Microsoft Immunomics

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle

JCI Insight | April 2022, Vol 7(10)

DOI Preprint Publication Project Project

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon

JCI Insight | April 2022, Vol 7(10)

DOI Publication Project

Immunosequencing of the T-cell receptor repertoire reveals signatures specific for diagnosis and characterization of early Lyme disease

Julia Greissl, Mitch Pesesky, Sudeb C. Dalai, Alison W. Rebman, Mark J. Soloski, Elizabeth J. Horn, Jennifer N. Dines, Rachel M. Gittelman, Thomas M. Snyder, Ryan O. Emerson, Ted Meeds, Thomas Manley, Ian M. Kaplan, Lance Baldo, Jonathan M. Carlson, Harlan S. Robins, John N. Aucott

medRxiv | August 2021

DOI PDF Publication

Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection

Sudeb C. Dalai, Jennifer N. Dines, Thomas M. Snyder, Rachel M. Gittelman, Tera Eerkes, Pashmi Vaney, Sally Howard, Kipp Akers, Lynell Skewis, Anthony Monteforte, Pam Witte, Cristina Wolf, Hans Nesse, Megan Herndon, Jia Qadeer, Sarah Duffy, Emily Svejnoha, Caroline Taromino, Ian M. Kaplan, John Alsobrook, Thomas Manley, Lance Baldo

medRxiv | January 2021

DOI Publication

Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo’, Italy Through T-Cell Receptor Sequencing

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H Jabran Zahid, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Fabio Simeoni, Jessica Bordini, Nicola I LorÃ, Dejan Lazarevic, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Giovanni Tonon, Andrea Crisanti

medRxiv | November 2020

Updated February 11, 2021

DOI Publication

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins

August 2020

DOI Publication Publication Publication Publication Project

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

Thomas M Snyder, Rachel M Gittelman, Mark Klinger, Damon H May, Edward J Osborne, Ruth Taniguchi, H Jabran Zahid, Ian M Kaplan, Jennifer N Dines, Matthew N Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W Pesesky, Patricia De Almeida, Hope O'Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D'Angio, Paolo Bonfanti, Miranda F Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Helen C Su, Luigi D Notarangelo, Joaquin Martinez-Lopez, Jonathan M. Carlson, Harlan S Robins

medRxiv | August 2020

Updated September 17, 2020

DOI Publication Publication Publication Publication

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle

JCI Insight | April 2022, Vol 7(10)

DOI Preprint Publication Project Project

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon

JCI Insight | April 2022, Vol 7(10)

DOI Publication Project

Immunosequencing of the T-cell receptor repertoire reveals signatures specific for diagnosis and characterization of early Lyme disease

Julia Greissl, Mitch Pesesky, Sudeb C. Dalai, Alison W. Rebman, Mark J. Soloski, Elizabeth J. Horn, Jennifer N. Dines, Rachel M. Gittelman, Thomas M. Snyder, Ryan O. Emerson, Ted Meeds, Thomas Manley, Ian M. Kaplan, Lance Baldo, Jonathan M. Carlson, Harlan S. Robins, John N. Aucott

medRxiv | August 2021

DOI PDF Publication

Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection

Sudeb C. Dalai, Jennifer N. Dines, Thomas M. Snyder, Rachel M. Gittelman, Tera Eerkes, Pashmi Vaney, Sally Howard, Kipp Akers, Lynell Skewis, Anthony Monteforte, Pam Witte, Cristina Wolf, Hans Nesse, Megan Herndon, Jia Qadeer, Sarah Duffy, Emily Svejnoha, Caroline Taromino, Ian M. Kaplan, John Alsobrook, Thomas Manley, Lance Baldo

medRxiv | January 2021

DOI Publication

Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo’, Italy Through T-Cell Receptor Sequencing

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H Jabran Zahid, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Fabio Simeoni, Jessica Bordini, Nicola I LorÃ, Dejan Lazarevic, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Giovanni Tonon, Andrea Crisanti

medRxiv | November 2020

Updated February 11, 2021

DOI Publication

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins

August 2020

DOI Publication Publication Publication Publication Project

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

Thomas M Snyder, Rachel M Gittelman, Mark Klinger, Damon H May, Edward J Osborne, Ruth Taniguchi, H Jabran Zahid, Ian M Kaplan, Jennifer N Dines, Matthew N Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W Pesesky, Patricia De Almeida, Hope O'Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D'Angio, Paolo Bonfanti, Miranda F Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Helen C Su, Luigi D Notarangelo, Joaquin Martinez-Lopez, Jonathan M. Carlson, Harlan S Robins

medRxiv | August 2020

Updated September 17, 2020

DOI Publication Publication Publication Publication

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle

JCI Insight | April 2022, Vol 7(10)

DOI Preprint Publication Project Project

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon

JCI Insight | April 2022, Vol 7(10)

DOI Publication Project

Immunosequencing of the T-cell receptor repertoire reveals signatures specific for diagnosis and characterization of early Lyme disease

Julia Greissl, Mitch Pesesky, Sudeb C. Dalai, Alison W. Rebman, Mark J. Soloski, Elizabeth J. Horn, Jennifer N. Dines, Rachel M. Gittelman, Thomas M. Snyder, Ryan O. Emerson, Ted Meeds, Thomas Manley, Ian M. Kaplan, Lance Baldo, Jonathan M. Carlson, Harlan S. Robins, John N. Aucott

medRxiv | August 2021

DOI PDF Publication

Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection

Sudeb C. Dalai, Jennifer N. Dines, Thomas M. Snyder, Rachel M. Gittelman, Tera Eerkes, Pashmi Vaney, Sally Howard, Kipp Akers, Lynell Skewis, Anthony Monteforte, Pam Witte, Cristina Wolf, Hans Nesse, Megan Herndon, Jia Qadeer, Sarah Duffy, Emily Svejnoha, Caroline Taromino, Ian M. Kaplan, John Alsobrook, Thomas Manley, Lance Baldo

medRxiv | January 2021

DOI Publication

Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo’, Italy Through T-Cell Receptor Sequencing

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H Jabran Zahid, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Fabio Simeoni, Jessica Bordini, Nicola I LorÃ, Dejan Lazarevic, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Giovanni Tonon, Andrea Crisanti

medRxiv | November 2020

Updated February 11, 2021

DOI Publication

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

Thomas M Snyder, Rachel M Gittelman, Mark Klinger, Damon H May, Edward J Osborne, Ruth Taniguchi, H Jabran Zahid, Ian M Kaplan, Jennifer N Dines, Matthew N Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W Pesesky, Patricia De Almeida, Hope O'Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D'Angio, Paolo Bonfanti, Miranda F Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Helen C Su, Luigi D Notarangelo, Joaquin Martinez-Lopez, Jonathan M. Carlson, Harlan S Robins

medRxiv | August 2020

Updated September 17, 2020

DOI Publication Publication Publication Publication

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins

August 2020

DOI Publication Publication Publication Publication Project