.2( f)-11.1(o)10.7(r)10.6(e)-0.6(ig)10.7(n )-11.2(nam)8.7(e)10.6(s )]TJ /F5 1 Tf -2.5574 -1.6528 TD -0.0089 Tc -0.0289 Tw [(A)-12.8(s)0.4( )-11.2(d)10.9(e)-11.6(s)-10.8(c)-0.4(r)-10.9(i)-21.3(b)10.9(e)-11.6(d )-11.2(i)-10.1(n)-0.3( Sp)-11.5(r)-10.9(o)-11.5(at et)-10.1( al.)-15.8( \(1)-11.5(9)-11.5(9)-11.4(6\))-10.9(: FN)-12.8(s )-11.2(ar)-10.9(e us)-10.8(u)-11.4(a)-0.4(l)-10.1(l)-32.4(y)22( )]TJ 0 -1.1503 TD 0.0022 Tc -0.0065 Tw [(tran)10.8(sl)12.2(i)-10.2(t)12.2(era)10.7(t)1(ed)10.8( )22.3(us)11.5(i)-10.2(n)10.8(g)22( C)10.3(h)-0.4(in)10.8(ese)10.7( )22.3(cha)10.7(r)0.2(ac)10.7(te)10.7(r)11.3( s)11.5(t)1(r)11.3(i)-10.2(n)10.8(g)10.8(s)11.5( w)20.6(h)-0.4(o)10.8(s)0.3(e)10.7( )]TJ 0 -1.1391 TD -0.0086 Tc 0.3058 Tw 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w)20.5(e)-0.6( use)10.6( )11.1(a g)10.7(r)0.1(eed)-11.6(y)33.1( w)20.5(o)-0.5(rd seg)10.7(m)9.5(en-)]TJ T* 0.0124 Tc 0 Tw [(to)21(r)]TJ 6.3071 0 0 6.3071 82.8009 427.7188 Tm 0 Tc (6)Tj 10.7452 0 0 10.7452 86.881 424.7188 Tm 0.0023 Tc 0.2167 Tw [( )212.1(t)12.3(o)-0.3( ann)10.9(o)10.9(t)1.1(ate)10.8( t)-10.1(h)10.9(e)10.8( corp)10.9(us)11.6(,)6.6( )-11.2(and)10.9( o)10.9(b)-0.3(ta)10.8(in)10.9( )-11.2(an)10.9( ini)12.3(tial)23.4( )]TJ -1.5523 -1.1391 TD 0.0022 Tc -0.0177 Tw [(contex)10.8(t)12.2( m)9.6(o)10.8(d)10.8(e)-0.5(l )22.3(bas)11.5(e)-0.5(d)22( on)22( )11.1(the)10.7( )33.5(i)-10.2(n)10.8(iti)12.2(al )22.3(anno)22(t)-10.2(a)-0.5(t)12.2(e)-0.5(d)10.8( )11.1(c)10.7(o)-0.4(rpu)10.8(s)0.3(;)12.2( )]TJ 0 -1.1503 TD 0.0023 Tc 0.1832 Tw [(\()-10.9(2)10.9(\))11.4( )-11.2(w)9.6(e)-0.4( re-)11.4(a)-0.4(n)10.9(not)12.3(ate)10.8( t)-10.1(h)-0.3(e)21.9( )-11.2(c)10.8(o)-0.3(r)11.4(pus us)11.6(ing)22.1( )-11.2(t)-10.1(h)10.9(e)10.8( obt)12.3(ain)10.9(e)-0.4(d)10.9( )]TJ 0 -1.1391 TD -0.0178 Tw [(m)9.7(odels)11.6(; and)10.9( )11.1(\(3\))11.4( re-)11.4(t)1.1(r)11.4(a)-0.4(i)-10.1(n)22.1( the)10.8( )11.1(contex)10.9(t)12.3( mo)10.9(de)10.8(l)12.3( )-11.2(us)11.6(ing)10.9( t)12.3(h)-0.3(e)10.8( )]TJ T* 0.0024 Tc 0.0045 Tw [(r)-10.8(e)10.9(-an)11(n)-0.2(o)11(t)1.2(at)12.4(ed )11.2(cor)11.5(pus)11.7(.)6.7( )-11.1(S)11.2(t)1.2(ep)11(s)11.7( 2 and)22.2( )-11.1(3)11( a)10.9(r)0.4(e)10.9( iter)11.5(a)-0.3(te)10.9(d u)11(n)-0.2(t)12.4(i)-10(l)12.4( )]TJ 0 -1.1503 TD -0.0085 Tc 0.0265 Tw [(t)-20.9(h)0.1(e per)-21.7(f)0.6(o)-11.1(r)-10.5(ma)-11.2(nce o)-11.1(f)11.8( )11.1(t)-9.7(h)0.1(e s)-21.5(y)33.6(s)-10.4(t)-20.9(e)-11.2(m)-1.1( )11.1(co)-11.1(n)-11.1(v)11.3(e)-11.2(r)-10.5(ge)-11.2(s.)-26.5( )]TJ 1.2843 -1.1503 TD 0.0022 Tc -0.0065 Tw [(I)22.5(n)-0.4( )-22.3(the)10.7( abo)10.8(v)10.8(e)10.7( )-22.3(a)10.7(p)10.8(pro)10.8(ach)10.8(,)6.5( t)-10.2(h)10.8(e)10.7( qu)10.8(alit)-10.2(y)33.2( )-11.2(of)22.5( )-22.3(th)10.8(e)10.7( cont)12.2(ex)10.8(t )]TJ -1.2843 -1.1391 TD 0.0023 Tc [(m)9.7(odel)12.3( )-11.2(d)22.1(e)-0.4(pend)10.9(s)11.6( )11.2(to)10.9( a)10.8( l)12.3(a)-0.4(rg)10.9(e)10.8( de)10.8(g)10.9(r)0.3(ee)10.8( upon)22.1( th)10.9(e)10.8( qu)10.9(al)12.3(it)-21.2(y)33.3( of)22.6( )]TJ 0 -1.1503 TD 0.0022 Tc 0.094 Tw [(t)-10.2(h)10.8(e)10.7( )-11.2(ini)12.2(tia)10.7(l ann)10.8(o)10.8(t)-10.2(a)21.8(t)-10.2(ed)22( )-11.2(co)10.8(rp)10.8(us)11.5(,)6.5( )-22.3(w)20.6(h)-0.4(ich)10.8( is)11.5( how)20.6(ev)10.8(er )-11.2(no)10.8(t)12.2( )]TJ 0 -1.1391 TD 0.0019 Tc 0.2618 Tw [(satisf)11(i)0.7(ed)10.5( du)10.5(e)10.4( to)10.5( tw)9.2(o)21.7( )-11.2(prob)10.5(lem)9.3(s)11.2(.)6.2( )-11.2(F)10.7(i)0.7(r)11(s)0(t,)6.2( the)10.4( )-11.2(g)21.7(r)-0.1(e)10.4(e)-0.8(d)-11.8(y)32.9( )]TJ T* -0.0086 Tc 0.1383 Tw [(s)-10.5(e)-11.3(gme)-11.3(n)-11.2(t)-9.8(o)-11.2(r ca)-11.3(n)-11.2(n)-11.2(o)11.2(t)-21( )11.2(d)-11.2(eal)-9.8( w)9.8(i)-9.8(t)-21(h)0( t)-9.8(h)-11.2(e se)-11.3(g)11.2(m)-12.3(en)-11.2(t)-21(a)-0.1(t)-9.8(i)-9.8(o)-11.2(n a)-11.3(m)-1.2(-)]TJ 0 -1.1615 TD 0.002 Tc 0.1054 Tw [(big)10.6(u)-0.6(ities)11.3(,)6.3( and)10.6( ev)10.6(en)21.8( )-11.1(a)10.5(f)0(te)10.5(r )11.2(i)-10.4(t)12(era)10.5(tion)10.6(s)11.3(,)-16( )11.2(the)10.5(s)0.1(e)10.5( am)9.4(big)10.6(u)10.6(i)-10.4(-)]TJ 0 -1.1391 TD 0.0023 Tc 0.1497 Tw [(t)-10.1(i)1.1(e)10.8(s)11.6( ca)10.8(n)10.9( o)10.9(n)10.9(l)-21.2(y)44.4( be)10.8( pa)10.8(rt)12.3(i)-10.1(a)10.8(ll)-10.1(y)33.3( r)11.4(e)-0.4(solv)10.9(ed)10.9(.)6.6( S)11.1(eco)10.9(nd)10.9(,)6.6( m)20.9(a)-0.4(n)-11.4(y)22.1( )]TJ T* -0.0087 Tc 0.2724 Tw [(f)-10.7(a)-0.2(c)-11.4(t)-21.1(oi)-21.1(ds )11.1(a)-11.4(n)-11.3(d )11.1(na)-11.4(me)-11.4(d e)-11.4(n)-0.1(t)-9.9(i)1.3(t)-9.9(i)1.3(e)-11.4(s)0.6( ca)-11.4(nn)-11.3(o)-11.3(t)1.3( be )11.1(i)-21.1(d)11.1(e)-11.4(n)-11.3(ti)-21.1(fi)-9.9(e)-11.4(d)-0.1( )]TJ 0 -1.1503 TD 0.0043 Tw [(u)-11.2(s)-10.5(i)-9.8(n)-11.2(g)11.2( t)-21(h)0(e)11( )-11.2(gr)-10.6(e)-11.3(e)-11.3(d)-11.2(y)22.4( )-11.2(w)9.8(o)-11.2(r)-10.6(d)-11.2( )11.2(s)-10.5(e)-11.3(gme)-11.3(n)-11.2(t)-9.8(o)-11.2(r whi)-21(c)-11.3(h)11.2( is )-11.2(bas)-10.5(e)-11.3(d on )]TJ 0 -1.1391 TD 0.0266 Tw [(t)-21(h)0(e di)-9.8(ct)-9.8(i)-9.8(o)-11.2(na)-11.3(r)-21.8(y)22.4(.)-15.5( )]TJ 1.2843 -1.1503 TD 0.0025 Tc 0.0379 Tw [(T)-11.9(o)22.3( )-11.1(so)11.1(lv)11.1(e t)12.5(h)-0.1(e f)11.6(i)1.3(rs)11.8(t p)11.1(r)-10.7(o)11.1(b)11.1(l)1.3(em)21.1(, )11.2(w)20.9(e)-0.2( )-11.1(u)11.1(s)0.6(e tw)20.9(o m)9.9(e)-0.2(t)-9.9(h)11.1(od)11.1(s )]TJ -1.2843 -1.1503 TD 0.0018 Tc 0.1949 Tw [(t)-10.6(o)21.6( r)-11.4(e)21.4(s)-11.2(o)10.4(l)-10.6(v)21.6(e)10.3( s)11.1(e)-0.9(g)10.4(m)9.2(entat)11.8(i)-10.6(o)10.4(n)10.4( a)10.3(m)9.2(big)10.4(u)-0.8(ities)11.1( i)11.8(n)10.4( th)10.4(e )11.2(in)10.4(it)11.8(i)-10.6(a)10.3(l)11.8( )]TJ 0 -1.1391 TD -0.0082 Tc 0.2943 Tw [(s)-10.1(e)-10.9(gme)-10.9(n)-10.8(t)-9.4(e)-10.9(d tr)-10.2(ai)-9.4(n)-10.8(i)-9.4(n)-10.8(g)0.4( )11.2(da)-10.9(t)-9.4(a)0.3(. )11.2(We c)-10.9(l)1.8(a)-10.9(s)-10.1(si)-20.6(f)-10.2(y)22.8( wor)-21.4(d)0.4( se)-10.9(g-)]TJ T* 0.0021 Tc 0.3063 Tw [(m)9.5(e)-0.6(ntation)10.7( am)9.5(big)10.7(u)-0.5(it)12.1(i)-10.3(e)-0.6(s)11.4( i)-10.3(n)10.7(to tw)9.4(o )-11.2(cl)12.1(ass)11.4(e)-0.6(s: )-11.2(ov)10.7(er)11.2(lap)21.9( )]TJ 0 -1.1503 TD 0.0023 Tc 0.0269 Tw [(am)9.7(big)10.9(u)-0.3(it)-21.2(y)44.4( )-22.3(\()11.4(O)9.6(A\),)6.6( and)10.9( com)9.7(b)10.9(inat)12.3(ion)10.9( am)9.7(big)10.9(u)-0.3(i)12.3(t)-10.1(y)33.3( )-22.3(\()11.4(C)-0.8(A)9.6(\))0.3(.)6.6( )]TJ T* -0.0087 Tc 0.1161 Tw [(C)-22.9(ons)-10.6(i)-21.1(d)-0.1(er)-10.7( a cha)-11.4(r)-10.7(ac)-11.4(t)-9.9(e)-11.4(r st)-9.9(ri)-21.1(n)-11.3(g)11.1( )11.2(A)-12.6(B)-11.8(C,)-15.6( )11.2(i)-9.9(f)0.4( i)-9.9(t)1.3( )11.2(c)-11.4(a)-11.4(n)-0.1( b)-11.3(e)-0.2( )11.2(s)-10.6(e)-11.4(g-)]TJ 0 -1.4183 TD 0.0069 Tc 0 Tw [( )-122.8( )]TJ ET 1 i 70.201 153.879 140.16 -0.6 re f BT 10.7452 0 0 10.7452 210.3609 151.1188 Tm 0 Tc ( )Tj 6.7744 0 0 6.7744 70.201 141.3988 Tm (6)Tj 9.6942 0 0 9.6942 73.681 138.5188 Tm ( )Tj 8.76 0 0 8.76 76.0809 138.5188 Tm -0.0065 Tc -0.0106 Tw [(T)-11.9(h)-13.3(e)12.8( )-13.7(gr)-29.7(ee)12.8(d)-13.4(y)-13.3( )-13.7(w)-10.5(o)0.4(rd)-13.3( )-13.7(s)-14.8(e)-0.9(gm)-23(e)12.8(n)-13.3(tor)-29.7( i)-16.2(s)-14.8( b)-13.3(a)-14.6(s)-14.8(e)12.8(d)-27( on)-13.3( )-27.4(a)-14.6( f)-16(o)0.3(rw)-10.5(ard)-27( )-13.7(max)-13.4(i)-16.2(mu)-27(m )]TJ -0.6712 -1.1644 TD 0.0077 Tc -0.0248 Tw [(ma)13.3(t)11.7(c)13.3(hing)14.5( \(FM)6.3(M)6.3(\))11.9( )-13.7(a)13.3(l)-2(g)14.6(o)14.5(ri)11.7(thm)32.3(:)-15.7( )-13.7(I)25.6(t)-15.7( pro)14.5(c)-0.4(e)27(s)13.1(se)13.3(s)-14.3( thr)11.9(o)14.5(u)-12.8(g)28.2(h the)13.3( )-13.7(se)27(nte)27(n)0.9(c)-14.1(e)13.3( )]TJ 0 -1.1507 TD 0.0089 Tc -0.0123 Tw [(fr)13.1(om)19.8( le)14.5(f)13.1(t)12.9( to)15.7( r)13.1(i)-14.5(g)29.4(h)2.1(t,)12.3( t)12.9(a)0.8(k)15.7(i)12.9(n)-11.6(g)15.7( )13.7(th)-11.6(e)28.2( lo)15.8(n)-11.6(g)15.7(e)14.5(s)14.3(t m)19.8(a)14.5(tc)14.5(h w)18.6(i)-0.8(t)12.9(h)2.1( t)12.9(h)-11.6(e)28.2( le)28.2(xico)15.7(n )]TJ 0 -1.137 TD -0.0193 Tc 0.0159 Tw [(en)-26.1(t)-29(r)-15.1(y)-26.1( a)-13.7(t)-29( )-13.7(ea)-27.4(c)-13.7(h)-26.2( p)-26.2(o)-12.4(i)-15.3(n)-26.2(t)-29(.)]TJ 9.6942 0 0 9.6942 137.2809 108.2788 Tm 0 Tc 0 Tw ( )Tj 10.7452 0 0 10.7452 305.0409 726.3988 Tm 0.0023 Tc 0.1944 Tw [(m)9.7(e)-0.4(nted)10.9( )11.2(i)-10.1(n)-0.3(t)12.3(o)10.9( )-11.2(tw)20.7(o )-11.2(w)20.7(o)-0.3(rds)11.6( ei)12.3(ther)11.4( as)11.6( A)9.6(B)-0.8(/C)10.4( or)11.4( A)9.6(/)1.1(BC)21.6( )]TJ 0 -1.1503 TD 0.1497 Tw [(de)10.8(pend)10.9(ing)10.9( o)10.9(n)10.9( d)10.9(i)1.1(ff)11.4(eren)10.9(t )11.1(co)10.9(n)10.9(t)-10.1(e)10.8(x)10.9(t,)6.6( A)9.6(B)-0.8(C)10.4( i)12.3(s)11.6( ca)10.8(l)-10.1(l)12.3(ed)10.9( an)22.1( )]TJ T* 0.0024 Tc 0.3618 Tw [(ov)22.2(erl)-10(a)-0.3(p)22.2( am)9.8(b)11(i)1.2(g)11(u)-0.2(it)-10(y)33.4( st)12.4(ring)22.2( )11.1(\(O)9.7(AS)11.2(\))11.5(.)6.7( I)22.7(f)11.5( a )11.1(c)10.9(h)-0.2(ar)11.5(act)12.4(er)11.5( )]TJ 0 -1.1391 TD -0.0084 Tc 0.0488 Tw [(s)-10.3(t)-9.6(ri)-20.8(ng)11.4( )-11.1(A)-12.3(B)-0.3( c)-11.1(a)0.1(n )-11.1(b)-11(e)0.1( se)-11.1(gme)-11.1(n)-10.9(t)-9.6(e)0.1(d )-11.1(e)-11.1(i)1.6(t)-20.8(h)0.2(er)-10.4( i)-9.6(n)0.2(t)-9.6(o)0.2( t)-20.8(w)10(o)-11( )-11.1(w)10(o)-11(r)-10.4(d)-11(s, )]TJ T* 0.0025 Tc -0.0291 Tw [(A/)12.5(B,)6.8( o)11.1(r)0.5( a)11(s)11.8( on)11.1(e)11( w)9.8(o)11.1(r)-10.7(d)11.1( de)11(pe)11(nd)11.1(ing)11.1( on)11.1( )11.2(dif)11.6(f)0.5(eren)22.3(t co)11.1(ntex)11.1(t)12.5(.)6.8( )]TJ 0 -1.1503 TD 0.0022 Tc -0.0288 Tw [(A)9.5(B)10.3( )-11.1(is)11.5( ca)10.7(lled)10.8( )11.2(a co)10.8(m)9.6(b)-0.4(i)-10.2(n)22(ation)22( am)9.6(big)10.8(u)-0.4(it)-10.2(y)33.2( s)-10.8(t)1(r)11.3(i)1(ng)10.8( )11.2(\()-11(C)10.3(AS)11(\))11.3(.)6.5( )]TJ T* -0.0177 Tw [(To)10.8( r)-11(e)-0.5(s)11.5(o)10.8(l)-10.2(v)10.8(e)21.8( )-22.4(O)9.5(A)9.5(,)-4.7( )-11.2(w)20.6(e)10.7( )-22.4(id)10.8(en)10.8(tify)33.2( )-11.2(al)-10.2(l)12.2( OASs)11.5( in)10.8( )-11.2(the)10.7( tr)11.3(ai)-10.2(n)22(i)-10.2(ng)22( )]TJ 0 -1.1391 TD -0.0082 Tc 0.0597 Tw [(d)-10.8(a)0.3(t)-20.6(a)0.3( a)-10.9(n)-10.8(d)11.6( )-11.2(r)-10.2(e)0.3(p)-10.8(l)-9.4(ac)-10.9(e t)-9.4(h)-10.7(e)-10.9(m)10.4( )-11.2(wi)-9.4(t)-9.4(h)0.4( a )-11.2(si)-20.6(ngl)-20.6(e t)-9.4(o)-10.8(ke)-10.9(n)11.6( )-22.4(<)8.6(O)-0.9(A)-23.3(S)0.6(>.)7.3( )]TJ 0 -1.1503 TD 0.2385 Tw [(B)-22.5(y)22.7( d)-10.9(o)0.3(i)-20.7(ng so, w)10.1(e)-11( a)-11(c)0.2(t)-9.5(u)-10.9(al)-9.5(l)-31.8(y)22.6( re)-11(mo)-10.9(ve)-11( th)-10.9(e por)-10.3(t)-9.5(i)-9.5(o)-10.9(n )11.2(o)-10.9(f)12( )]TJ 0 -1.1391 TD 0.0023 Tc -0.0289 Tw [(tra)10.8(i)1.1(nin)10.9(g)10.9( )-11.1(d)10.9(a)10.8(t)-10.1(a)10.8( th)10.9(at)12.3( )-11.1(a)10.8(r)0.3(e)10.8( lik)10.9(el)-10.1(y)33.3( to )-11.1(co)22.1(nta)10.8(i)-10.1(n)10.9( )11.2(OA)9.6( er)11.4(ror)11.4(s)11.6(.)-15.7( )11.2(To)22.1( )]TJ T* 0.0025 Tc 0.1384 Tw [(reso)11.1(lv)11.1(e)11( CA)9.8(, )-11.1(w)20.9(e)11( se)11(le)11(ct)12.5( 70)11.1( )11.2(hig)11.1(h)0(-)11.6(f)11.6(r)0.5(equen)11.1(t)1.3( tw)20.9(o-)11.6(char-)]TJ 0 -1.195 TD 0.0035 Tc 0.0369 Tw [(acte)12(r)12.6( C)-10.7(A)-0.4(S)12.3( \(e)12(.g)12.1(.)7.8( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 375.3609 590.5588 Tm 0.0027 Tc 0 Tw (KL)Tj /F5 1 Tf 10.7452 0 0 10.7452 394.6809 590.5588 Tm 0.002 Tc 0.0495 Tw [( t)12(ale)10.5(n)10.6(t an)10.6(d)10.6( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 450.7209 590.5588 Tm 0 Tc 0 Tw (K)Tj /F5 1 Tf 0.9779 0 TD (/)Tj /TT1 1 Tf 0.2971 0 TD (L)Tj /F5 1 Tf 10.7452 0 0 10.7452 472.6809 590.5588 Tm 0.0021 Tc 0.0494 Tw [( ju)10.7(s)0.2(t)12.1( )-11.2(ab)21.9(l)-10.3(e)10.6(\))11.2(.)6.4( )]TJ -15.6014 -1.1503 TD 0.0029 Tc -0.0072 Tw [(F)11.7(o)0.3(r)12( )-11.2(ea)11.4(ch)22.7( C)11(A)-1(S)11.7(,)7.2( )-11.2(w)21.3(e)0.2( )11.2(t)-9.5(r)0.9(a)11.4(i)1.7(n)11.5( a)11.4( b)11.5(i)1.7(n)11.5(a)0.2(r)-21.5(y)45( )-11.2(cla)11.4(s)1(s)12.2(i)1.7(fier)12( )11.2(\()-10.3(w)21.3(hich)11.5( i)12.9(s)12.2( )]TJ T* -0.0087 Tc 0.0379 Tw [(b)-11.3(a)-0.2(s)-21.7(e)-0.2(d on ve)-11.4(c)-11.4(t)-9.9(or )-11.2(s)-10.6(p)11.1(a)-11.4(c)-11.4(e)-0.2( 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The)11.6(n)11.7( )-11.2(f)12.2(o)11.7(r)12.2( )]TJ T* 0.0022 Tc 0.0717 Tw [(each)22( occ)10.7(u)-0.4(r)11.3(r)0.2(enc)10.7(e)10.7( )-11.1(of)22.5( a)10.7( CAS)11( )11.2(in)10.8( the)10.7( i)-10.2(n)22(itia)10.7(l seg)10.8(m)9.6(en)10.8(t)-10.2(e)-0.5(d)22( )]TJ 0 -1.1503 TD -0.0087 Tc 0.0267 Tw [(t)-9.9(r)-10.7(ai)-21.1(ni)-9.9(ng dat)-21.1(a)10.9(,)-15.6( )22.3(t)-21.1(h)-0.1(e cor)-10.7(r)-10.7(e)-11.4(s)-10.6(pond)-11.3(i)-9.9(n)-11.2(g )11.1(cl)-9.9(a)-11.4(s)0.6(s)-10.6(i)-21.1(fie)-11.4(r)0.4( is )11.1(u)-11.3(s)0.6(e)-11.4(d)-0.1( )11.1(t)-21.1(o)11.1( )]TJ T* 0.1273 Tw [(d)-11.4(e)-0.3(t)-21.2(e)-0.3(r)-10.8(m)-1.4(i)-10(n)-11.4(e w)9.6(h)-11.4(et)-10(h)-11.3(e)-0.4(r or n)-11.4(o)-0.2(t )11.1(t)-10(h)-11.4(e )11.1(CA)-12.7(S s)-10.7(h)-0.2(o)-11.4(u)-0.2(l)-21.2(d)11( be )11.1(s)-10.7(e)-11.5(g-)]TJ 0 -1.1391 TD -0.0074 Tc 0 Tw [(me)-10.1(n)-10(t)-8.6(e)-10.1(d)1.2(.)-14.3( )]TJ 1.2843 -1.1503 TD -0.0086 Tc 0.0936 Tw [(Fo)-11.2(r t)-21(h)11.2(e)-11.3( s)-10.5(e)-11.3(con)-11.2(d)0( p)-11.2(r)-10.6(ob)-11.2(l)-9.8(e)-11.3(m)10(,)-4.3( )11.1(t)-21(hou)-11.2(gh)-11.1( w)9.8(e)-11.3( c)-11.3(a)-11.3(n)0( si)-9.8(mp)-11.1(l)-32.1(y)22.3( )]TJ -1.2843 -1.1391 TD -0.0088 Tc 0.038 Tw [(u)-11.4(s)-10.7(e th)-11.4(e fi)-21.2(n)11(i)-21.2(te)-11.5(-s)-10.7(t)-21.2(a)10.8(t)-21.2(e)-0.4( ma)-11.5(ch)-11.4(i)-10(n)-11.4(es)-10.7( )11.2(d)-11.4(e)-11.5(sc)-11.5(ri)-10(b)-11.4(e)-11.5(d )11.2(i)-10(n)-0.2( )-11.2(Sec)-11.5(t)1.2(i)-21.2(on )-11.2(5)22.1( )]TJ T* -0.0086 Tc 0.049 Tw [(\()-10.6(e)-11.3(xt)-9.8(e)-11.3(n)-11.2(ded b)-22.3(y)22.4( u)-11.2(s)0.7(i)-9.8(n)-11.2(g )11.2(t)-21(h)0(e l)-9.8(o)-11.2(ng)11.2(e)-11.3(s)-10.5(t)-21(-)0.5(ma)-11.3(t)-9.8(c)-11.3(h)-11.2(i)-9.8(n)-11.2(g)11.2( c)-11.3(ons)-21.6(tr)-10.6(ai)-9.8(n)-11.2(t)12.5( )]TJ 0 -1.1503 TD 0.0019 Tc 0.0831 Tw [(f)11(o)-0.7(r d)10.5(i)0.7(sam)9.3(b)10.5(ig)10.5(uati)11.9(on\))11( )11.1(t)-10.5(o)10.5( d)21.7(e)-0.8(t)-10.5(e)10.4(ct)11.9( f)11(act)11.9(oid)10.5(s)11.2( )-11.2(in)10.5( )11.1(the)10.4( )11.1(in)10.5(itial)23( )]TJ T* 0.0027 Tc -0.007 Tw [(seg)11.3(m)10.1(en)11.3(t)-9.7(e)0(d)22.5( )-11.2(co)22.5(r)-10.5(p)11.3(us)12(, )11.2(our)11.8( m)10.1(e)11.2(t)12.7(hod )11.2(of)11.8( N)10(E)10.6(R in)11.3( the)11.2( )11.2(ini)12.7(t)-9.7(i)12.7(a)0(l)12.7( )]TJ 0 -1.1391 TD 0.0021 Tc 0.0606 Tw [(step)10.7( \()11.2(i)0.9(.)-4.8(e)10.6(.)6.4( )-11.2(s)11.4(t)0.9(ep)10.7( 1)10.7(\))0.1( )11.2(is)11.4( )-11.2(a)10.6( l)12.1(ittle)10.6( m)9.5(o)10.7(r)-11.1(e)-0.6( )11.2(co)10.7(mp)10.7(lica)10.6(t)0.9(ed)10.7(.)6.4( Fi)12.1(r)-11.1(s)11.4(t)12.1(,)6.4( )]TJ 0 -1.1503 TD 0.2058 Tw [(w)20.5(e)-0.6( )-11.1(m)9.5(a)-0.6(nu)10.7(a)10.6(l)-10.3(l)-10.3(y)33( )-11.1(a)10.6(nno)10.7(ta)10.6(te)10.6( na)10.6(m)9.5(e)-0.6(d)10.7( )-11.1(e)10.6(n)10.7(t)-10.3(i)12.1(ti)-10.3(e)21.7(s)0.2( on)10.7( a)10.6( sm)9.5(al)12.1(l)12.1( )]TJ 0 -1.1391 TD 0.0384 Tw [(sub)10.6(s)0.1(e)10.5(t)0.8( \(c)10.5(al)12(l )]TJ /F6 1 Tf 4.8357 0 TD 0.0022 Tc 0.0382 Tw [(se)10.7(ed)10.8( se)10.7(t)]TJ /F5 1 Tf 3.1605 0 TD 0.0024 Tc 0.038 Tw [(\))11.5( )-11.1(o)11(f)0.4( )11.2(the)10.9( tra)10.9(i)1.2(ni)12.4(ng)11( dat)12.4(a)10.9(.)6.7( Then)11(,)6.7( w)20.8(e)10.9( )]TJ -7.9962 -1.1391 TD -0.0088 Tc 0.0603 Tw [(o)-11.4(b)-0.2(t)-21.2(a)-0.3(i)-10(n)-0.2( a )11.1(c)-11.5(o)-11.4(nt)-10(e)-11.5(x)-0.2(t mo)-11.4(d)-11.4(e)-0.3(l on t)-10(h)-0.2(e )-11.2(s)-10.7(eed s)-10.7(e)-0.4(t)-10( )11.1(\()-10.8(c)-0.3(a)-11.5(l)1.2(l)-21.2(e)-11.5(d)]TJ /F6 1 Tf 18.4827 0 TD 0.0025 Tc 0.049 Tw [( seed)33.4( )]TJ -18.4827 -1.1615 TD 0.0029 Tc 0 Tw [(mode)22.5(l)]TJ /F5 1 Tf 2.4458 0 TD 0.0023 Tc 0.0492 Tw [(\))11.4(.)6.6( W)8.2(e)-0.4( thu)22.1(s)0.4( im)9.7(prov)10.9(e )11.1(t)12.3(h)-0.3(e c)10.8(ontex)10.9(t)12.3( )-11.2(m)20.9(o)-0.3(de)10.8(l)12.3( )-11.2(w)9.6(h)10.9(i)-10.1(c)-0.4(h)22.1( )]TJ -2.4458 -1.1391 TD 0.0024 Tc -0.0067 Tw [(is tr)11.5(ain)11(e)-0.3(d)11( on )11.2(the)10.9( ini)12.4(tial)12.4( ann)11(o)11(t)-10(at)12.4(ed)11( t)12.4(r)-10.8(ai)12.4(ning)11( co)11(rpu)22.2(s)0.5( )-11.2(by)33.3( )]TJ T* 0.002 Tc -0.0175 Tw [(inte)10.5(rpo)10.6(l)0.8(a)10.5(t)0.8(i)-10.4(n)10.6(g)10.6( it)12( )-11.2(w)20.4(i)0.8(t)-10.4(h)21.8( the)10.5( s)11.3(e)-0.7(e)10.5(d)-0.6( m)9.4(o)-0.6(de)10.5(l)12(.)-4.9( Fi)12(nal)12(l)-10.4(y)33(,)-16( w)20.4(e)-0.7( )-11.2(u)21.8(s)0.1(e)10.4( )]TJ 0 -1.1503 TD 0.0022 Tc 0.027 Tw [(the)10.7( )-11.2(im)9.6(p)10.8(r)0.2(ov)10.8(ed con)22(t)-10.2(ex)22(t )-11.2(m)9.6(o)-0.3(de)10.7(l i)-10.2(n)22( )-22.3(s)11.5(t)1(ep)10.8(s)11.5( )-11.2(2)10.8( )-11.2(and)10.8( 3 of)11.3( t)-10.2(h)10.8(e)10.7( )]TJ 0 -1.1391 TD 0.0025 Tc 0.1719 Tw [(bo)11.1(ots)11.8(t)-9.9(r)11.6(a)-0.2(pp)11.1(ing)22.3(.)-4.4( Ou)11.1(r)11.6( )-11.1(ex)11.1(p)11.1(e)-0.2(r)11.6(i)1.3(m)9.9(e)-0.2(nts)11.8( sho)11.1(w)9.8( )-11.1(t)12.5(h)-0.1(at)12.5( a)11( rel)12.5(a)-0.2(-)]TJ 0 -1.1503 TD 0.1942 Tw [(tiv)11.1(el)-9.9(y)33.5( sm)9.9(al)-9.9(l)12.5( )11.2(seed)22.3( )11.2(set )11.2(\(e)11(.g)11.1(.)6.8(,)-4.4( 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)11.2(pos)11.6(sib)10.9(l)1.1(e)10.8( )11.2(i)-10.1(n)10.9(to)10.9( w)20.7(o)-0.3(r)11.4(d)-0.3(s)11.6( t)12.3(h)-0.3(at)12.3( a)10.8(r)0.3(e)10.8( s)11.6(t)1.1(o)10.9(r)0.3(ed)10.9( )11.2(in)10.9( )11.2(our)11.4( )]TJ 0 -1.1503 TD -0.0084 Tc 0.0823 Tw [(l)-20.8(e)-11.1(x)11.4(i)-20.8(c)-11.1(on,)-15.3( a)-11.1(nd )11.2(t)-20.8(a)-11.1(g)11.4( )-11.1(on)-11(l)-20.8(y)33.7( )-11.1(t)-9.6(h)-11(e)-11.1( new w)10(o)-11(r)-10.4(d)-11(s)-10.3(,)-15.3( )-11.1(w)10(h)-11(i)-9.6(c)-11.1(h ot)-9.6(h)-11(e)-11.1(r)-10.4(-)]TJ 0 -1.1391 TD 0.0022 Tc 0.4067 Tw [(w)9.5(i)1(se w)9.5(o)10.8(uld)10.8( )-11.2(b)22(e)10.7( )-11.2(s)11.5(e)-0.5(g)22(m)-1.5(e)10.7(n)-0.4(t)-10.2(e)21.8(d in)10.8(to)10.8( s)11.5(t)-10.2(r)11.3(i)1(ng)10.8(s)11.5( of)22.5( one)10.7( )]TJ T* 0.0024 Tc 0.306 Tw [(-ch)11(a)-0.3(rac)10.9(t)1.2(e)10.9(r)0.4( w)20.8(o)-0.2(rds)11.7(.)-4.5( )11.2(When)22.2( t)12.4(h)-0.2(ere)10.9( ar)11.5(e)10.9( mu)11(ltip)11(le)10.9( seg)11(-)]TJ 0 -1.1615 TD 0.0022 Tc 0.1498 Tw [(m)9.6(e)-0.5(ntation)10.8(s)11.5( f)11.3(o)-0.4(r)11.3( a)10.7( se)10.7(nte)10.7(n)-0.4(c)10.7(e)10.7(,)-4.7( w)20.6(e)-0.5( k)10.8(eep)22( on)10.8(l)-10.2(y)33.2( one )11.1(tha)10.7(t)12.2( )]TJ 0 -1.1391 TD 0.0023 Tc 0.0604 Tw [(conta)10.8(i)1.1(ns)11.6( t)-10.1(h)10.9(e)21.9( )-22.3(le)10.8(as)11.6(t)12.3( )-11.2(num)9.7(be)10.8(r)11.4( of)11.4( )-11.2(w)9.6(o)10.9(r)-10.9(d)10.9(s)11.6(.)-4.6( T)-12.1(h)10.9(e)10.8( anno)10.9(ta)10.8(ted)10.9( )]TJ T* 0.0019 Tc 0.072 Tw [(t)-10.5(e)-0.8(s)11.2(t)11.9( )-11.1(s)11.2(e)-0.8(t)11.9( )-11.1(co)10.5(n)10.5(t)0.7(a)10.4(i)-10.5(n)10.5(s)0( in)10.5( to)10.5(ta)10.4(l )-11.1(24)21.7(7,)-16.1(0)21.7(3)-0.7(9)10.5( tok)10.5(e)-0.8(ns)11.2( \(in)10.5(c)-0.8(lu)10.5(ding)21.7( )]TJ 0 -1.1503 TD -0.0081 Tc 0.1155 Tw [(2)-10.7(0)-10.7(5)0.5(,)-15(1)-10.7(6)-10.7(2)11.7( l)-9.3(e)-10.8(xi)-9.3(c)-10.8(o)-10.7(n)11.7(/)-20.5(mo)-10.7(r)-10.1(p)-10.7(h-l)-9.3(e)-10.8(xi)-9.3(c)-10.8(on wor)-21.3(d)0.5(s,)-15( 4,3)-10.7(4)-10.7(7)0.5( P)11.8(N)-23.2(s, )]TJ 0 -1.1391 TD 0.026 Tw [(5)-10.6(,)-14.9(31)-10.6(1 )11.1(LN)-11.9(s, 3,8)-10.6(5)-10.6(0)11.8( )11.1(ON)-11.9(s,)-14.9( )11.1(an)-10.6(d)11.8( 6,)-14.9(63)-10.6(0)11.8( fa)-10.7(c)-10.7(t)2(o)-10.6(i)-9.2(ds, et)-9.2(c.)-14.9(\))-10( )]TJ 1.2843 -1.1503 TD 0.0025 Tc 0.0379 Tw [(Our)11.6( s)-10.5(y)33.5(stem)9.9( i)-9.9(s)11.8( m)9.9(eas)11.8(ure)11(d)-0.1( )11.2(thr)11.6(oug)22.3(h mu)11.1(l)-9.9(t)12.5(ipl)12.5(e)-0.2( p)11.1(r)-10.7(e)11(c)11(i)-9.9(-)]TJ -1.2843 -1.1503 TD -0.0085 Tc -0.007 Tw [(s)-10.4(i)-20.9(on)-11.1(-r)-21.7(ecal)-20.9(l \()-21.7(P)11.4(/)-9.7(R)-11.6(\) )-11.2(pai)-20.9(r)-10.5(s, )-11.2(and)-11.1( F-m)-12.2(e)0(a)-11.2(s)-10.4(u)-11.1(r)-10.5(e)-11.2(s)0.8( \()-10.5(F)]TJ /TT5 1 Tf 6.7744 0 0 6.7744 249.1209 393.2788 Tm 0 Tc 0 Tw (!)Tj /F5 1 Tf 0.496 0 TD 0.0028 Tc (=1)Tj 10.7452 0 0 10.7452 259.6809 394.7188 Tm 0.0069 Tc -0.0112 Tw [(, w)25.3(h)4.3(i)5.7(c)4.2(h)26.7( )]TJ -17.634 -1.1391 TD 0.0023 Tc -0.0178 Tw [(i)-10.1(s)11.6( def)11.4(i)1.1(ne)10.8(d )11.1(as)11.6( )-11.2(2)10.9(P)11.1(R/\(P+)19.1(R)-11.9(\))11.4(\))0.3( fo)22.1(r)-10.9( e)10.8(ach)22.1( )-11.2(w)20.7(o)-0.3(rd c)10.8(l)-10.1(a)21.9(ss.)6.6( Sin)10.9(c)-0.4(e)10.8( )]TJ T* 0.002 Tc -0.0286 Tw [(t)-10.4(h)10.6(e)10.5( a)10.5(n)-0.6(n)10.6(o)-0.6(t)12(a)-0.7(ted)21.8( t)12(e)-0.7(s)11.3(t)12( se)10.5(t)12( )11.2(is)11.3( b)21.8(a)-0.7(se)10.5(d )11.2(o)10.6(n)10.6( a)21.6( )11.2(par)11.1(tic)10.5(ula)10.5(r)0( )22.4(lex)10.6(i)0.8(con)10.6(,)17.5( )]TJ T* 0.0023 Tc 0.1609 Tw [(som)9.7(e)10.8( of)22.6( th)10.9(e)10.8( ev)10.9(alu)10.9(a)-0.4(t)12.3(i)1.1(on)10.9( m)9.7(e)10.8(asur)11.4(es)11.6( )11.2(are)10.8( m)20.9(ean)10.9(ing)10.9(l)1.1(ess)22.8( )]TJ 0 -1.1503 TD 0.0022 Tc 0.0382 Tw [(w)9.5(h)10.8(en w)9.5(e)-0.5( )11.2(com)9.6(p)10.8(ar)11.3(e)10.7( )-11.1(o)10.8(u)10.8(r)11.3( s)-10.8(y)33.2(stem)9.6( )11.2(t)-10.2(o)22( oth)10.8(e)-0.5(r)11.3( )11.2(s)-10.8(y)33.2(stem)9.6(s)11.5( )-11.1(th)10.8(at)12.2( )]TJ T* 0.0023 Tc 0.1162 Tw [(use)10.8( dif)11.4(f)0.3(eren)22.1(t l)12.3(e)-0.4(x)10.9(i)1.1(cons)11.6(.)6.6( So)10.9( i)12.3(n)-0.3( com)9.7(p)10.9(a)10.8(r)0.3(ison)10.9( w)20.7(i)1.1(t)-10.1(h)22.1( di)-10.1(f)11.4(-)]TJ 0 -1.1391 TD 0.0022 Tc 0.5854 Tw [(fe)10.7(r)-11(e)-0.5(n)10.8(t)1( sy)44.3(s)-10.8(t)1(em)9.6(s,)6.5( w)20.6(e)-0.5( con)10.8(s)0.3(ide)10.7(r)11.3( only)33.2( the )11.2(p)10.8(r)-11(e)21.8(c)-0.5(i)-10.2(-)]TJ 0 -1.1503 TD -0.0086 Tc 0.0936 Tw [(s)-10.5(i)-21(on)-11.2(-r)-21.8(ecal)-21(l o)-11.2(f)0.5( N)-12.5(E)-0.7(R )-11.2(a)-11.3(nd t)-21(h)0(e )-11.2(nu)-11.2(mb)-11.2(e)-11.3(r)0.5( o)-11.2(f)0.5( O)-12.5(A)-12.5(S)11.3( )-11.2(e)-11.3(r)0.5(r)-10.6(o)-11.2(rs )]TJ 0 -1.1391 TD 0.003 Tc 0.0709 Tw [(\()-10.2(i)13(.e)11.5(. )11.2(cro)11.6(ssi)13(ng)11.6( br)12.1(ack)22.8(et)-9.4(s)12.3(\))12.1( bec)11.5(a)0.3(u)11.6(s)1.1(e)11.5( thes)12.3(e)11.5( m)10.4(easu)11.6(r)1(es)12.3( )11.2(are)22.6( )]TJ T* -0.0088 Tc 0.2055 Tw [(l)-21.2(e)-11.5(x)11(i)-21.2(c)-11.5(on in)-11.4(d)-11.4(e)-11.5(pe)-11.5(nd)-11.4(e)-11.5(n)-0.2(t a)-11.5(n)-11.4(d )22.3(t)-10(h)-11.4(er)-22(e )11.2(i)-10(s)0.5( al)-10(w)9.6(a)-22.7(y)11(s)-10.7( a)-11.5( )11.2(s)-10.7(i)-10(n)-11.4(g)-0.2(l)-10(e)-0.3( )]TJ 0 -1.1615 TD 0.0029 Tc 0.0151 Tw [(unam)10.3(b)0.3(ig)11.5(uo)11.5(us)12.2( a)22.5(n)0.3(sw)10.2(e)11.4(r)0.9(. )]TJ 1.2843 -1.1391 TD 0.0023 Tc 0.0939 Tw [(T)-12.1(h)10.9(e)10.8( tra)10.8(i)1.1(n)10.9(i)1.1(ng)10.9( cor)11.4(pus)11.6( f)11.4(o)-0.3(r)11.4( co)10.9(ntex)10.9(t m)9.7(o)-0.3(d)10.9(e)-0.4(l)12.3( con)10.9(t)1.1(a)10.8(i)1.1(ns)11.6( )]TJ -1.2843 -1.1391 TD 0.1051 Tw [(approx)10.9(im)9.7(at)12.3(el)-10.1(y)33.3( 80)10.9( m)9.7(ill)12.3(ion)10.9( )22.4(C)-11.9(h)22.1(i)-10.1(n)10.9(es)11.6(e)10.8( ch)10.9(ara)10.8(c)-0.4(t)12.3(e)-0.4(r)-10.9(s)11.6( f)22.6(r)0.3(om)9.7( )]TJ 0 -1.1503 TD -0.0081 Tc -0.0074 Tw [(va)-10.8(r)-10.1(i)-20.5(ou)-10.7(s d)11.7(o)-10.7(ma)-10.8(i)-9.3(n)0.5(s o)-10.7(f)12.2( )11.1(t)-9.3(e)0.4(xt)-20.5( )22.3(s)-10(u)-10.7(ch)-10.7( )22.3(a)-10.8(s)1.2( )11.1(ne)-10.8(w)10.3(s)-10(p)-10.7(a)-10.8(p)-10.7(e)-10.8(rs, n)-10.7(ove)-10.8(ls)-10(, )]TJ 0 -1.1391 TD 0.0025 Tc 0.049 Tw [(m)9.9(a)-0.2(g)11.1(azines)11.8( )11.1(et)-9.9(c)22.1(.)-4.4( )11.1(Th)11.1(e)11( t)12.5(r)0.5(ain)11.1(i)1.3(n)11.1(g)11.1( cor)11.6(pora)11( f)11.6(o)11.1(r)11.6( )-11.2(c)22.1(l)-9.9(a)11(s)0.6(s)11.8( m)9.9(od-)]TJ 0 -1.1503 TD -0.0087 Tc 0.0044 Tw [(e)-11.4(l)-21.1(s a)-11.4(r)-10.7(e d)-11.3(e)-11.4(s)-10.6(c)-0.2(r)-10.7(i)-9.9(be)-11.4(d i)-21.1(n)-0.1( )-11.2(S)-11.1(e)10.9(c)-11.4(t)-9.9(i)-9.9(o)-11.3(n )-11.2(5.)-15.6( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 70.201 185.0788 Tm 0.0034 Tc 0 Tw [(7.)6.8(1)]TJ /F2 1 Tf 1.2534 0 TD 0 Tc ( )Tj /F3 1 Tf 1.1096 0 TD -0.0024 Tc -0.001 Tw [(Syste)-20.7(m)8.7( res)-14.1(u)9.1(l)-12.1(ts )]TJ /F5 1 Tf 10.7452 0 0 10.7452 70.201 166.9588 Tm 0.003 Tc 0.0039 Tw [(O)-12.1(u)11.6(r s)-10(y)34(stem)10.4( i)-9.4(s)12.3( des)12.3(i)1.8(g)11.6(n)0.4(ed)11.6( in)11.6( the)22.6( )-22.3(w)21.4(a)-10.9(y)34( )-11.1(that)13( )-11.1(co)11.6(mp)11.6(onen)11.6(t)1.8(s)12.3( )]TJ 0 -1.1391 TD 0.0026 Tc 0.0378 Tw [(such)11.2( as)11.9( fac)22.2(t)-9.8(oi)12.6(d d)11.2(e)-0.1(t)12.6(ect)12.6(or)11.7( an)11.2(d )11.2(N)9.9(E)-0.6(R c)11.1(a)-0.1(n)11.2( be)11.1( )11.2()-10.6(s)0.7(w)21(i)1.4(t)-9.8(c)11.1(he)11.1(d)11.2( )]TJ T* -0.009 Tc 0.161 Tw [(o)-11.6(n)-11.6( or o)-11.6(ff,)-27( )11.1(s)-10.9(o)-0.4( th)-11.6(a)-11.7(t)1( w)9.4(e)-11.7( )11.1(c)-11.7(a)-11.7(n)-0.4( in)-11.6(ve)-11.7(s)-10.9(t)-10.2(i)-10.2(g)-0.4(a)-11.7(t)1(e t)-21.4(h)10.8(e r)-11(e)-0.5(l)-21.4(a)-0.5(t)-10.2(i)-10.2(v)-0.4(e )]TJ 0 -1.1503 TD 0.0025 Tc 0.0155 Tw [(cont)12.5(ri)-9.9(b)11.1(u)11.1(tion)22.3( of)22.8( ea)11(ch)11.1( )11.1(com)9.9(p)-0.1(o)22.3(n)-0.1(ent)12.5( to)11.1( )11.1(t)12.5(h)-0.1(e)11( )11.1(ov)11.1(eral)12.5(l w)20.9(o)-0.1(rd)11.1( )]TJ 0 -1.1391 TD [(seg)11(m)9.8(entat)12.4(i)-10(on)22.2( p)22.2(e)-0.3(r)-10.8(f)11.5(orm)9.8(a)-0.3(n)11(c)10.9(e)10.9(.)-4.5( )22.3( )]TJ 23.1397 46.38 TD 0.0022 Tc 0.2727 Tw [(The)10.7( m)9.6(a)10.7(in )22.3(r)-11(e)10.7(su)10.8(lts)11.5( ar)11.3(e )11.2(sh)10.8(o)10.8(w)20.6(n in )11.2(Tab)10.8(l)1(e)10.7( 1)10.8(.)6.5( F)11(o)-0.3(r)11.3( )]TJ -1.2843 -1.1391 TD 0.0124 Tc 0.1173 Tw [(c)9.7(o)21(m)8.7(p)21(a)9.7(r)21.5(is)10.5(o)9.8(n)32.2(,)5.5( w)30.8(e)9.7( a)20.9(l)11.2(s)10.5(o)21( )11.2(in)21(c)20.8(l)0(u)32.2(d)9.8(e)9.7( )11.2(i)11.2(n)21( th)32.2(e)20.9( ta)20.9(b)21(l)0(e)20.9( )11.2(\()21.5(R)9.3(o)9.8(w)30.8( 1)9.8(\))21.5( )]TJ 0 -1.1503 TD -0.0087 Tc 0.1496 Tw [(t)-9.9(h)-11.3(e re)-11.4(s)-10.6(u)-0.1(l)-9.9(t)1.3(s )-11.1(of)-10.7( u)11.1(s)-10.6(i)-21.1(ng )11.2(t)-21.1(h)-0.1(e gre)-11.4(e)-11.4(d)-22.4(y)22.3( s)-10.6(e)-11.4(gme)-11.4(n)-0.1(t)-21.1(o)-0.1(r)-10.7( \()-10.7(F)11.2(M)-13.1(M)-2(\) )]TJ T* -0.0195 Tc 0.1269 Tw [(d)-22.1(e)-11(s)-32.5(c)0.1(r)-32.7(i)-20.7(b)-10.9(e)-22.2(d )-22.3(i)-20.7(n)-10.9( 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r)-10.7(e)-0.2(c)-11.4(a)-0.2(l)-9.9(l)1.3(,)-15.6( b)-11.3(u)11.1(t)-9.9( th)-11.3(e p)11.1(r)-21.9(e)-11.4(c)10.9(i)-21.1(s)0.6(i)-9.9(o)-11.3(n)-11.2(s)0.6( ar)-10.7(e not)-9.9( v)11.1(e)-11.4(r)-21.9(y)22.2( go)-11.2(o)-11.3(d)-0.1( )]TJ 0 -1.1391 TD 0.0023 Tc 0.2838 Tw [(be)10.8(cau)10.9(se)10.8( )-11.1(th)10.9(e)-11.6(y)33.3( canno)10.9(t )11.2(i)-10.1(d)10.9(en)10.9(tify)33.3( correc)10.8(t)-10.1(l)-10.1(y)33.3( unk)10.9(no)10.9(w)9.6(n)-0.3( )]TJ 0 -1.1503 TD 0.0022 Tc 0.0605 Tw [(w)20.6(o)-0.4(rds th)10.8(at)12.2( )-11.2(ar)11.3(e n)10.8(o)10.8(t)1( in)10.8( )11.2(t)-10.2(h)10.8(e)10.7( )-11.2(le)10.7(x)10.8(i)1(con)10.8( )-11.2(su)22(ch fa)21.8(ct)-10.2(o)10.8(i)1(ds)11.5( and)33.1( )]TJ 0 -1.1391 TD 0.0031 Tc 0.1713 Tw [(na)11.6(me)11.6(d ent)13.1(i)-9.3(t)13.1(i)1.9(es)12.4(. )11.2(We)11.6( )-11.1(a)11.6(l)1.9(so)11.7( )-11.1(f)12.2(i)1.9(n)11.7(d)0.6( tha)11.6(t)1.9( ev)11.7(en )-11.1(u)11.7(s)1.2(ing)22.9( t)-9.3(h)11.7(e)11.6( )]TJ T* -0.0085 Tc 0.2275 Tw [(s)-10.4(a)-11.2(me l)-9.7(e)-11.2(xi)-9.7(c)-11.2(o)-11(n)11.3(,)-15.4( our a)-11.2(p)-11.1(p)-11.1(r)-10.5(oa)-11.2(ch)11.3( )-11.2(t)-9.7(h)0.1(a)-11.2(t)-9.7( )11.1(i)-9.7(s)0.8( )-11.2(b)11.3(a)-11.2(s)-10.4(e)-11.2(d o)-11.1(n)11.3( t)-20.9(h)11.3(e )]TJ 0 -1.1615 TD 0.0023 Tc 0.1832 Tw [(im)9.7(prov)10.9(ed)22.1( )-11.2(so)10.9(urc)10.8(e)-0.4(-)11.4(c)-0.4(hann)10.9(e)10.8(l)1.1( )11.1(mo)10.9(dels)11.6( outp)10.9(e)-0.4(rf)11.4(orm)9.7(s)11.6( t)-10.1(h)22.1(e)10.7( )]TJ 0 -1.1391 TD 0.0021 Tc 0.3621 Tw [(g)10.7(r)0.1(eedy)33.1( ap)10.7(proach)10.7( )11.1(\(w)9.4(ith)10.7( a)21.7( s)11.4(l)0.9(i)-10.3(g)21.9(ht )11.1(but)12.1( )11.1(sta)10.6(t)0.9(i)12.1(s)0.2(tica)10.6(l)0.9(l)-21.4(y)44.2( )]TJ T* -0.0082 Tc 0.0374 Tw [(s)-10.1(i)-9.4(gn)-10.8(i)-9.4(f)0.9(i)-20.6(c)0.3(a)-10.9(n)0.4(t di)-9.4(ffe)-10.9(r)-10.2(e)-10.9(nt i.e.)-15.1(, )]TJ /F6 1 Tf 9.8835 0 TD 0 Tc 0 Tw (P)Tj /F5 1 Tf 0.6031 0 TD 0.0027 Tc 0.0042 Tw [( <)8.3( )-11.1(0)11.3(.)-15.3(0)11.3(1)11.3( acco)11.3(rdi)12.7(n)0.1(g)11.3( to)11.3( )-22.3(t)12.7(h)0.2(e)11.1( )]TJ /F6 1 Tf 9.783 0 TD 0 Tc 0 Tw (t)Tj /F5 1 Tf 0.268 0 TD ( )Tj -20.5376 -1.1503 TD 0.0022 Tc 0.2615 Tw [(tes)11.5(t)1(\) bec)10.7(a)-0.5(us)11.5(e)10.7( t)-10.2(h)10.8(e)10.7( )-11.2(use)10.7( of)22.5( )-11.2(contex)10.8(t)12.2( )-22.4(m)20.8(o)-0.4(d)10.8(e)-0.5(l re)10.7(so)10.8(l)-10.2(v)22(es)11.5( )]TJ 0 -1.1391 TD 0.002 Tc 0.5633 Tw [(m)9.4(o)-0.6(re)10.5( am)9.4(big)10.6(u)10.6(itie)10.5(s)11.3( i)-10.4(n)21.8( se)21.6(g)10.6(m)9.4(entat)-10.4(i)0.8(on)21.8(.)-4.9( )11.2(T)9.9(h)-0.5(e)10.5( m)9.4(o)-0.5(s)11.3(t)12( )]TJ 0 -1.1503 TD 0.0023 Tc 0.3061 Tw [(prom)9.7(is)11.6(ing)10.9( prop)10.9(er)11.4(t)-10.1(y)33.2( )-22.3(of)11.4( )-11.2(ou)10.9(r)11.4( )-22.3(ap)10.9(p)10.9(r)0.3(oa)10.8(ch)10.9( )-11.2(is)11.6( t)-10.1(h)10.9(at t)-10.1(h)22.1(e)10.7( )]TJ T* -0.0085 Tc 0.2611 Tw [(s)-10.4(o)-11.1(ur)-21.7(c)11.1(e)-11.2(-)-10.5(c)-11.2(ha)-11.2(n)-11(n)0.1(e)-11.2(l)1.5( mo)-11.1(del)-20.9(s)0.8( )11.2(pro)-11.1(v)0.1(i)-9.7(d)-11.1(e)-11.2( )11.2(a)-11.2( fle)-11.2(x)0.1(i)-9.7(b)-11(l)-9.7(e)0( fra)-11.2(me)-11.2(-)]TJ 0 -1.1391 TD -0.0087 Tc 0.0491 Tw [(w)9.7(o)-11.3(r)-10.7(k)-0.1( )-11.1(w)9.7(h)-11.3(e)-11.4(r)-10.7(e)-11.4( a )-11.1(w)9.7(i)-9.9(d)-11.3(e)-11.4( va)-11.4(ri)-9.9(et)-32.2(y)33.4( )-22.3(of)-10.7( l)-9.9(i)-21.1(ngu)-11.3(is)-10.6(t)-9.9(i)-9.9(c)-0.2( kn)-11.3(owl)-9.9(e)-11.4(d)-11.2(g)11.1(e)-11.4( )]TJ T* 0.0023 Tc 0.0381 Tw [(an)10.9(d)10.9( s)11.6(t)1.1(at)12.3(isti)12.3(cal)12.3( m)9.7(o)-0.3(d)22.1(e)-0.4(ls)11.6( )11.2(can)10.9( )22.4(b)10.9(e)-0.4( )22.4(com)9.7(b)10.9(i)-10.1(n)10.9(ed)]TJ /F6 1 Tf 15.6796 0 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 0.2904 0 TD 0.0017 Tc 0.0163 Tw [(in)10.3( a)10.2( )-11.2(un)10.3(if)10.8(i)-10.7(e)-1(d)21.5( )]TJ -15.97 -1.1391 TD -0.019 Tc 0.104 Tw [(wa)-44(y)12(.)-25.9( )11.1(A)-34.1(s)-9.7( )11.1(s)-20.9(h)-21.6(o)-10.4(w)-11.7(n )-11.2(i)-20.2(n)-10.4( )11.1(R)-10.9(o)-21.6(ws)-20.9( 3 t)-20.2(o)-10.4( 6)-10.4(,)-14.7( 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)22.4(show)21(ing)11.2( )11.2(th)11.2(at)12.6( )]TJ -1.2843 -1.1391 TD 0.003 Tc 0.015 Tw [(86)11.6(.2)11.6(%)9.6( )-11.2(of)23.3( e)11.5(rro)11.6(rs)12.3( )-11.2(co)11.6(me)11.5( f)12.1(r)12.1(o)0.5(m)10.4( )11.1(NE)10.9(R and)22.8( )-11.2(f)12.1(a)0.3(c)11.5(t)1.8(oi)13(d)11.6( de)11.5(tec-)]TJ T* 0.0022 Tc -0.04 Tw [(tion)10.8(,)6.5( al)12.2(thoug)10.8(h)22( )-11.2(t)12.2(h)-0.4(e)10.7( to)10.8(k)10.8(e)-0.5(ns)11.5( of)11.3( thes)11.5(e)10.7( w)9.5(o)10.8(r)-11(d)10.8( t)-10.2(y)33.2(pes c)10.7(ons)11.5(ist)23.3( )]TJ 0 -1.1615 TD 0.0035 Tc 0.0034 Tw [(of)12.6( on)12.1(l)-8.9(y)34.5( 8.7)12.1(%)10.1( of)23.8( )-11.1(al)13.5(l)13.5( tha)12(t)13.5( are)12( )11.2(in)12.1( t)-8.9(h)23.3(e)12( )-11.1(t)13.5(e)0.8(st)13.5( se)12(t)13.5(.)-3.4( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 305.0409 246.6388 Tm -0.0068 Tc 0 Tw [(7.)-13.7(2)]TJ /F2 1 Tf 1.2432 0 TD 0 Tc ( )Tj /F3 1 Tf 1.1096 0 TD 0.0036 Tc 0.0033 Tw [(Com)14.7(p)4.8(ar)5.8(ison)15.1( wit)7.8(h)4.8( )10.3(oth)15.1(e)5.8(r)5.8( 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sp)10.9(ecif)11.4(i)1.1(ca)10.8(tion)10.9(s)11.6( u)10.9(s)0.4(ed)22.1( )-11.2(by)33.3( t)-10.1(h)10.9(es)11.6(e s)-10.7(y)44.4(st)-10.1(em)9.7(s,)6.6( )11.2(i)-10.1(t)12.3( )]TJ 0 -1.1503 TD -0.0093 Tc 0.1055 Tw [(i)-21.7(s)0( s)-11.2(t)0.7(i)-21.7(ll ve)-12(r)-22.5(y)21.7( d)-11.9(i)-10.5(ff)-11.3(i)-10.5(c)-12(u)-11.9(l)-10.5(t t)-21.7(o)-0.7( co)10.5(m)-13(p)-0.7(a)-12(r)-11.3(e )-11.2(t)-10.5(h)-0.7(e)-12(i)0.7(r)-11.3( )11.2(r)-11.3(e)-12(su)-11.9(lt)-21.7(s a)-12(u)-0.7(t)-10.5(o)-11.9(-)]TJ 0 -1.1838 TD 0.0024 Tc 0.1943 Tw [(m)9.8(a)-0.3(t)-10(i)1.2(c)10.9(a)-0.3(l)12.4(l)-10(y)33.4(.)-15.6( F)11.2(o)11(r)11.5( ex)11(am)9.8(ple)10.9(,)6.7( )]TJ /TT1 1 Tf 9.6942 0 0 9.6942 180.4809 415.2388 Tm 0.0398 Tc 0 Tw [(MN>)12.4(O)-12.4(P)]TJ /F5 1 Tf 5.199 0 TD 0 Tc ( )Tj 10.7452 0 0 10.7452 235.2009 415.2388 Tm 0.0021 Tc 0.1946 Tw [(Be)10.6(ijing)21.9( ci)12.1(t)-10.3(y)21.9( )]TJ -15.3558 -1.1614 TD -0.0087 Tc 0.0937 Tw [(go)-22.4(ve)-11.4(r)-10.7(n)-11.3(me)-11.4(nt)-9.9( 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[(sam)10.3(e)0.2( s)-10.1(y)33.9(stem)10.3(. Ev)11.5(en)11.5( w)21.3(o)0.3(rse)11.4(,)-4( )11.1(som)10.3(e)0.2( L)10.8(N)-1(s)12.2( )11.1(t)-9.5(a)11.4(g)11.5(g)11.5(e)0.2(d in)11.5( one)11.4( )]TJ 0 -1.1391 TD -0.0081 Tc 0.4058 Tw [(s)-21.1(y)22.9(s)-10(t)-20.5(em)-11.8( a)-10.8(r)1(e )11.1(t)-20.5(a)-10.8(g)11.7(g)0.5(e)-10.8(d)-10.7( as ON)-12(s i)-9.3(n)0.5( )11.1(a)-10.8(n)-10.7(ot)-9.3(h)-10.7(e)-10.8(r )11.1(s)-21.1(y)22.9(s)-10(t)-20.5(em)-11.8(. )]TJ T* 0.0022 Tc 0.1052 Tw [(T)-12.2(h)-0.4(e)10.7(r)0.2(ef)11.3(or)11.3(e)10.7(,)6.5( w)20.6(e)-0.5( )-11.1(h)10.8(a)-0.5(v)10.8(e)-0.5( )11.2(to)10.8( m)9.6(a)-0.5(n)10.8(u)-0.4(ally)33.2( check)10.8( the)10.7( )11.2(res)11.5(u)-0.4(l)12.2(t)-10.2(s)11.5(.)6.5( )]TJ 0 -1.1503 TD 0.0027 Tc 0.2945 Tw [(We )11.1(p)11.3(i)-9.7(ck)22.5(ed)11.3( 93)11.3(3)11.3( sen)11.3(t)1.5(en)11.3(c)11.2(e)0(s)12( at)12.7( r)11.8(a)0(ndo)11.3(m)10.1( )11.1(con)11.3(t)1.5(ai)12.7(ning)22.5( )]TJ T* 0.0025 Tc 0.183 Tw [(22,)6.8(833)11.1( w)20.9(o)-0.1(rds)11.8( \()11.6(i)1.3(nc)11(lud)11.1(i)1.3(ng)11.1( )11.1(3)11.1(29 P)22.4(N)-12.6(s)11.8(,)6.8( )11.1(617)22.3( L)10.4(N)-1.4(s)11.8(,)-4.4( )11.1(a)11(n)-0.1(d)11.1( )]TJ 0 -1.1391 TD -0.0084 Tc 0.0711 Tw [(4)-11(3)-11(5)0.2( ONs)-10.3(\))-10.4( fo)-11(r )11.2(t)-20.8(e)0.1(s)-10.3(t)1.6(i)-9.6(n)-11(g. )11.2(W)-13.7(e)0.1( )11.2(al)-20.8(s)-10.3(o)11.4( )-11.2(d)11.4(i)-20.8(d not)-9.6( di)-9.6(ffe)-11.1(r)-10.4(e)-11.1(nt)-20.8(i)-9.6(a)0.1(t)-9.6(e)0.1( )]TJ 0 -1.1503 TD 0.0028 Tc 0.3391 Tw [(L)10.7(N)-1.1(s )-11.2(an)22.6(d O)10.1(N)-1.1(s)12.1( in)11.4( ev)11.4(alua)11.3(t)12.8(i)-9.6(on)22.6(. )11.2(T)-11.6(h)11.4(a)11.3(t)-9.6( )11.2(i)-9.6(s)12.1(,)7.1( )-11.2(w)21.2(e)0.1( on)11.4(l)-9.6(y)22.6( )]TJ 0 -1.1391 TD 0.0025 Tc 0.0602 Tw [(check)11.1(ed)22.3( the)11( w)20.9(o)-0.1(rd)11.1( )11.2(bou)11.1(n)11.1(d)-0.1(ar)11.6(i)12.5(e)-0.2(s)11.8( )-11.2(o)11.1(f)11.6( L)21.6(N)-12.6(s)11.8( )11.2(and)22.3( O)9.8(N)9.8(s)11.8( )11.2(and)11.1( )]TJ T* 0.0028 Tc 0.3168 Tw [(t)-9.6(r)0.8(e)11.3(a)0.1(te)11.3(d bo)11.4(th)11.4( )-11.1(t)12.8(a)0.1(g)11.4(s)0.9( ex)11.4(chan)11.4(g)11.4(eabl)12.8(e)11.3(. Th)11.4(e res)12.1(u)0.2(l)12.8(t)1.6(s)12.1( )-11.1(ar)11.9(e)11.3( )]TJ 0 -1.1615 TD 0.0124 Tc 0.0056 Tw [(s)10.5(h)9.8(o)9.8(w)30.8(n)9.8( in)32.2( T)20.3(a)9.7(b)9.8(l)22.4(e)20.9( )-11.2(2)32.2(.)5.5( )11.1(W)7.1(e)20.9( c)20.9(a)9.7(n)21( s)21.7(e)9.7(e)20.9( th)32.2(a)9.7(t)11.2( )11.1(i)11.2(n)21( )11.1(th)9.8(i)22.4(s)21.7( s)10.5(m)19.8(a)9.7(l)11.2(l)22.4( )11.1(te)9.7(s)21.7(t)22.4( )]TJ 0 -1.1391 TD 0.0018 Tc 0 Tw (set )Tj /F3 1 Tf 1.463 0 TD -0.0199 Tc [(SC)-23.8(M)]TJ /F5 1 Tf 2.1889 0 TD 0.0023 Tc 0.0939 Tw [( )-11.2(a)21.9(c)-0.4(hi)12.3(ev)10.9(es)11.6( t)-10.1(h)22.1(e)10.8( be)10.8(st o)10.9(v)10.9(e)-0.4(r)11.4(a)-0.4(ll)12.3( pe)10.8(rf)11.4(orm)9.7(a)-0.4(nc)10.8(e)10.8( of)22.6( )]TJ -3.6519 -1.1391 TD 0.0157 Tw [(NE)10.2(R)10.4( and)22.1( )11.1(the)10.8( )22.3(bes)11.6(t)12.3( p)10.9(e)10.8(rfo)10.9(r)-10.9(m)9.7(a)10.8(n)10.9(ce)10.8( o)10.9(f)11.4( )11.1(re)10.8(solv)10.9(ing)10.9( )22.3(O)9.6(A)-12.8(S)22.2(.)-15.7( )]TJ /F3 1 Tf 11.6798 0 0 11.6798 70.201 204.3988 Tm 0 Tc 0 Tw (8)Tj /F2 1 Tf 0.5034 0 TD ( )Tj /F3 1 Tf 1.8596 0 TD -0.0012 Tc [(Co)-4.6(n)10.3(c)1(l)-10.9(u)0(sio)-4.6(n)10.3( )]TJ /F5 1 Tf 10.7452 0 0 10.7452 70.201 186.2788 Tm 0.0028 Tc 0.0041 Tw [(T)-11.6(h)0.2(e)11.3( co)11.4(n)11.4(t)1.6(ribu)11.4(t)12.8(i)1.6(ons)12.1( of)23.1( )-22.3(t)12.8(h)0.2(i)12.8(s)12.1( )-22.3(p)22.6(a)11.3(per)11.9( )-11.1(a)11.3(r)0.8(e)11.3( thr)11.9(ee-)11.9(f)11.9(o)0.2(ld)11.4(. )-11.1(F)11.6(i)1.6(r)11.9(s)0.9(t,)7.1( )]TJ 0 -1.1391 TD -0.0084 Tc 0.5178 Tw [(we)-11.1( fo)-11(r)-10.4(m)-1(u)-11(l)-9.6(at)-9.6(e )11.2(t)-20.8(h)11.4(e C)-11.5(h)0.2(i)-9.6(n)-11(es)-10.3(e w)10(o)-11(r)-10.4(d)0.2( )11.2(s)-10.3(e)-11.1(gme)-11.1(n)-11(t)-9.6(a)0.1(t)-9.6(i)-9.6(o)-11(n)11.4( )]TJ T* 0.0022 Tc 0.0605 Tw [(probl)12.2(em)20.8( as)11.5( a)10.7( s)11.5(e)-0.5(t)12.2( of)22.5( )-11.2(c)10.7(o)10.8(rrela)10.7(t)12.2(e)-0.5(d)10.8( pro)10.8(b)-0.4(lem)9.6(s)11.5(,)6.5( )-11.2(w)20.6(h)-0.4(ic)10.7(h)10.8( a)10.7(r)0.2(e)10.7( )]TJ 0 -1.1615 TD 0.002 Tc 0.6414 Tw [(better)11.1( )-11.2(so)21.8(l)-10.4(v)10.6(e)10.5(d)-0.6( sim)9.4(u)-0.6(ltan)10.6(e)-0.7(o)21.8(u)-0.6(sl)-10.4(y)33(,)-16( inc)10.5(l)0.8(ud)10.6(i)-10.4(n)10.6(g)10.6( )-11.2(w)20.4(o)-0.6(rd)10.6( )]TJ 0 -1.1391 TD -0.0082 Tc 0.0486 Tw [(b)-10.8(r)-10.2(e)-10.9(a)-10.9(k)0.4(i)-9.4(n)-10.8(g, m)-11.9(o)11.6(r)-21.4(p)0.4(h)-10.8(o)0.4(l)-9.4(o)-10.8(gi)-9.4(c)-10.9(a)0.3(l )-11.1(a)11.4(n)0.4(a)-10.9(l)-20.6(y)22.8(s)-10.1(i)-20.6(s)-10.1(, f)-10.2(act)-20.6(oi)-9.4(d de)-10.9(te)-10.9(c)-10.9(t)1.8(i)-9.4(o)-10.8(n )]TJ T* 0.0151 Tw [(a)-10.9(n)-10.8(d )11.2(NE)-11.4(R.)-15.1( )11.2(S)-10.6(e)-10.9(c)-10.9(ond, )-11.1(w)10.2(e)0.3( pr)-10.2(e)-10.9(s)1.1(en)-10.8(t a u)-10.8(n)11.6(i)-20.6(f)0.9(i)-9.4(e)-10.9(d )11.2(a)-10.9(p)0.4(p)-10.8(r)-10.2(oa)-10.9(c)-10.9(h)11.6( t)-9.4(o)0.4( )]TJ 0 -1.1503 TD 0.0023 Tc 0.0827 Tw [(t)-10.1(h)10.9(es)11.6(e)10.8( p)22.1(r)-10.9(o)10.9(b)-0.3(l)12.3(e)-0.4(m)9.7(s)11.6( u)10.9(s)0.4(ing)33.3( th)10.9(e)10.8( )11.1(i)12.3(m)9.7(prov)10.9(ed)10.9( )11.1(sou)22.1(r)0.3(ce-c)10.8(h)-0.3(a)10.8(nnel)23.4( )]TJ 21.8554 49.3059 TD -0.0083 Tc 0.272 Tw [(mo)-10.9(de)-11(l)-20.7(s)1(. T)-11.5(h)-10.9(e )-11.2(mo)-10.9(d)11.5(e)-11(l)-20.7(s)1( pr)-10.3(o)-10.9(v)0.3(i)-9.5(d)-10.9(e )-11.2(a si)-20.7(mp)-10.9(l)-9.5(e)0.2( )-11.2(st)-9.5(at)-9.5(i)-9.5(s)-10.2(ti)-9.5(c)-11(a)0.2(l )]TJ 0 -1.1391 TD -0.0087 Tc 0.0267 Tw [(fr)-10.7(a)-11.4(m)-1.3(e)-11.4(w)9.7(o)-11.3(r)-10.7(k t)-21.1(o)-11.2( )11.1(i)-9.9(n)-11.3(c)-11.4(o)-0.1(r)-10.7(p)-11.3(o)11.1(r)-21.9(at)-9.9(e a wi)-9.9(d)-11.3(e)-11.4( va)-11.4(ri)-9.9(et)-21.1(y)22.3( )-11.2(of)-10.7( l)-9.9(i)-9.9(n)-11.3(gu)-11.3(is)-10.6(-)]TJ 0 -1.1503 TD 0.002 Tc 0.1947 Tw [(tic)10.5( k)10.6(now)20.4(ledg)10.6(e )11.2(and)10.6( )11.2(sta)10.5(tist)12(i)12(cal m)9.4(o)10.6(de)10.5(ls )22.3(i)-10.4(n)10.6( )11.1(a)10.5( un)10.6(if)11.1(i)-10.4(e)-0.7(d)21.8( )]TJ T* 0.0022 Tc 0.0828 Tw [(w)20.6(a)-22.8(y)33.2(.)-4.7( Thi)12.2(r)0.2(d)10.8(,)6.5( w)9.5(e)-0.5( ev)22(alua)10.7(te)10.7( th)10.8(e )11.1(s)-10.8(y)33.2(stem)9.6(s p)10.8(e)10.7(r)-11(f)11.3(orm)9.6(a)-0.5(n)10.8(c)-0.5(e)21.8( )]TJ 0 -1.1391 TD -0.0089 Tc 0.1721 Tw [(o)-11.5(n)-0.3( )11.2(a)-11.6(n)-0.3( an)-11.5(no)-11.5(t)-10.1(a)-0.4(t)-21.3(e)-0.4(d te)-11.6(s)-10.8(t)1.1( )11.2(s)-10.8(e)-0.4(t,)-15.8( sh)-11.5(owi)-10.1(n)-11.5(g v)10.9(e)-11.6(r)-22.1(y)22.1( p)-11.4(r)-10.9(o)-11.5(m)-1.5(i)-10.1(s)-10.8(i)-21.3(n)-11.4(g)22( )]TJ T* 0.0022 Tc 0.1275 Tw [(resu)10.8(lt)12.2(s)11.5(.)-4.7( W)8.1(e)21.8( )-11.2(a)10.7(l)1(so)10.8( co)10.8(mp)10.8(a)10.7(r)0.2(e)10.7( )11.2(our)11.3( s)-10.8(y)33.2(stem)9.6( )-11.2(w)20.6(ith)10.8( )11.2(sev)10.8(e)-0.5(ra)10.7(l)12.2( )]TJ 0 -1.1503 TD -0.0177 Tw [(sta)10.7(t)1(e-)11.3(of)11.3(-the-)11.3(a)-0.5(rt)12.2( s)-10.8(y)33.1(stem)9.6(s,)6.5( tak)10.8(i)1(ng)10.8( i)12.2(n)-0.4(t)-10.2(o)22( acc)10.7(ou)10.8(nt)12.2( the)10.7( f)11.3(a)-0.5(c)10.7(t)12.2( )]TJ T* 0.0024 Tc 0.2166 Tw [(that)12.4( )11.1(t)12.4(h)-0.2(e)10.9( d)11(e)-0.3(f)11.5(i)1.2(ni)12.4(t)-10(i)12.4(on)22.2( of)22.7( )11.1(Ch)11(in)11(ese)10.9( w)20.8(o)-0.2(rds)11.7( v)11(a)10.9(ri)12.4(es)11.7( f)11.5(r)0.4(om)21( )]TJ 0 -1.1391 TD 0.0029 Tc -0.0072 Tw [(s)-10.1(y)33.9(stem)10.3( t)-9.5(o)11.5( sy)33.8(stem)10.3(. G)10.2(i)1.7(v)11.5(e)0.2(n)11.5( t)-9.5(h)22.7(e co)11.5(mp)11.5(ar)12(i)-9.5(s)1(o)11.5(n)22.7( )-11.2(re)11.4(sul)12.9(t)1.7(s)12.2(,)-4( w)21.3(e)11.4( )]TJ 0 -1.1503 TD 0.0028 Tc 0.0041 Tw [(can)22.6( sa)-11.1(y)33.8( w)21.2(i)1.6(t)-9.6(h)11.4( )11.2(con)11.4(f)0.8(ide)11.3(n)11.4(ce)11.3( th)11.4(a)11.3(t)12.8( ou)11.4(r)11.9( s)-10.2(y)44.9(st)-9.6(em)10.2( )11.2(ach)11.4(iev)11.4(e)0.1(s)12.1( )11.2(at)12.8( )]TJ 0 -1.1391 TD -0.0088 Tc 0.105 Tw [(l)-10(e)-11.5(a)-11.5(s)0.5(t )11.2(t)-21.2(h)-11.4(e)10.8( pe)-11.5(r)-22(f)0.3(or)-22(manc)-11.5(e )11.2(o)-11.4(f)0.3( s)-10.7(t)1.2(a)-11.5(t)-10(e)-11.5(-)0.3(o)-11.3(f-t)-21.2(h)-11.4(e)-0.3(-)-10.8(a)-11.5(r)-10.8(t)1.2( w)9.6(o)-11.4(r)-10.8(d)-0.2( )11.2(s)-10.7(e)-11.5(g-)]TJ T* 0.0026 Tc -0.0069 Tw [(m)10(e)-0.1(ntat)12.6(ion)11.2( s)-10.4(y)33.6(st)-9.8(em)10(s. )]TJ /F3 1 Tf 11.6798 0 0 11.6798 305.0409 481.7188 Tm -0.0125 Tc 0 Tw [(R)-9.7(e)-10.3(f)-18.5(e)-10.3(re)-20.6(n)-11.3(c)-20.6(es)-13.9( )]TJ /F5 1 Tf 8.76 0 0 8.76 305.0409 465.3988 Tm 0.0051 Tc -0.0085 Tw [(C)14.6(h)-1.7(e)10.7(n)-15.4(g)11.9(,)22.2( Ko)11.9(w)-12.6(k)11.9(-)9.3(S)-0.5(hi)9.1(ng)25.6(,)-5.2( )13.7(Gi)9.1(l)-4.6(b)-15.4(e)24.4(r)9.3(t)-4.6( H.)8.5( )-13.7(Y)14.8(o)12(n)-15.4(g)25.6( )-13.7(a)10.7(nd )13.7(Kam)16(-)9.3(Fa)10.7(i)-4.6( Wo)12(n)-15.4(g)11.9(.)8.5( )]TJ 1.0411 -1.1507 TD -0.0055 Tc 0.0021 Tw [(1)-12.3(9)-12.4(99)-12.3(.)11.6( A )-13.7(stu)-12.3(d)-12.4(y on)-12.3( w)-9.5(o)1.3(rd)-12.4(-)-15(b)-12.4(as)-13.8(e)13.8(d)-12.3( an)-12.4(d)-12.3( )13.7(i)-15.2(n)-12.3(tegr)-15(al-b)-12.3(i)-15.2(t)-1.5( C)-9.7(h)-12.3(in)-12.4(e)13.8(s)-13.8(e t)-15.2(e)13.8(x)-12.4(t)-15.2( )]TJ 0 -1.137 TD -0.0115 Tw [(co)-12.4(m)19(p)-12.5(r)-28.8(e)13.7(ssi)-29(on)-12.5( al)-29(gorit)-15.3(h)-26.1(m)19(s)-27.6(.)11.5( )]TJ /F6 1 Tf 10.0822 0 TD -0.007 Tc 0 Tw [(JAS)-13.8(I)-16.5(S)]TJ /F5 1 Tf 2.3973 0 TD 0.0072 Tc -0.0106 Tw [(,)24.3( 50\()11.4(3)0.4(\))11.4(:)-2.5( )13.7(21)14(8-2)14.1(28.)24.3( )]TJ -13.5206 -1.3836 TD 0.008 Tc -0.0525 Tw [(C)17.5(h)1.2(ie)27.3(n,)11.4( )13.7(L)-11.1(e)13.6(e)13.6(-)12.2(F)-11.3(e)27.3(n)-12.5(g)14.9(.)11.4( )13.7(1997.)11.4( P)16.1(A)4(T-)12.2(tr)12.2(e)13.6(e)27.3(-bas)13.4(e)27.3(d)1.1( )-13.7(k)14.8(e)-0.1(y)14.9(w)17.7(o)14.9(r)-1.5(d e)27.3(x)1.2(tr)12.2(a)13.6(c)13.6(tio)14.8(n f)12.2(o)14.8(r )]TJ 1.0411 -1.137 TD 0.009 Tc -0.0124 Tw [(C)18.5(h)2.2(ine)28.3(s)0.7(e)28.3( i)13(n)2.1(fo)15.8(rm)19.9(a)14.6(t)-0.7(i)13(o)15.9(n re)28.3(tr)13.2(iev)15.9(a)14.6(l. I)26.9(n)2.2( )]TJ /F6 1 Tf 13.3562 0 TD 0.0054 Tc 0 Tw [(SI)9.6(GI)9.6(R9)12.3(7)]TJ /F5 1 Tf 3.5068 0 TD 0.0069 Tc -0.0103 Tw [(,)24( 27-)11.1(31.)10.3( )]TJ -17.9041 -1.3836 TD 0.0066 Tc -0.01 Tw [(D)16.3(a)12.2(i,)23.7( )-13.7(Y)16.3(u)-0.2(bin,)23.7( Chr)10.8(i)10.6(st)10.6(o)13.4(phe)25.9(r)10.8( S.)10( G.)10( )13.7(Kh)-13.9(o)13.4(o)13.4( )-13.7(a)12.2(nd )13.7(Te)12.2(c)12.2(h)-0.3( Ee)12.2( )13.7(Lo)13.5(h)-13.9(.)23.7( 1999.)23.7( A)16.3( )]TJ 1.0411 -1.1507 TD -0.0051 Tc 0.0017 Tw [(n)-11.9(e)14.2(w)-9.1( st)-14.8(ati)-14.8(s)0.3(ti)-14.8(cal)-14.8( for)-14.6(m)5.8(u)-11.9(l)-1.1(a)-13.2( f)-14.6(o)1.8(r)-14.6( )13.7(C)-9.3(h)-12(in)-12(es)-27.1(e )13.7(w)-22.8(o)1.8(rd)-11.9( s)-13.4(e)0.5(gm)-7.9(e)14.2(n)-12(t)-14.8(a)0.5(ti)-14.8(on)-25.6( )13.7(i)-14.8(n)-11.9(-)]TJ 0 -1.137 TD -0.0053 Tc 0.0019 Tw [(corp)-12.2(ora)-13.4(tin)-25.8(g con)-12.2(t)-15(ex)-12.2(tu)-12.1(al)-15( )13.7(i)-15(n)-12.2(for)-14.8(m)5.6(ati)-15(o)-12.1(n)-12.1(.)11.8( )]TJ /F6 1 Tf 14.4795 0 TD 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