The life of Chinese-American teenager Tom Lee changes forever when he discovers he is part of a long lineage of magical protectors known as the Guardians. With guidance from a mythical tiger named Hu, Tom trains up to take on Loo, a force that is as powerful as a Guardian but with evil intentions to use magic to destroy humanity. To have a fighting chance against Loo, Tom must reunite all twelve Zodiac animal warriors and master his own newly discovered powers.